IQ motif and Sec7 domain ArfGEF 2 MSPGPPRAPG PSSPVRALAS RRPPPPAGPG GGWRRERAGT GLSCPFPCPW AARMEAGSGP PGGPGSESPN RAVEYLLELN NIIESQQQLL ETQRRRIEEL EGQLDQLTQE NRDLREESQL HRGELHRDPH GARDSPGRES QYQNLRETQF HHRELRESQF HQAARDVGYP NREGAYQNRE AVYRDKERDA SYPLQDTTGY TARERDVAQC HLHHENPALG RERGGREAGP AHPGREKEAG YSAAVGVGPR PPRERGQLSR GASRSSSPGA GGGHSTSTST SPATTLQRKS DGENSRTVSV EGDAPGSDLS TAVDSPGSQP PYRLSQLPPS SSHMGGPPAG VGLPWAQRAR LQPASVALRK QEEEEIKRSK ALSDSYELST DLQDKKVEML ERKYGGSFLS RRAARTIQTA FRQYRMNKNF ERLRSSASES RMSRRIILSN MRMQFSFEEY EKAQNPAYFE GKPASLDEGA MAGARSHRLE RGLPYGGSCG GGIDGGGSSV TTSGEFSNDI TELEDSFSKQ VKSLAESIDE ALNCHPSGPM SEEPGSAQLE KRESKEQQED SSATSFSDLP LYLDDTVPQQ SPERLPSTEP PPQGRPEFWA PAPLPPVPPP VPSGTREDGS REEGTRRGPG CLECRDFRLR AAHLPLLTIE PPSDSSVDLS DRSDRGSVHR QLVYEADGCS PHGTLKHKGP PGRAPIPHRH YPAPEGPAPA PPGPLPPAPN SGTGPSGVAG GRRLGKCEAA GENSDGGDNE SLESSSNSNE TINCSSGSSS RDSLREPPAT GLCKQTYQRE TRHSWDSPAF NNDVVQRRHY RIGLNLFNKK PEKGIQYLIE RGFLSDTPVG VAHFILERKG LSRQMIGEFL GNRQKQFNRD VLDCVVDEMD FSSMDLDDAL RKFQSHIRVQ GEAQKVERLI EAFSQRYCVC NPALVRQFRN PDTIFILAFA IILLNTDMYS PSVKAERKMK LDDFIKNLRG VDNGEDIPRD LLVGIYQRIQ GRELRTNDDH VSQVQAVERM IVGKKPVLSL PHRRLVCCCQ LYEVPDPNRP QRLGLHQREV FLFNDLLVVT KIFQKKKILV TYSFRQSFPL VEMHMQLFQN SYYQFGIKLL SAVPGGERKV LIIFNAPSLQ DRLRFTSDLR ESIAEVQEME KYRVESELEK QKGMMRPNAS QPGGAKDSVN GTMARSSLED TYGAGDGLKR GALSSSLRDL SDAGKRGRRN SVGSLDSTIE GSVISSPRPH QRMPPPPPPP PPEEYKSQRP VSNSSSFLGS LFGSKRGKGP FQMPPPPTGQ ASASSSSASS THHHHHHHHH GHSHGGLGVL PDGQSKLQAL HAQYCQGPGP APPPYLPPQQ PSLPPPPQQP PPLPQLGSIP PPPASAPPVG PHRHFHAHGP VPGPQHYTLG RPGRAPRRGA GGHPQFAPHG RHPLHQPTSP LPLYSPAPQH PPAHKQGPKH FIFSHHPQMM PAAGAAGGPG SRPPGGSYSH PHHPQSPLSP HSPIPPHPSY PPLPPPSPHT PHSPLPPTSP HGPLHASGPP GTANPPSANP KAKPSRISTV V