<?xml version="1.0" encoding="UTF-8"?>
<HtpItem id="A0A1B0GVW7_HUMAN" transmembrane="yes" evidence="3D">
  <Name>Chloride voltage-gated channel 2 </Name>
  <CrossRef>
    <PDBTM id="7xf5">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7xja">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="8gqu">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="6qvc">
      <Chain id="B"/>
      <Chain id="A"/>
    </PDBTM>
    <PDBTM id="6qvu">
      <Chain id="B"/>
      <Chain id="A"/>
    </PDBTM>
    <PDBTM id="6qvb">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="6qvd">
      <Chain id="B"/>
      <Chain id="A"/>
    </PDBTM>
    <PDBTM id="8ta5">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="8ta4">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="6coy">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="6qv6">
      <Chain id="B"/>
      <Chain id="A"/>
    </PDBTM>
    <PDBTM id="8ta2">
      <Chain id="B"/>
      <Chain id="A"/>
    </PDBTM>
    <PDBTM id="8ta3">
      <Chain id="B"/>
      <Chain id="A"/>
    </PDBTM>
    <PDBTM id="5tqq">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="5tr1">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7cq7">
      <Chain id="C"/>
      <Chain id="D"/>
    </PDBTM>
    <PDBTM id="7cq5">
      <Chain id="C"/>
      <Chain id="D"/>
    </PDBTM>
    <PDBTM id="7cq6">
      <Chain id="C"/>
      <Chain id="D"/>
    </PDBTM>
    <PDBTM id="7bxu">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7jm6">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="8hvt">
      <Chain id="A"/>
      <Chain id="C"/>
    </PDBTM>
    <PDBTM id="3org">
      <Chain id="A"/>
      <Chain id="B"/>
      <Chain id="C"/>
      <Chain id="D"/>
    </PDBTM>
    <TOPDB id="CLCN2_HUMAN">
      <Alignment>
        <CrossRefSeq>ESRNTEMLAAACAVGVGCCFAAPIGGVLFSIEVTSTFFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQELPAFAVIGIASGFGGALFVYLNRKIVQVMRKQKTINRFLMRKRLLFPALVTLLISTLTFPPGFGQFMAGQLSQKETLVTLFDNRTWVRQGLVEELEPPSTSQAWNPPRANVFLTLVIFILMKFW-MSALATTIPVPCGAFMPVFVIGAAFGRLVGESMAA</CrossRefSeq>
        <OrigSeq>ESRNTEMLAAACAVGVGCCFAAPIGGVLFSIEVTSTFFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQELPAFAVIGIASGFGGALFVYLNRKIVQVMRKQKTINRFLMRKRLLFPALVTLLISTLTFPPGFGQFMAGQLSQKETLVTLFDNRTWVRQGLVEELEPPSTSQAWNPPRANVFLTLVIFILMKEQHLGVWWVKAWLPGS-QMEFIRTAAPTGLCLGATLWS</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="CLCN1_HUMAN">
      <Alignment>
        <CrossRefSeq>DILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGELMPREAISTLFDNNTWVKHAG--DPESLGQSAVWIHPRVNVVIIIFLFFVMKFW-MSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIM</CrossRefSeq>
        <OrigSeq>EMLAAACAVGVGCCFAAPIGGVLFSIEVTSTFFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQELPAFAVIGIASGFGGALFVYLNRKIVQVMRKQKTINRFLMRKRLLFPALVTLLISTLTFPPGFGQFMAGQLSQKETLVTLFDNRTWVRQGLVEELEPPSTSQAWNPPRANVFLTLVIFILMKEQHLGVWWVKAWLP-GSQMEFIRTAAPTGLCLGATL</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="CICH_TORMA">
      <Alignment>
        <CrossRefSeq>RADILTVGCALGISCCFGTPLAGVLFSIEVTCSHFGVRSYWRGFLGGAFSAFIFRVLSVWVKDTVTLTALFKTNFRGDIPFDLQEMPAFAIIGIASGFFGALFVYLNRQIIVFMRKKNFVTKILKKQRLIYPAVVTFVLATLRFPPGVGQFFGAGLMPRETINSLFDNYTWTK---TIDPRGLGNSAQWFIPHLNIFIVMALYFVMHFW-MAALAVTMPVPCGAFVPVFNLGAVLGRFVGELM</CrossRefSeq>
        <OrigSeq>NTEMLAAACAVGVGCCFAAPIGGVLFSIEVTSTFFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQELPAFAVIGIASGFGGALFVYLNRKIVQVMRKQKTINRFLMRKRLLFPALVTLLISTLTFPPGFGQFMAGQLSQKETLVTLFDNRTWVRQGLVEELEPPSTSQAWNPPRANVFLTLVIFILMKEQHLGVWWVKAWLPGS-QMEFIRTAAPTGLCLGATL</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="CLCKA_HUMAN">
      <Alignment>
        <CrossRefSeq>KSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWML-ILATTIPMPAGYFMPIFILGAAIGRLLGEAL</CrossRefSeq>
        <OrigSeq>ESRNTEMLAAACAVGVGCCFAAPIGGVLFSIEVTSTFFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQELPAFAVIGIASGFGGALFVYLNRKIVQVMRKQKTINRFLMRKRLLFPALVTLLISTLTFPPGFGQFMAGQLSQKETLVTLFDNRTWV------RQGLVEELEPPSTSQAWNPPRANVFLTLVIFILMKEQHLGVWWVKAWLPGS-QMEFIRTAAPTGLCLGATL</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="CLCN5_HUMAN">
      <Alignment>
        <CrossRefSeq>EAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSI---NPFGNSRLVLFYVEFHT--PWHLFELVPFILLGIFGGLWGALFIRTN---IAWCRKRKTTQ--LGKYPVIEVLVVTAITAILAFPNEY-----TRMSTSELISELFNDCGLLDSSKLCDYENRFNTSKGGELPDRPAGVGVYSAMWQLALTLILK-IVITIFTFGMKIPSGLFIPSMAVGAIAGRLLGVGM</CrossRefSeq>
        <OrigSeq>ESRNTEMLAAACAVGVGCCFAAPIGGVLFSIEVTSTFFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQELPAFAVIGIASGFGGALFVYLNRKIVQVMRKQKTINRFLMRKRLLFPALVTLLISTLTFPPGFGQFMAGQLSQKETLVTLFDNRTWVRQGLVEELEPP-STSQAWNPPR-------ANVFLTLVIFILMKEQHLGVWWVKAWLPGS-QMEFIRTAAPTGLCLGATL</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="GEF1_YEAST">
      <Alignment>
        <CrossRefSeq>SSQYEYITAASGAGVAVAFGAPIGGVLFGLEEIASANRFNSSTLWKSYYVALVAITTLKYI---DPFRNGRVILFNVTYDRD--WKVQEIPIFIALGIFGGLYGKYISKWNINFIHFRKMY------LSSWPVQEVLFLATLTALISYFNEFL-----KLDMTESMGILFHECVKNDNTSTFSHRLCQLDENTHAFEFL-----KIFTSLCFATVIRAL-LVVVSYGARVPAGIFVPSMAVGATFGRAVSLLV</CrossRefSeq>
        <OrigSeq>SRNTEMLAAACAVGVGCCFAAPIGGVLFSIEVTST--FFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQELPAFAVIGIASGFGGALFVYLNRKIVQVMRKQKTINRFLMRKRLLFPALVTLLISTLTFPPGFGQFMAGQLSQKETLVTLF------DNRTWVRQGLVEELEPPSTSQAWNPPRANVFLTLVIFILMKEQHLGVWWVKAWLPGS-QMEFIRTAAPTGLCLGATL</OrigSeq>
      </Alignment>
    </TOPDB>
  </CrossRef>
  <Sequence Length="256" CheckSum="f6ee73bcca20d54b06a794e3cecc6293">
    <Seq>
      XESRNTEMLA AACAVGVGCC FAAPIGGVLF SIEVTSTFFA VRNYWRGFFA
      ATFSAFIFRV LAVWNRDEET ITALFKTRFR LDFPFDLQEL PAFAVIGIAS
      GFGGALFVYL NRKIVQVMRK QKTINRFLMR KRLLFPALVT LLISTLTFPP
      GFGQFMAGQL SQKETLVTLF DNRTWVRQGL VEELEPPSTS QAWNPPRANV
      FLTLVIFILM KEQHLGVWWV KAWLPGSQME FIRTAAPTGL CLGATLWSGQ
      LRWQER
    </Seq>
  </Sequence>
  <Topology numTm="5" reliability="83.19">
    <Region from="1" to="12" loc="I"/>
    <Region from="13" to="31" loc="L"/>
    <Region from="32" to="43" loc="I"/>
    <Region from="44" to="63" loc="M"/>
    <Region from="64" to="89" loc="O"/>
    <Region from="90" to="110" loc="M"/>
    <Region from="111" to="132" loc="I"/>
    <Region from="133" to="147" loc="M"/>
    <Region from="148" to="203" loc="O"/>
    <Region from="204" to="221" loc="M"/>
    <Region from="222" to="223" loc="I"/>
    <Region from="224" to="238" loc="M"/>
    <Region from="239" to="256" loc="O"/>
  </Topology>
  <Predictions>
    <Prediction name="Hmmtop">
      <Region from="1" to="7" loc="O"/>
      <Region from="8" to="32" loc="M"/>
      <Region from="33" to="46" loc="I"/>
      <Region from="47" to="63" loc="M"/>
      <Region from="64" to="91" loc="O"/>
      <Region from="92" to="110" loc="M"/>
      <Region from="111" to="132" loc="I"/>
      <Region from="133" to="146" loc="M"/>
      <Region from="147" to="216" loc="O"/>
      <Region from="217" to="243" loc="M"/>
      <Region from="244" to="256" loc="I"/>
    </Prediction>
    <Prediction name="Memsat">
      <Region from="1" to="44" loc="I"/>
      <Region from="45" to="62" loc="M"/>
      <Region from="63" to="89" loc="O"/>
      <Region from="90" to="111" loc="M"/>
      <Region from="112" to="132" loc="I"/>
      <Region from="133" to="152" loc="M"/>
      <Region from="153" to="198" loc="O"/>
      <Region from="199" to="223" loc="M"/>
      <Region from="224" to="226" loc="I"/>
      <Region from="227" to="246" loc="M"/>
      <Region from="247" to="256" loc="O"/>
    </Prediction>
    <Prediction name="Octopus">
      <Region from="1" to="6" loc="I"/>
      <Region from="7" to="37" loc="M"/>
      <Region from="38" to="46" loc="O"/>
      <Region from="47" to="67" loc="M"/>
      <Region from="68" to="86" loc="I"/>
      <Region from="87" to="101" loc="M"/>
      <Region from="102" to="102" loc="O"/>
      <Region from="103" to="117" loc="M"/>
      <Region from="118" to="129" loc="I"/>
      <Region from="130" to="150" loc="M"/>
      <Region from="151" to="194" loc="O"/>
      <Region from="195" to="209" loc="M"/>
      <Region from="210" to="210" loc="I"/>
      <Region from="211" to="225" loc="M"/>
      <Region from="226" to="227" loc="O"/>
      <Region from="228" to="248" loc="M"/>
      <Region from="249" to="256" loc="I"/>
    </Prediction>
    <Prediction name="Philius">
      <Region from="1" to="7" loc="O"/>
      <Region from="8" to="32" loc="M"/>
      <Region from="33" to="43" loc="I"/>
      <Region from="44" to="63" loc="M"/>
      <Region from="64" to="89" loc="O"/>
      <Region from="90" to="111" loc="M"/>
      <Region from="112" to="131" loc="I"/>
      <Region from="132" to="152" loc="M"/>
      <Region from="153" to="199" loc="O"/>
      <Region from="200" to="218" loc="M"/>
      <Region from="219" to="230" loc="I"/>
      <Region from="231" to="251" loc="M"/>
      <Region from="252" to="256" loc="O"/>
    </Prediction>
    <Prediction name="Phobius">
      <Region from="1" to="5" loc="O"/>
      <Region from="6" to="32" loc="M"/>
      <Region from="33" to="43" loc="I"/>
      <Region from="44" to="64" loc="M"/>
      <Region from="65" to="89" loc="O"/>
      <Region from="90" to="112" loc="M"/>
      <Region from="113" to="132" loc="I"/>
      <Region from="133" to="152" loc="M"/>
      <Region from="153" to="199" loc="O"/>
      <Region from="200" to="220" loc="M"/>
      <Region from="221" to="256" loc="I"/>
    </Prediction>
    <Prediction name="Pro">
      <Region from="1" to="11" loc="O"/>
      <Region from="12" to="32" loc="M"/>
      <Region from="33" to="43" loc="I"/>
      <Region from="44" to="64" loc="M"/>
      <Region from="65" to="90" loc="O"/>
      <Region from="91" to="111" loc="M"/>
      <Region from="112" to="131" loc="I"/>
      <Region from="132" to="152" loc="M"/>
      <Region from="153" to="197" loc="O"/>
      <Region from="198" to="218" loc="M"/>
      <Region from="219" to="227" loc="I"/>
      <Region from="228" to="248" loc="M"/>
      <Region from="249" to="256" loc="O"/>
    </Prediction>
    <Prediction name="Prodiv">
      <Region from="1" to="10" loc="O"/>
      <Region from="11" to="31" loc="M"/>
      <Region from="32" to="42" loc="I"/>
      <Region from="43" to="63" loc="M"/>
      <Region from="64" to="90" loc="O"/>
      <Region from="91" to="111" loc="M"/>
      <Region from="112" to="132" loc="I"/>
      <Region from="133" to="153" loc="M"/>
      <Region from="154" to="193" loc="O"/>
      <Region from="194" to="214" loc="M"/>
      <Region from="215" to="223" loc="I"/>
      <Region from="224" to="244" loc="M"/>
      <Region from="245" to="256" loc="O"/>
    </Prediction>
    <Prediction name="Scampi2">
      <Region from="1" to="8" loc="O"/>
      <Region from="9" to="28" loc="M"/>
      <Region from="29" to="43" loc="I"/>
      <Region from="44" to="63" loc="M"/>
      <Region from="64" to="89" loc="O"/>
      <Region from="90" to="109" loc="M"/>
      <Region from="110" to="131" loc="I"/>
      <Region from="132" to="151" loc="M"/>
      <Region from="152" to="199" loc="O"/>
      <Region from="200" to="219" loc="M"/>
      <Region from="220" to="230" loc="I"/>
      <Region from="231" to="250" loc="M"/>
      <Region from="251" to="256" loc="O"/>
    </Prediction>
    <Prediction name="ScampiMsa2">
      <Region from="1" to="43" loc="I"/>
      <Region from="44" to="64" loc="M"/>
      <Region from="65" to="87" loc="O"/>
      <Region from="88" to="108" loc="M"/>
      <Region from="109" to="132" loc="I"/>
      <Region from="133" to="153" loc="M"/>
      <Region from="154" to="199" loc="O"/>
      <Region from="200" to="220" loc="M"/>
      <Region from="221" to="230" loc="I"/>
      <Region from="231" to="251" loc="M"/>
      <Region from="252" to="256" loc="O"/>
    </Prediction>
    <Prediction name="SignalP">
      <Region/>
    </Prediction>
    <Prediction name="TMHMM">
      <Region from="1" to="9" loc="O"/>
      <Region from="10" to="32" loc="M"/>
      <Region from="33" to="43" loc="I"/>
      <Region from="44" to="63" loc="M"/>
      <Region from="64" to="89" loc="O"/>
      <Region from="90" to="112" loc="M"/>
      <Region from="113" to="132" loc="I"/>
      <Region from="133" to="155" loc="M"/>
      <Region from="156" to="256" loc="O"/>
    </Prediction>
  </Predictions>
  <Constraints>
    <Constraint source="TOPDB" sourceId="5tqq_A">
      <ConstraintRegion from="48" to="50" loc="I" subId="17329333" subSource="5tqq_A"/>
      <ConstraintRegion from="51" to="78" loc="H" subId="17329335" subSource="5tqq_A"/>
      <ConstraintRegion from="79" to="93" loc="O" subId="17329337" subSource="5tqq_A"/>
      <ConstraintRegion from="94" to="112" loc="H" subId="17329338" subSource="5tqq_A"/>
      <ConstraintRegion from="113" to="144" loc="I" subId="17329339" subSource="5tqq_A"/>
      <ConstraintRegion from="145" to="159" loc="H" subId="17329341" subSource="5tqq_A"/>
      <ConstraintRegion from="160" to="160" loc="O" subId="17329344" subSource="5tqq_A"/>
      <ConstraintRegion from="161" to="174" loc="H" subId="17329346" subSource="5tqq_A"/>
      <ConstraintRegion from="175" to="203" loc="I" subId="17329348" subSource="5tqq_A"/>
      <ConstraintRegion from="204" to="227" loc="L" subId="17329350" subSource="5tqq_A"/>
      <ConstraintRegion from="228" to="236" loc="I" subId="17329351" subSource="5tqq_A"/>
      <ConstraintRegion from="237" to="257" loc="H" subId="17329354" subSource="5tqq_A"/>
      <ConstraintRegion from="276" to="276" loc="O" subId="17329356" subSource="5tqq_A"/>
      <ConstraintRegion from="277" to="307" loc="H" subId="17329358" subSource="5tqq_A"/>
      <ConstraintRegion from="308" to="313" loc="I" subId="17329360" subSource="5tqq_A"/>
      <ConstraintRegion from="314" to="322" loc="F" subId="17329361" subSource="5tqq_A"/>
      <ConstraintRegion from="323" to="323" loc="I" subId="17329362" subSource="5tqq_A"/>
      <ConstraintRegion from="324" to="341" loc="H" subId="17329364" subSource="5tqq_A"/>
      <ConstraintRegion from="342" to="347" loc="O" subId="17329366" subSource="5tqq_A"/>
      <ConstraintRegion from="348" to="359" loc="L" subId="17329368" subSource="5tqq_A"/>
      <ConstraintRegion from="360" to="400" loc="O" subId="17329370" subSource="5tqq_A"/>
      <ConstraintRegion from="401" to="420" loc="H" subId="17329373" subSource="5tqq_A"/>
      <ConstraintRegion from="421" to="421" loc="I" subId="17329376" subSource="5tqq_A"/>
      <ConstraintRegion from="422" to="441" loc="H" subId="17329378" subSource="5tqq_A"/>
      <ConstraintRegion from="442" to="453" loc="O" subId="17329380" subSource="5tqq_A"/>
      <ConstraintRegion from="457" to="464" loc="O" subId="17329383" subSource="5tqq_A"/>
      <ConstraintRegion from="465" to="480" loc="H" subId="17329386" subSource="5tqq_A"/>
      <ConstraintRegion from="481" to="481" loc="I" subId="17329389" subSource="5tqq_A"/>
      <ConstraintRegion from="482" to="495" loc="H" subId="17329391" subSource="5tqq_A"/>
      <ConstraintRegion from="496" to="496" loc="O" subId="17329393" subSource="5tqq_A"/>
      <ConstraintRegion from="497" to="516" loc="H" subId="17329396" subSource="5tqq_A"/>
      <ConstraintRegion from="517" to="605" loc="I" subId="17329399" subSource="5tqq_A"/>
      <ConstraintRegion from="618" to="683" loc="I" subId="17329402" subSource="5tqq_A"/>
      <ConstraintRegion from="48" to="50" loc="I" subId="17329407" subSource="5tqq_B"/>
      <ConstraintRegion from="51" to="78" loc="H" subId="17329410" subSource="5tqq_B"/>
      <ConstraintRegion from="79" to="93" loc="O" subId="17329413" subSource="5tqq_B"/>
      <ConstraintRegion from="94" to="112" loc="H" subId="17329416" subSource="5tqq_B"/>
      <ConstraintRegion from="113" to="144" loc="I" subId="17329419" subSource="5tqq_B"/>
      <ConstraintRegion from="145" to="159" loc="H" subId="17329421" subSource="5tqq_B"/>
      <ConstraintRegion from="160" to="160" loc="O" subId="17329423" subSource="5tqq_B"/>
      <ConstraintRegion from="161" to="174" loc="H" subId="17329424" subSource="5tqq_B"/>
      <ConstraintRegion from="175" to="203" loc="I" subId="17329425" subSource="5tqq_B"/>
      <ConstraintRegion from="204" to="227" loc="L" subId="17329427" subSource="5tqq_B"/>
      <ConstraintRegion from="228" to="236" loc="I" subId="17329428" subSource="5tqq_B"/>
      <ConstraintRegion from="237" to="257" loc="H" subId="17329430" subSource="5tqq_B"/>
      <ConstraintRegion from="276" to="276" loc="O" subId="17329432" subSource="5tqq_B"/>
      <ConstraintRegion from="277" to="307" loc="H" subId="17329433" subSource="5tqq_B"/>
      <ConstraintRegion from="308" to="313" loc="I" subId="17329435" subSource="5tqq_B"/>
      <ConstraintRegion from="314" to="322" loc="F" subId="17329437" subSource="5tqq_B"/>
      <ConstraintRegion from="323" to="323" loc="I" subId="17329438" subSource="5tqq_B"/>
      <ConstraintRegion from="324" to="341" loc="H" subId="17329439" subSource="5tqq_B"/>
      <ConstraintRegion from="342" to="347" loc="O" subId="17329440" subSource="5tqq_B"/>
      <ConstraintRegion from="348" to="359" loc="L" subId="17329442" subSource="5tqq_B"/>
      <ConstraintRegion from="360" to="400" loc="O" subId="17329445" subSource="5tqq_B"/>
      <ConstraintRegion from="401" to="420" loc="H" subId="17329447" subSource="5tqq_B"/>
      <ConstraintRegion from="421" to="421" loc="I" subId="17329449" subSource="5tqq_B"/>
      <ConstraintRegion from="422" to="441" loc="H" subId="17329452" subSource="5tqq_B"/>
      <ConstraintRegion from="442" to="453" loc="O" subId="17329455" subSource="5tqq_B"/>
      <ConstraintRegion from="457" to="464" loc="O" subId="17329458" subSource="5tqq_B"/>
      <ConstraintRegion from="465" to="480" loc="H" subId="17329461" subSource="5tqq_B"/>
      <ConstraintRegion from="481" to="481" loc="I" subId="17329463" subSource="5tqq_B"/>
      <ConstraintRegion from="482" to="495" loc="H" subId="17329465" subSource="5tqq_B"/>
      <ConstraintRegion from="496" to="496" loc="O" subId="17329467" subSource="5tqq_B"/>
      <ConstraintRegion from="497" to="516" loc="H" subId="17329470" subSource="5tqq_B"/>
      <ConstraintRegion from="517" to="605" loc="I" subId="17329472" subSource="5tqq_B"/>
      <ConstraintRegion from="618" to="683" loc="I" subId="17329474" subSource="5tqq_B"/>
    </Constraint>
    <Constraint source="TOPDB" sourceId="5tr1_A">
      <ConstraintRegion from="36" to="36" loc="I" subId="17328838" subSource="5tr1_A"/>
      <ConstraintRegion from="37" to="46" loc="F" subId="17328839" subSource="5tr1_A"/>
      <ConstraintRegion from="47" to="71" loc="H" subId="17328840" subSource="5tr1_A"/>
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  </Constraints>
</HtpItem>
