{"@attributes":{"id":"A0A9L9PXW9_HUMAN","transmembrane":"yes","evidence":"Exists"},"Name":"Phosphatidylinositol-3-phosphatase SAC1 ","CrossRef":{"PDBTM":[{"@attributes":{"id":"8c81"},"Chain":{"@attributes":{"id":"E"}}},{"@attributes":{"id":"3lwt"},"Chain":{"@attributes":{"id":"X"}}},{"@attributes":{"id":"4tu3"},"Chain":{"@attributes":{"id":"X"}}}],"TOPDB":{"@attributes":{"id":"SAC1_YEAST"},"Alignment":{"CrossRefSeq":"FFKLAEGKGTNDAVIHLANQDQGVRVLGAEEFPVQGEVVKIASLMGFIKLKLNRYAIIANTVEETGRFNGHVFYRVLQHSIVSTKFNSRIDSEEAEYIKLLELHLKNSTFYFSYTYDLTNSLQRNEKVGPAASWKTADERFFWNHYLTEDLRNFAHQDPRIDSFIQPVIYGYAKTVDAVLNATPIVLGLITRRSIFRAGTRYFRRGVDKDGNVGNFNETEQILLAENPESEKIHVFSFLQTRGSVPIYWAEINNLKYKPNLVL--GENSLDATKKHFDQQKELYGDNYLVNLVNQKGHELPVKEGYESVVHALNDPKIHYVYFDFHHECRKMQWHRVKLLIDHLEKLGLSNEDFFHKVIDSNGNTVEIVNEQHSVVRTNCMDCLDRTNVVQSVLAQWVLQKEFESADVVATGSTWEDNAPLLTSYQNLWADNADAVSVAYSGTGALKTDFTRTGKRTRLGAFNDFLNSASRYYQNNWTDGPRQDSYDLFLGGFRPHTASIKSPFPDRRPVYIQLIPMIICAALTVLGATIFFPKDRFTSSKNLLYFAGASIVLALSTKFMFKNGIQFVNWPKLV","OrigSeq":"FYVEACDDGADD-VLTIDRVSTEVTLAVKKDVPPSAVTRPIFGILGTIHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVL--------------SYKKTMLHLT----------DIQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSA----QPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSKA------SFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEM---QDELSYFLVDSAG---QVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVASIGTFF--IILYNGKDFVDAPRLV"}}},"Sequence":{"@attributes":{"Length":"554","CheckSum":"ed0b935c9951893e5afb64fc34d70bd1"},"Seq":"\n      MATAAYEQLK LHITPEKFYV EACDDGADDV LTIDRVSTEV TLAVKKDVPP\n      SAVTRPIFGI LGTIHLVAGN YLIVITKKIK VGEFFSHVVW KATDFDVLSY\n      KKTMLHLTDI QRLSNTSPEF QEMSLLERAD QRFVWNGHLL RELSAQPEVH\n      RFALPVLHGF ITMHSCSING KYFDWILISR RSCFRAGVRY YVRGIDSEGH\n      AANFVETEQI VHYNGSKASF VQTRGSIPVF WSQRPNLKYK PLPQISKVAN\n      HMDGFQRHFD SQVIIYGKQV IINLINQKGS EKPLEQTFAT MVSSLGSGMM\n      RYIAFDFHKE CKNMRWDRLS ILLDQVAEMQ DELSYFLVDS AGQVVANQEG\n      VFRSNCMDCL DRTNVIQSLL ARRSLQAQLQ RLGVLHVGQK LEEQDEFEKI\n      YKNAWADNAN ACAKQYAGTG ALKTDFTRTG KRTHLGLIMD GWNSMIRYYK\n      NNFSDGFRQD SIDLFLGNYS VDELESHSPL SVPRDWKFLA LPIIMVVAFS\n      MCIICLLMAG DTWTETLAYV LFWGVASIGT FFIILYNGKD FVDAPRLVQK\n      EKID\n    "},"Topology":{"@attributes":{"numTm":"2","reliability":"65.23"},"Region":[{"@attributes":{"from":"1","to":"487","loc":"I"}},{"@attributes":{"from":"488","to":"509","loc":"M"}},{"@attributes":{"from":"510","to":"515","loc":"O"}},{"@attributes":{"from":"516","to":"535","loc":"M"}},{"@attributes":{"from":"536","to":"554","loc":"I"}}]},"Predictions":{"Prediction":[{"@attributes":{"name":"Hmmtop"},"Region":[{"@attributes":{"from":"1","to":"55","loc":"I"}},{"@attributes":{"from":"56","to":"75","loc":"M"}},{"@attributes":{"from":"76","to":"488","loc":"O"}},{"@attributes":{"from":"489","to":"510","loc":"M"}},{"@attributes":{"from":"511","to":"515","loc":"I"}},{"@attributes":{"from":"516","to":"535","loc":"M"}},{"@attributes":{"from":"536","to":"554","loc":"O"}}]},{"@attributes":{"name":"Memsat"},"Region":[{"@attributes":{"from":"1","to":"56","loc":"O"}},{"@attributes":{"from":"57","to":"74","loc":"M"}},{"@attributes":{"from":"75","to":"151","loc":"I"}},{"@attributes":{"from":"152","to":"167","loc":"M"}},{"@attributes":{"from":"168","to":"490","loc":"O"}},{"@attributes":{"from":"491","to":"507","loc":"M"}},{"@attributes":{"from":"508","to":"516","loc":"I"}},{"@attributes":{"from":"517","to":"536","loc":"M"}},{"@attributes":{"from":"537","to":"554","loc":"O"}}]},{"@attributes":{"name":"Octopus"},"Region":[{"@attributes":{"from":"1","to":"51","loc":"I"}},{"@attributes":{"from":"52","to":"72","loc":"M"}},{"@attributes":{"from":"73","to":"150","loc":"O"}},{"@attributes":{"from":"151","to":"171","loc":"M"}},{"@attributes":{"from":"172","to":"486","loc":"I"}},{"@attributes":{"from":"487","to":"507","loc":"M"}},{"@attributes":{"from":"508","to":"514","loc":"O"}},{"@attributes":{"from":"515","to":"535","loc":"M"}},{"@attributes":{"from":"536","to":"554","loc":"I"}}]},{"@attributes":{"name":"Philius"},"Region":[{"@attributes":{"from":"1","to":"286","loc":"O"}},{"@attributes":{"from":"287","to":"305","loc":"M"}},{"@attributes":{"from":"306","to":"487","loc":"I"}},{"@attributes":{"from":"488","to":"510","loc":"M"}},{"@attributes":{"from":"511","to":"516","loc":"O"}},{"@attributes":{"from":"517","to":"538","loc":"M"}},{"@attributes":{"from":"539","to":"554","loc":"I"}}]},{"@attributes":{"name":"Phobius"},"Region":[{"@attributes":{"from":"1","to":"56","loc":"O"}},{"@attributes":{"from":"57","to":"75","loc":"M"}},{"@attributes":{"from":"76","to":"487","loc":"I"}},{"@attributes":{"from":"488","to":"510","loc":"M"}},{"@attributes":{"from":"511","to":"515","loc":"O"}},{"@attributes":{"from":"516","to":"536","loc":"M"}},{"@attributes":{"from":"537","to":"554","loc":"I"}}]},{"@attributes":{"name":"Pro"},"Region":[{"@attributes":{"from":"1","to":"490","loc":"I"}},{"@attributes":{"from":"491","to":"511","loc":"M"}},{"@attributes":{"from":"512","to":"515","loc":"O"}},{"@attributes":{"from":"516","to":"536","loc":"M"}},{"@attributes":{"from":"537","to":"554","loc":"I"}}]},{"@attributes":{"name":"Prodiv"},"Region":[{"@attributes":{"from":"1","to":"487","loc":"I"}},{"@attributes":{"from":"488","to":"508","loc":"M"}},{"@attributes":{"from":"509","to":"516","loc":"O"}},{"@attributes":{"from":"517","to":"537","loc":"M"}},{"@attributes":{"from":"538","to":"554","loc":"I"}}]},{"@attributes":{"name":"Scampi2"},"Region":[{"@attributes":{"from":"1","to":"487","loc":"I"}},{"@attributes":{"from":"488","to":"508","loc":"M"}},{"@attributes":{"from":"509","to":"515","loc":"O"}},{"@attributes":{"from":"516","to":"536","loc":"M"}},{"@attributes":{"from":"537","to":"554","loc":"I"}}]},{"@attributes":{"name":"ScampiMsa2"},"Region":[{"@attributes":{"from":"1","to":"487","loc":"I"}},{"@attributes":{"from":"488","to":"508","loc":"M"}},{"@attributes":{"from":"509","to":"515","loc":"O"}},{"@attributes":{"from":"516","to":"536","loc":"M"}},{"@attributes":{"from":"537","to":"554","loc":"I"}}]},{"@attributes":{"name":"SignalP"},"Region":{}},{"@attributes":{"name":"TMHMM"},"Region":[{"@attributes":{"from":"1","to":"487","loc":"O"}},{"@attributes":{"from":"488","to":"510","loc":"M"}},{"@attributes":{"from":"511","to":"516","loc":"I"}},{"@attributes":{"from":"517","to":"536","loc":"M"}},{"@attributes":{"from":"537","to":"554","loc":"O"}}]}]},"Constraints":{}}