{"@attributes":{"id":"A0A8I5KYJ3_HUMAN","transmembrane":"yes","evidence":"Experiment"},"Name":"Endoplasmic reticulum metallopeptidase 1 ","CrossRef":{"TOPDB":[{"@attributes":{"id":"ERMP1_HUMAN"},"Alignment":{"CrossRefSeq":"MEWGSESAAVRRHRVGVERREGAAAAPPPEREARAQEPLVDGCSGGGRTRKRSPGGSGGASRGAGTGLSEVRAALGLALYLIALRTLVQLSLQQLVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEVQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLIRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLKHLATSDMLAAASKYRHGNMVFFDVLGLFVIAYPSRIGSIINYMVVMGVVLYLGKKFLQPKHKTGNYKKDFLCGLGITLISWFTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTATVAKIILIHTLAKRFYYMNASAQYLGEVFFDISLFVHCCFLVTLTYQGLCSAFISAVWVAFPLLTKLCVHKDFKQHGAQGKFIAFYLLGMFIPYLYALYLIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTMILSSYFINFIYLAKSTKKTMLTLTLVCAITFLLVCSGTFFPYSSNPANPKPKRVFLQHMTRTFHDLEGNAVKRDSGIWINGFDYTGISHITPHIPEINDSIRAHCEENAPLCGFPWYLPVHFLIRKNWYLPAPEVSPRNPPHFRLISKEQTPWDSIKLTFEATGPSHMSFYVRAHKGSTLSQWSLGNGTPVTSKGGDYFVFYSHGLQASAWQFWIEVQVSEEHPEGMVTVAIAAHYLSGEDKRSPQLDALKEKFPDWTFPSAW","OrigSeq":"MEWGSESAAVRRHRVGVERREGAAAAPPPEREARAQEPLVDGCSGGGRTRKRSPGGSGGASRGAGTGLSEVRAALGLALYLIALRTLVQLSLQQLVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEVQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLIRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLKHLATSDMLAAASKYRHGNMVFFDVLGLFVIAYPSRIGSIINYMVVMGVVLYLGKKFLQPKHKTGNYKKDFLCGLGITLISWFTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTATVAKIILIHTLAKRFYYMNASAQYLGEVFFDISLFVHCCFLVTLTYQGLCSAFISAVWVAFPLLTKLCVHKDFKQHGAQGKFIAFYLLGMFIPYLYALYLIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTMILSSYFINFIYLAKSTKKTMLTLTLVCAITFLLVCSGTFFPYSSNPANPKPKRVFLQHMTRTFHDLEGNAVKRDSGIWINGFDYTGISHITPHIPEINDSIRAHCEENAPLCGFPWYLPVHFLIRKNWYLPAPEVSPRNPPHFRLISKEQTPWDSIKLTFEATGPSHMSFYVRAHKGSTLSQWSLGNGTPVTSKGGDYFVFYSHGLQASAWQFWIEVQVSEEHPEGMVTVAIAAHYLSGEDKRSPQLDALKEKFPDWTFPSAW"}},{"@attributes":{"id":"ERP1B_CAEEL"},"Alignment":{"CrossRefSeq":"LRPAHWNFIGLFFLVLIIGTTFLHKCLPEPKDPNQEETQFSEKRAVKVLQELSDYGWKPAGSYNCEELTRNRILKELNDIRSQNQNVENLRFDIDTQYVSGCFDIPAHDTEGMNICYRNVSNVMARLGKGEKKDKISVLLNCHYDSWPTSNAGSDDLSSCALMLELIRLYSKNPHLLNHDVIFLFNGAEESSLLAAHGFITQHSWRHEIRAFINLEASGSGGRELLFQAGPANQWLLNSYLEAAIHPHCSVIGQEVFQSGVYPGDTDFRIFRDHGRVPGLDLAFVQNGYWWHTEFDTAERITKGSLQRAGENVYSTLNHLLKSPYLEKPAEYADRKTVFFDFLGLFVIIYPLSIAHLVNMLTICTVIALMSHRF---------YSKTFITFLALRDYVLTILTIALVLKAMTFMSLFTYGALRWYTRHWLALVAYGLPSVWAGISVQGLLTARLAPKAREEYG-STLELIHLTLISGILLAFTYYDIASGF------LFALLLVPAIKSIITYFGAWPTCPTFNTILTLILSFPGCAMAIYTTEMLLSIFIPIMGRSSYNPEPAVSFFVAFSAGCIVLSLGGLVAKSRNSRSSNEAGL-LELIYNILGVLLVTLTILYVFSSFWPSPYRFDNVYPTAKRTQFFHVNQMLYDRNGQISVNDTRFYAISHDYRGAEDI-PFVKKDPEYTGLQCHYENNPWCETPFLFPTKGRLNERNIRVRSVDERLKFKHPVKILGISKRHGVDSKDGKGNIEYSFSVIGTGQISVYIIPD-----TTWLITNTSVTQPKTPQENMFLYYTCSTPNNICEWMFKVTIKKTTQTPSDDKPLLIGISSHYLHGPEMQSESIKNMIAKIQENRVNSPEWTVTASAWN","OrigSeq":"LSEVRAALGLALYLIALRTLVQLSLQQLVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEVQSNSLH--KISVDVQRPTGSFSID--FLGGFTSYYDNITNVVVKL-EPRDGAQHAVLANCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLIRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLKHLATSDMLAAASKYRHGNMVFFDVLGLFVIAYPSRIGSIINYMVVMGVVLYLGKKFLQPKHKTGNYKKDFLCGLGITLISWFTSLVTVLIIA-VFISLIGQS-LSWYNHFYVSVCLYGTATVAKIILIHTLAKRFYYMNASAQYLGEVFFDISLFVHCCFLVTLTYQGLCSAFISAVWVAFPLLTKLCVHKDFKQHGAQGKFIAF----YLLGMFIPYLYALYLIWAVFEMFTPILGRSGSEIPPDV-VLASILAGCTMILSSYFINFIYLAKSTKKTMLTLTLVCAITFLLVCSGTFF---------PYSSNPANPKPKRVFLQHMTRTFHDLEGNAVKRDSGIWINGFDYTGISHITPHIPEINDSIRAHCE-ENAPLCGFPWYLPVH-FLIRKNWYLPAPE--VSPRNPPHFRLISKE-----QTPWDSIKLTFEATGPSHMSFYVRAHKGSTLSQWSLGNGTPVTSKG--GDYFVFYSHGL--QASAWQFWIEVQVSEEHP--EGMVTVAIAAHYLSGEDKRSPQLDALKEKF-------PDWTF-PSAWG"}},{"@attributes":{"id":"ERP1A_CAEEL"},"Alignment":{"CrossRefSeq":"KNQPEDDQRTKRGRESIGFRHW--IYFVLTVAIVYAGVVALHRKMPAVRDGTS-FEDFSEQRARVLLKQLTALGSRPSGSDNLEVKAFGMIQDRIGKIHSVVDEVGVNRLESDVQRPSGCFDLKFLSSFTLCYHKITNVVVRIGPKKGPSGNSLLLNCHFDTMPDTPGATDDAVACTIMMDVLEVLAHSKTELENDVVFLFNGAEENFLQAAHGFINQHPWRHDIRAFINLEGTGSGGREILFQAGPGNSWLLQTYLENAPHPFCSVLAQEIFQSGIIPSDTDFRIFRDYGRISGLDIAYTKNGWFYHTEFDEEWRIEPGAIQRAGENVLAVVRAILKSPYLEKPATFDEENRWVFYDVVGLFTVYYSVNVGKLLNYIACFATYFLVVLRIRNRLYSVG----DLAIAFKHHVVAFLAMVITMLLIIAFVVQMDLVMCWYKMPEIVGALY----VLPMLIAGAIVHSHYADNNRIRNVEMVQYDTILLSFASILFLMTFYNLSSAFYVLNNLILPVFKDIII-WALGLFGVIRRVTPRVLFFTQLFCFLPTFVFAAYAISQCVDFFVPVMGRLGNAINPEFIMGPL----GLVIASGFILFVNNLFYISRRMNYIIRLLFAIFALFILVLITTKVGNPYEYSHENPRLRRIIALHANRTIYDFEGHLTQKDNALFVHSLDYRGASDLPDH-SFLQGSSAPNCTGVVDEYCRMPYYTAIHELFPPEQSLWVPVPSPVVLPYPIDLKLVSRHAMG-ENLNLTFEIRGGYDKMSLHVTPLNDYDLLSWSFTDIDIKEFGRRQTYFVFMTYGHEAPEVRRFWILLKNKNGVAPDPEKHEN--IELSVATHYAHGIYQDTETLRQLRAMI","OrigSeq":"KRSPGGSGGASRG-AGTGLSEVRAALGLALYLIALRTLVQLSLQQLVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLI--EVQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGAQH-AVLANCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLIRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLKHLATSDMLAAASKYRHGNM-VFFDVLGLFVIAYPSRIGSIINYMVVMGVVLYLGKKFLQPKHKTGNYKKDFLCGLGITLISWFTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTATVAKIILIHTLAKRFYYMNASAQYLGEVFFDISLFVHCCFLVTLTYQGLCSAFISAVWVAFPLLTKLCVHKDFKQHGAQ----GKFIAFYLLGMFIPYL-YALYLIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTMILSSYFINF----IYLAKSTKKTMLTLTLVCAITFL-LVCSGTFFPYSSNPANPKPKRVFLQHMTRTFHDLEGNAVKRDSGIWINGFDYTGISHITPHIPEINDSIRAHCEENA-PLCGFPWYLPVHFLI---RKNWYLPAPEVSPRNPPHFRLISKEQTPWDSIKLTFEATGP-SHMSFYVRAHKGSTLSQWSLGN-GTPVTSKGGDYFVFYSHGLQASA-WQFWIEVQVS-------EEHPEGMVTVAIAAHYLSGEDKRSPQLDALKEKF"}},{"@attributes":{"id":"GCP2_CAEEL"},"Alignment":{"CrossRefSeq":"ILKRLSGRPAPSDWQGFVGGNLTYKLGPGFVNGEKLSINVHSELRTKRIRNVIGYIRGSEEPDSYIMLGNHFDAWV--YGSIDPNSGTAVLAEVARAMMQTINETSWKPARTIVFNAWDAEEFGLIGSTEFVEEFVNILQKRAVVYINMDCI-QGNISLHVDTVPILEHAVIEASKQVENPSKRERSRGRKTLYDTWMKVFPDKKAGVPKIRVPGGGSDHAPFLNFAGVPVINFTFKNYTTWDTYPLYHTMYET","OrigSeq":"LLEQIKLIEVQSNSLHKISVD--VQRPTGSFSIDFLGGFTSYY---DNITNVVVKLEPRDGAQHAVLANCHFDSVANSPGASDDAVSCSVMLEVLRVLSTS----SEALHHAVIFLFNGAEENVLQASHGFITQ--HPWASLIRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHP------------FASVV------AQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAF-----IENGYIYHTKYDT"}},{"@attributes":{"id":"TFR2_HUMAN"},"Alignment":{"CrossRefSeq":"ASRLLRKLKGPVAPQEWQGSLLGSPYHLGPGPRLRLVVNNHRTSTPINNIFGCIEGRSEPDHYVVIGAQRDAW--GPGAAKSAVGTAILLELVRTFSSMVSNGFRPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAVVYVSLDNAVLGDDKFHAKTSPLLTSLIESVLKQVDSPNHSGQTLYEQVVFTNPSWDAEVIRPLPMDSSAYSFTAFVGVPAVEFSFMEDDQAYPFLHTKEDTYENLHK","OrigSeq":"VHYLLEQIKLIEVQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPGASDDAVSCSVMLEVLRVLST---SSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLIRA--FINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPF--ASVVAQEVFQ---------SGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIY---HTKYDTADRILT"}},{"@attributes":{"id":"NCLN_HUMAN"},"Alignment":{"CrossRefSeq":"IASVEGRLTGLGGEDLPTIVIVAHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFAS-GGGKFNYQGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAF","OrigSeq":"ITNVVVKLEP-RDGAQHAVLANCHFDSVANSP----GASDDAVSCSVMLEVLRVLS-----TSSEALHHAVIFLFNGAEENVLQASHGFITQH-------PWASLIRAFINLEAAGVGGKELVFQTGPENPWLVQAYV"}}]},"Sequence":{"@attributes":{"Length":"896","CheckSum":"63e764d26f4cf3d40857e49b4731ade6"},"Seq":"\n      MEWGSESAAV RRHRVGVERR EGAAAAPPPE REARAQEPLV DGCSGGGRTR\n      KRSPGGSGGA SRGAGTGLSE VRAALGLALY LIALRTLVQL SLQQLVLRGA\n      AGHRGEFDAL QARDYLEHIT SIGPRTTGSP ENEILTVHYL LEQIKLIEVQ\n      SNSLHKISVD VQRPTGSFSI DFLGGFTSYY DNITNVVVKL EPRDGAQHAV\n      LANCHFDSVA NSPGASDDAV SCSVMLEVLR VLSTSSEALH HAVIFLFNGA\n      EENVLQASHG FITQHPWASL IRAFINLEAA GVGGKELVFQ TGPENPWLVQ\n      AYVSAAKHPF ASVVAQEVFQ SGIIPSDTDF RIYRDFGNIP GIDLAFIENG\n      YIYHTKYDTA DRILTDSIQR AGDNILAVLK HLATSDMLAA ASKYRHGNMV\n      FFDVLGLFVI AYPSRIGSII NYMVVMGVVL YLGKKFLQPK HKTGNYKKDF\n      LCGLGITLIS WFTSLVTVLI IAVFISLIGQ SLSWYNHFYV SVCLYGTATV\n      AKIILIHTLA KRFYYMNASA QYLGEVFFDI SLFVHCCFLV TLTYQGLCSA\n      FISAVWVAFP LLTKLCVHKD FKQHGAQGKF IAFYLLGMFI PYLYALYLIW\n      AVFEMFTPIL GRSGSEIPPD VVLASILAGC TMILSSYFIN FIYLAKSTKK\n      TMLTLTLVCA ITFLLVCSGT FFPYSSNPAN PKPKRVFLQH MTRTFHDLEG\n      NAVKRDSGIW INGFDYTGIS HITPHIPEIN DSIRAHCEEN APLCGFPWYL\n      PVHFLIRKNW YLPAPEVSPR NPPHFRLISK EQTPWDSIKL TFEATGPSHM\n      SFYVRAHKGS TLSQWSLGNG TPVTSKGGDY FVFYSHGLQA SAWQFWIEVQ\n      VSEEHPEGMV TVAIAAHYLS GEDKRSPQLD ALKEKFPDWT FPSAWG\n    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