FIG4 phosphoinositide 5-phosphatase EVVKIASLMGFIKLKLNRYAIIANTVEETGRFNGHVFYRVLQHSIVSTKFNSRI--DSEEAEYIKLLELHLKNSTFYF---------------------------------SYTYDLTNSLQRNEKVGPAASWKTADERFFWNHYLTEDLRNFAHQDPRIDSFIQPVIYGYAKTVDAVLNATPIVLGLITRRSIFRAGTRYFRRGVDKDGNVGNFNETEQILLAENPESEKIHVF-SFLQTRGSVPIYWA-EINNLKYKPNLVLG--ENSLDATKKHFDQQKELYGDNYL-VNLVNQKG---HELPVKEGYESVVHALN-----DPKIHYVYFDFHHECRKMQWHRVKLLIDHLEKLGLSNEDFFHKVIDS--------------NGNTVEIVNEQHSVVRTNCMDCLDRTNVVQSVLAQWVLQKEFESADVVATGSTWEDNAPLLTSYQNLWADNADAVSVAYSGTGALKTDFTRTGKRTRLGAFNDFLNSASRYYQNNWTDGPRQDSYDLFLGGFRP----------------HTASIKSPFPDRRPVYIQLIPMIICAALTVLGATIFFPKDRFTSSKNLLYFAGASIVLALSTKFMFKNGIQFVNWPKLVDV RAVSAFGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKVEDTNMIYIPNDSVRVTHPDEARYLRIFQNVDLSSNFYFSYDLSHSLQYNLTVLRMPLEMLKSEMTQNRQESFDIFEDEGLITQGGS-GVFGICSEPYMKYVWNGELLDIIKSTVHRD-----WLLYIIHGFCGQSKLLIYGRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSYVQVRGSVPLYWSQDISTMMPKPPITLDQADPFAHVAALHFDQMFQRFGSPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHTIVYIPWDMAKYTKSKLCNVLDRLNVIAESV-VKKTGFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQTGILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDT-DAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHPTEGKPHLWELPTDFYLHHKNTMRLLPTRRSYTYWWTPEVIKHLPLPYD----------------------EVICAVNLKKLIVK--KFHKYEEEIDI MPTAAAPIIS SVQKLVLYET RARYFLVGSN NAETKYRVLK IDRTEPKDLV IIDDRHVYTQ QEVRELLGRL DLGNRTKMGQ KGSSGLFRAV SAFGVVGFVR FLEGYYIVLI TKRRKMADIG GHAIYKVEDT NMIYIPNDSV RVTHPDEARY LRIFQNVDLS SNFYFSYDLS HSLQYNLTVL RMPLEMLKSE MTQNRQESFD IFEDEGLITQ GGSGVFGICS EPYMKYVWNG ELLDIIKSTV HRDWLLYIIH GFCGQSKLLI YGRPVYVTLI ARRSSKFAGT RFLKRGANCE GDVANEVETE QILCDASVMS FTAGSYSSYV QVRGSVPLYW SQDISTMMPK PPITLDQADP FAHVAALHFD QMFQRFGSPI IILNLVKERE KRKHERILSE ELVAAVTYLN QFLPPEHTIV YIPWDMAKYT KSKLCNVLDR LNVIAESVVK KTGFFVNRPD SYCSILRPDE KWNELGGCVI PTGRLQTGIL RTNCVDCLDR TNTAQFMVGK CALAYQLYSL GLIDKPNLQF DTDAVRLFEE LYEDHGDTLS LQYGGSQLVH RVKTYRKIAP WTQHSKDIMQ TLSRYYSNAF SDADRQDSIN LFLGVFHPTE GKPHLWELPT DFYLHHKNTM RLLPTRRSYT YWWTPEVIKH LPLPYDEVIC AVNLKKLIVK KFHKYEEEID IHNEFFRPYE LSSFDDTFCL AMTSSARDFM PKTVGIDPSP FTVRKPDETG KSVLGNKSNR EEAVLQRKTA ASAPPPPSEE AVSSSSEDDS GTDREEEGSV SQRSTPVKMT DAGDSAKVTE NVVQPMKELY GINLSDGLSE EDFSIYSRFV QLGQSQHKQD KNSQQPCSRC SDGVIKLTPI SAFSQDNIYE VQPPRVDRKS TEIFQAHIQA SQGIMQPLGK EDSSMYREYI RNRYL