HECT-type E3 ubiquitin transferase MKVDRTKLKK TPTEAPADCR ALIDKLKVCN DEQLLLELQQ IKTWNIGKCE LYHWVDLLDR FDGILADAGQ TVENMSWMLV CDRPEREQLK MLLLAVLNFT ALLIEYSFSR HLYSSIEHLT TLLASSDMQV VLAVLNLLYV FSKRSNYITR LGSDKRTPLL TRLQHLAESW GGKENGFGLA ECCRDLHMMK YPPSATTLHF EFYADPGAEV KIEKRTTSNT LHYIHIEQLD KISESPSEIM ESLTKMYSIP KDKQMLLFTH IRLAHGFSNH RKRLQAVQAR LHAISILVYS NALQESANSI LYNGLIEELV DVLQITDKQL MEIKAASLRT LTSIVHLERT PKLSSIIDCT GTASYHGFLP VLVRNCIQAM IDPSMDPYPH QFATALFSFL YHLASYDAGG EALVSCGMME ALLKVIKFLG DEQDQITFVT RAVRVVDLIT NLDMAAFQSH SGLSIFIYRL EHEVDLCRKE CPFVIKPKIQ RPNTTQEGEE METDMDGVQC IPQRAALLKS MLNFLKKAIQ DPAFSDGIRH VMDGSLPTSL KHIISNAEYY GPSLFLLATE VVTVFVFQEP SLLSSLQDNG LTDVMLHALL IKDVPATREV LGSLPNVFSA LCLNARGLQS FVQCQPFERL FKVLLSPDYL PAMRRRRSSD PLGDTASNLG SAVDELMRHQ PTLKTDATTA IIKLLEEICN LGRDPKYICQ KPSIQKADGT ATAPPPRSNH AAEEASSEDE EEEEVQAMQS FNSTQQNETE PNQQVVGTEE RIPIPLMDYI LNVMKFVESI LSNNTTDDHC QEFVNQKGLL PLVTILGLPN LPIDFPTSAA CQAVAGVCKS ILTLSHEPKV LQEGLLQLDS ILSSLEPLHR PIESPGGSVL LRELACAGNV ADATLSAQAT PLLHALTAAH AYIMMFVHTC RVGQSEIRSI SVNQWGSQLG LSVLSKLSQL YCSLVWESTV LLSLCTPNSL PSGCEFGQAD MQKLVPKDEK AGTTQGGKRS DGEQDGAAGS MDASTQGLLE GIGLDGDTLA PMETDEPTAS DSKGKSKITP AMAARIKQIK PLLSASSRLG RALAELFGLL VKLCVGSPVR QRRSHHAAST TTAPTPAARS TASALTKLLT KGLSWQPPPY TPTPRFRLTF FICSVGFTSP MLFDERKYPY HLMLQKFLCS GGHNALFETF NWALSMGGKV PVSEGLEHSD LPDGTGEFLD AWLMLVEKMV NPTTVLESPH SLPAKLPGGV QNFPQFSALR FLVVTQKAAF TCIKNLWNRK PLKVYGGRMA ESMLAILCHI LRGEPVIRER LSKEKEGSRG EEDTGQEEGG SRREPQVNQQ QLQQLMDMGF TREHAMEALL NTSTMEQATE YLLTHPPPIM GGVVRDLSMS EEDQMMRAIA MSLGQDIPMD QRAESPEEVA CRKEEEERKA REKQEEEEAK CLEKFQDADP LEQDELHTFT DTMLPGCFHL LDELPDTVYR VCDLIMTAIK RNGADYRDMI LKQVVNQVWE AADVLIKAAL PLTTSDTKTV SEWISQMATL PQASNLATRI LLLTLLFEEL KLPCAWVVES SGILNVLIKL LEVVQPCLQA AKEQKEVQTP KWITPVLLLI DFYEKTAISS KRRAQMTKYL QSNSNNWRWF DDRSGRWCSY SASNNSTIDS AWKSGETSVR FTAGRRRYTV QFTTMVQVNE ETGNRRPVML TLLRVPRLNK NSKNSNGQEL EKTLEESKEM DIKRKENKGN DTPLALESTN TEKETSLEET KIGEILIQGL TEDMVTVLIR ACVSMLGVPV DPDTLHATLR LCLRLTRDHK YAMMFAELKS TRMILNLTQS SGFNGFTPLV TLLLRHIIED PCTLRHTMEK VVRSAATSGA GSTTSGVVSG SLGSREINYI LRVLGPAACR NPDIFTEVAN CCIRIALPAP RGSGTASDDE FENLRIKGPN AVQLVKTTPL KPSPLPVIPD TIKEVIYDML NALAAYHAPE EDKSDPKPGV MTQEVGQLLQ DMGDDVYQQY RSLTRQSSDF DTQSGFSINS QVFAADGAST ETSASGTSQG EASTPEESRD GKKDKEGDRA SEEGKQKGKG SKPLMPTSTI LRLLAELVRS YVGIATLIAN YSYTVGQSEL IKEDCSVLAF VLDHLLPHTQ NAEDKDTPAL ARLFLASLAA AGSGTDAQVA LVNEVKAALG RALAMAESTE KHARLQAVMC IISTIMESCP STSSFYSSAT AKTQHNGMNN IIRLFLKKGL VNDLARVPHS LDLSSPNMAN TVNAALKPLE TLSRIVNQPS SLFGSKSASS KNKSEQDAQG ASQDSSSNQQ DPGEPGEAEV QEEDHDVTQT EVADGDIMDG EAETDSVVIA GQPEVLSSQE MQVENELEDL IDELLERDGG SGNSTIIVSR SGEDESQEDV LMDEAPSNLS QASTLQANRE DSMNILDPED EEEHTQEEDS SGSNEDEDDS QDEEEEEEED EEDDQEDDEG EEGDEDDDDD GSEMELDEDY PDMNASPLVR FERFDREDDL IIEFDNMFSS ATDIPPSPGN IPTTHPLMVR HADHSSLTLG SGSSTTRLTQ GIGRSQRTLR QLTANTGHTI HVHYPGNRQP NPPLILQRLL GPSAAADILQ LSSSLPLQSR GRARLLVGND DVHIIARSDD ELLDDFFHDQ STATSQAGTL SSIPTALTRW TEECKVLDAE SMHDCVSVVK VSIVNHLEFL RDEELEERRE KRRKQLAEEE TKITDKGKED KENRDQSAQC TASKSNDSTE QNLSDGTPMP DSYPTTPSST DAATSESKET LGTLQSSQQQ PTLPTPPALG EVPQELQSPA GEGGSSTQLL MPVEPEELGP TRPSGEAETT QMELSPAPTI TSLSPERAED SDALTAVSSQ LEGSPMDTSS LASCTLEEAV GDTSAAGSSE QPRAGSSTPG DAPPAVAEVQ GRSDGSGESA QPPEDSSPPA SSESSSTRDS AVAISGADSR GILEEPLPST SSEEEDPLAG ISLPEGVDPS FLAALPDDIR REVLQNQLGI RPPTRTAPST NSSAPAVVGN PGVTEVSPEF LAALPPAIQE EVLAQQRAEQ QRRELAQNAS SDTPMDPVTF IQTLPSDLRR SVLEDMEDSV LAVMPPDIAA EAQALRREQE ARQRQLMHER LFGHSSTSAL SAILRSPAFT SRLSGNRGVQ YTRLAVQRGG TFQMGGSSSH NRPSGSNVDT LLRLRGRLLL DHEALSCLLV LLFVDEPKLN TSRLHRVLRN LCYHAQTRHW VIRSLLSILQ RSSESELCIE TPKLTTSEEK GKKSSKSCGS SSHENRPLDL LHKMESKSSN QLSWLSVSMD AALGCRTNIF QIQRSGGRKH TEKHASGGST VHIHPQAAPV VCRHVLDTLI QLAKVFPSHF TQQRTKETNC ESDRERGNKA CSPCSSQSSS SGICTDFWDL LVKLDNMNVS RKGKNSVKSV PVSAGGEGET SPYSLEASPL GQLMNMLSHP VIRRSSLLTE KLLRLLSLIS IALPENKVSE AQANSGSGAS STTTATSTTS TTTTTAASTT PTPPTAPTPV TSAPALVAAT AISTIVVAAS TTVTTPTTAT TTVSISPTTK GSKSPAKVSD GGSSSTDFKM VSSGLTENQL QLSVEVLTSH SCSEEGLEDA ANVLLQLSRG DSGTRDTVLK LLLNGARHLG YTLCKQIGTL LAELREYNLE QQRRAQCETL SPDGLPEEQP QTTKLKGKMQ SRFDMAENVV IVASQKRPLG GRELQLPSMS MLTSKTSTQK FFLRVLQVII QLRDDTRRAN KKAKQTGRLG SSGLGSASSI QAAVRQLEAE ADAIIQMSES SQSEASVRRE ESPMDVDQPS PSAQDTQSIA SDGTPQGEKE KEERPPELPL LSEQLSLDEL WDMLGECLKE LEESHDQHAV LVLQPAVEAF FLVHATERES KPPVRDTQTH RTVLNQILRQ STTHLADGPF AVLVDYIRVL DFDVKRKYFR QELERLDEGL RKEDMAVHVR RDHVFEDSYR ELHRKSPEEM KNRLYIVFEG EEGQDAGGLL REWYMIISRE MFNPMYALFR TSPGDRVTYT INPSSHCNPN HLSYFKFVGR IVAKAVYDNR LLECYFTRSF YKHILGKSVR YTDMESEDYH FYQGLVYLLE NDVSTLGYDL TFSTEVQEFG VCEVRDLKPN GANILVTEEN KKEYVHLVCQ MRMTGAIRKQ LAAFLEGFYE IIPKRLISIF TEQELELLIS GLPTIDIDDL KSNTEYHKYQ SNSIQIQWFW RALRSFDQAD RAKFLQFVTG TSKVPLQGFA ALEGMNGIQK FQIHRDDRST DRLPSAHTCF NQLDLPAYES FEKLRHMLLL AIQECSEGFG LA