<?xml version="1.0" encoding="UTF-8"?>
<HtpItem id="C9JK45_HUMAN" transmembrane="yes" evidence="3D">
  <Name>Solute carrier family 35 member E1 </Name>
  <CrossRef>
    <PDBTM id="5y78">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="5y79">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <TOPDB id="YMD8_YEAST">
      <Alignment>
        <CrossRefSeq>TETTVLSIVRGIVLLILPGFAVFLLTICEFSILEQTPVLTVSIVGIVKELLTVIFGIIILSERLSGFYNWLGMLIIMADVCYYNYFRYKQDLLQKYH--SVSTQDNRN</CrossRefSeq>
        <OrigSeq>AQTYVYQWPWTLLLLAVSGFCNFAQNVIAFSILNLVSPLSYSVANATKRIMVITVSLIMLRNPVT-STNVLGMMTAILGVFLYNKTKYDANQQARKHLLPVTTADLSS</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="YJT3_YEAST">
      <Alignment>
        <CrossRefSeq>SSTVIKAFPVSLFLL--NGTFHFIQAMITFHLLGEVSTLTYSIANLMKRFAIIAVSWVFIGRRITWLQVFGLVLNTLGLFLYERCTSQSKIKAK</CrossRefSeq>
        <OrigSeq>AQTYVYQWPWTLLLLAVSGFCNFAQNVIAFSILNLVSPLSYSVANATKRIMVITVSLIMLRNPVTSTNVLGMMTAILGVFLYNKTKYDANQQAR</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="SLY41_YEAST">
      <Alignment>
        <CrossRefSeq>TVALVAIHGIAHFFQAMLAFQLIGLLSSINYSVANIMKRIVVISVA-LFWETKLNFFQVFGVILTIAGLYGYDKWGLSKKDGRQA</CrossRefSeq>
        <OrigSeq>TLLLLAVSGFCNFAQNVIAFSILNLVSPLSYSVANATKRIMVITVSLIMLRNPVTSTNVLGMMTAILGVFLYNKTKYDANQQARK</OrigSeq>
      </Alignment>
    </TOPDB>
  </CrossRef>
  <Sequence Length="116" CheckSum="f23f41696c42c4528e97bc273973d7cf">
    <Seq>
      MAQTYVYQWP WTLLLLAVSG FCNFAQNVIA FSILNLVSPL SYSVANATKR
      IMVITVSLIM LRNPVTSTNV LGMMTAILGV FLYNKTKYDA NQQARKHLLP
      VTTADLSSKE RHRSPL
    </Seq>
  </Sequence>
  <Topology numTm="2" reliability="75.8">
    <Region from="1" to="10" loc="I"/>
    <Region from="11" to="34" loc="M"/>
    <Region from="35" to="64" loc="O"/>
    <Region from="65" to="82" loc="M"/>
    <Region from="83" to="116" loc="I"/>
  </Topology>
  <Predictions>
    <Prediction name="Hmmtop">
      <Region from="1" to="11" loc="I"/>
      <Region from="12" to="25" loc="M"/>
      <Region from="26" to="27" loc="O"/>
      <Region from="28" to="45" loc="M"/>
      <Region from="46" to="50" loc="I"/>
      <Region from="51" to="62" loc="M"/>
      <Region from="63" to="64" loc="O"/>
      <Region from="65" to="82" loc="M"/>
      <Region from="83" to="116" loc="I"/>
    </Prediction>
    <Prediction name="Memsat">
      <Region from="1" to="13" loc="O"/>
      <Region from="14" to="41" loc="M"/>
      <Region from="42" to="44" loc="I"/>
      <Region from="45" to="60" loc="M"/>
      <Region from="61" to="68" loc="O"/>
      <Region from="69" to="84" loc="M"/>
      <Region from="85" to="116" loc="I"/>
    </Prediction>
    <Prediction name="Octopus">
      <Region from="1" to="7" loc="O"/>
      <Region from="8" to="38" loc="M"/>
      <Region from="39" to="50" loc="I"/>
      <Region from="51" to="65" loc="M"/>
      <Region from="66" to="66" loc="O"/>
      <Region from="67" to="81" loc="M"/>
      <Region from="82" to="116" loc="I"/>
    </Prediction>
    <Prediction name="Philius">
      <Region from="1" to="10" loc="I"/>
      <Region from="11" to="34" loc="M"/>
      <Region from="35" to="64" loc="O"/>
      <Region from="65" to="84" loc="M"/>
      <Region from="85" to="116" loc="I"/>
    </Prediction>
    <Prediction name="Phobius">
      <Region from="1" to="10" loc="O"/>
      <Region from="11" to="22" loc="O"/>
      <Region from="23" to="30" loc="O"/>
      <Region from="31" to="64" loc="O"/>
      <Region from="65" to="83" loc="M"/>
      <Region from="84" to="116" loc="I"/>
    </Prediction>
    <Prediction name="Pro">
      <Region from="1" to="4" loc="O"/>
      <Region from="5" to="25" loc="M"/>
      <Region from="26" to="40" loc="I"/>
      <Region from="41" to="61" loc="M"/>
      <Region from="62" to="65" loc="O"/>
      <Region from="66" to="86" loc="M"/>
      <Region from="87" to="116" loc="I"/>
    </Prediction>
    <Prediction name="Prodiv">
      <Region from="1" to="11" loc="I"/>
      <Region from="12" to="32" loc="M"/>
      <Region from="33" to="62" loc="O"/>
      <Region from="63" to="83" loc="M"/>
      <Region from="84" to="116" loc="I"/>
    </Prediction>
    <Prediction name="Scampi2">
      <Region/>
    </Prediction>
    <Prediction name="ScampiMsa2">
      <Region/>
    </Prediction>
    <Prediction name="SignalP">
      <Region/>
    </Prediction>
    <Prediction name="TMHMM">
      <Region from="1" to="11" loc="I"/>
      <Region from="12" to="34" loc="M"/>
      <Region from="35" to="64" loc="O"/>
      <Region from="65" to="84" loc="M"/>
      <Region from="85" to="116" loc="I"/>
    </Prediction>
  </Predictions>
  <Constraints>
    <Constraint source="TOPDB" sourceId="5y78_A">
      <ConstraintRegion from="100" to="110" loc="I" subId="17432812" subSource="5y78_A"/>
      <ConstraintRegion from="111" to="127" loc="H" subId="17432815" subSource="5y78_A"/>
      <ConstraintRegion from="128" to="137" loc="O" subId="17432818" subSource="5y78_A"/>
      <ConstraintRegion from="138" to="161" loc="H" subId="17432821" subSource="5y78_A"/>
      <ConstraintRegion from="162" to="174" loc="I" subId="17432822" subSource="5y78_A"/>
      <ConstraintRegion from="175" to="192" loc="H" subId="17432824" subSource="5y78_A"/>
      <ConstraintRegion from="193" to="197" loc="O" subId="17432826" subSource="5y78_A"/>
      <ConstraintRegion from="198" to="214" loc="H" subId="17432828" subSource="5y78_A"/>
      <ConstraintRegion from="215" to="227" loc="I" subId="17432831" subSource="5y78_A"/>
      <ConstraintRegion from="228" to="243" loc="H" subId="17432833" subSource="5y78_A"/>
      <ConstraintRegion from="244" to="250" loc="O" subId="17432836" subSource="5y78_A"/>
      <ConstraintRegion from="251" to="267" loc="H" subId="17432839" subSource="5y78_A"/>
      <ConstraintRegion from="268" to="286" loc="I" subId="17432841" subSource="5y78_A"/>
      <ConstraintRegion from="287" to="307" loc="H" subId="17432843" subSource="5y78_A"/>
      <ConstraintRegion from="308" to="329" loc="O" subId="17432845" subSource="5y78_A"/>
      <ConstraintRegion from="330" to="347" loc="H" subId="17432847" subSource="5y78_A"/>
      <ConstraintRegion from="348" to="355" loc="I" subId="17432849" subSource="5y78_A"/>
      <ConstraintRegion from="356" to="371" loc="H" subId="17432852" subSource="5y78_A"/>
      <ConstraintRegion from="372" to="381" loc="O" subId="17432854" subSource="5y78_A"/>
      <ConstraintRegion from="382" to="397" loc="H" subId="17432858" subSource="5y78_A"/>
      <ConstraintRegion from="398" to="404" loc="I" subId="17432862" subSource="5y78_A"/>
      <ConstraintRegion from="100" to="110" loc="I" subId="17432871" subSource="5y78_B"/>
      <ConstraintRegion from="111" to="127" loc="H" subId="17432874" subSource="5y78_B"/>
      <ConstraintRegion from="128" to="137" loc="O" subId="17432877" subSource="5y78_B"/>
      <ConstraintRegion from="138" to="161" loc="H" subId="17432880" subSource="5y78_B"/>
      <ConstraintRegion from="162" to="174" loc="I" subId="17432883" subSource="5y78_B"/>
      <ConstraintRegion from="175" to="192" loc="H" subId="17432887" subSource="5y78_B"/>
      <ConstraintRegion from="193" to="197" loc="O" subId="17432891" subSource="5y78_B"/>
      <ConstraintRegion from="198" to="214" loc="H" subId="17432894" subSource="5y78_B"/>
      <ConstraintRegion from="215" to="227" loc="I" subId="17432899" subSource="5y78_B"/>
      <ConstraintRegion from="228" to="242" loc="H" subId="17432904" subSource="5y78_B"/>
      <ConstraintRegion from="243" to="250" loc="O" subId="17432907" subSource="5y78_B"/>
      <ConstraintRegion from="251" to="267" loc="H" subId="17432912" subSource="5y78_B"/>
      <ConstraintRegion from="268" to="286" loc="I" subId="17432915" subSource="5y78_B"/>
      <ConstraintRegion from="287" to="307" loc="H" subId="17432918" subSource="5y78_B"/>
      <ConstraintRegion from="308" to="329" loc="O" subId="17432922" subSource="5y78_B"/>
      <ConstraintRegion from="330" to="347" loc="H" subId="17432926" subSource="5y78_B"/>
      <ConstraintRegion from="348" to="353" loc="I" subId="17432929" subSource="5y78_B"/>
      <ConstraintRegion from="354" to="371" loc="H" subId="17432933" subSource="5y78_B"/>
      <ConstraintRegion from="372" to="381" loc="O" subId="17432936" subSource="5y78_B"/>
      <ConstraintRegion from="382" to="398" loc="H" subId="17432941" subSource="5y78_B"/>
      <ConstraintRegion from="399" to="404" loc="I" subId="17432945" subSource="5y78_B"/>
      <ConstraintRegion from="100" to="107" loc="I" subId="17433016" subSource="5y79_A"/>
      <ConstraintRegion from="108" to="127" loc="H" subId="17433018" subSource="5y79_A"/>
      <ConstraintRegion from="128" to="137" loc="O" subId="17433021" subSource="5y79_A"/>
      <ConstraintRegion from="138" to="161" loc="H" subId="17433024" subSource="5y79_A"/>
      <ConstraintRegion from="162" to="174" loc="I" subId="17433028" subSource="5y79_A"/>
      <ConstraintRegion from="175" to="192" loc="H" subId="17433032" subSource="5y79_A"/>
      <ConstraintRegion from="193" to="197" loc="O" subId="17433036" subSource="5y79_A"/>
      <ConstraintRegion from="198" to="214" loc="H" subId="17433040" subSource="5y79_A"/>
      <ConstraintRegion from="215" to="226" loc="I" subId="17433041" subSource="5y79_A"/>
      <ConstraintRegion from="227" to="243" loc="H" subId="17433042" subSource="5y79_A"/>
      <ConstraintRegion from="244" to="250" loc="O" subId="17433045" subSource="5y79_A"/>
      <ConstraintRegion from="251" to="270" loc="H" subId="17433047" subSource="5y79_A"/>
      <ConstraintRegion from="271" to="285" loc="I" subId="17433050" subSource="5y79_A"/>
      <ConstraintRegion from="286" to="306" loc="H" subId="17433053" subSource="5y79_A"/>
      <ConstraintRegion from="307" to="329" loc="O" subId="17433055" subSource="5y79_A"/>
      <ConstraintRegion from="330" to="347" loc="H" subId="17433058" subSource="5y79_A"/>
      <ConstraintRegion from="348" to="352" loc="I" subId="17433060" subSource="5y79_A"/>
      <ConstraintRegion from="353" to="371" loc="H" subId="17433063" subSource="5y79_A"/>
      <ConstraintRegion from="372" to="381" loc="O" subId="17433066" subSource="5y79_A"/>
      <ConstraintRegion from="382" to="399" loc="H" subId="17433068" subSource="5y79_A"/>
      <ConstraintRegion from="400" to="404" loc="I" subId="17433070" subSource="5y79_A"/>
      <ConstraintRegion from="100" to="108" loc="I" subId="17433076" subSource="5y79_B"/>
      <ConstraintRegion from="109" to="127" loc="H" subId="17433079" subSource="5y79_B"/>
      <ConstraintRegion from="128" to="137" loc="O" subId="17433082" subSource="5y79_B"/>
      <ConstraintRegion from="138" to="163" loc="H" subId="17433085" subSource="5y79_B"/>
      <ConstraintRegion from="164" to="174" loc="I" subId="17433088" subSource="5y79_B"/>
      <ConstraintRegion from="175" to="192" loc="H" subId="17433091" subSource="5y79_B"/>
      <ConstraintRegion from="193" to="197" loc="O" subId="17433093" subSource="5y79_B"/>
      <ConstraintRegion from="198" to="214" loc="H" subId="17433094" subSource="5y79_B"/>
      <ConstraintRegion from="215" to="226" loc="I" subId="17433095" subSource="5y79_B"/>
      <ConstraintRegion from="227" to="242" loc="H" subId="17433099" subSource="5y79_B"/>
      <ConstraintRegion from="243" to="250" loc="O" subId="17433102" subSource="5y79_B"/>
      <ConstraintRegion from="251" to="270" loc="H" subId="17433105" subSource="5y79_B"/>
      <ConstraintRegion from="271" to="285" loc="I" subId="17433109" subSource="5y79_B"/>
      <ConstraintRegion from="286" to="307" loc="H" subId="17433112" subSource="5y79_B"/>
      <ConstraintRegion from="308" to="329" loc="O" subId="17433116" subSource="5y79_B"/>
      <ConstraintRegion from="330" to="347" loc="H" subId="17433117" subSource="5y79_B"/>
      <ConstraintRegion from="348" to="352" loc="I" subId="17433120" subSource="5y79_B"/>
      <ConstraintRegion from="353" to="371" loc="H" subId="17433125" subSource="5y79_B"/>
      <ConstraintRegion from="372" to="381" loc="O" subId="17433127" subSource="5y79_B"/>
      <ConstraintRegion from="382" to="399" loc="H" subId="17433130" subSource="5y79_B"/>
      <ConstraintRegion from="400" to="404" loc="I" subId="17433133" subSource="5y79_B"/>
    </Constraint>
  </Constraints>
</HtpItem>
