<?xml version="1.0" encoding="UTF-8"?>
<HtpItem id="F8WD50_HUMAN" transmembrane="yes" evidence="3D">
  <Name>Solute carrier family 26 member 5 </Name>
  <CrossRef>
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      <Chain id="A"/>
      <Chain id="B"/>
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      <Chain id="A"/>
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    </PDBTM>
    <PDBTM id="7lh2">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7lh3">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7s9a">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7s9d">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7s9e">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7s9b">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7s9c">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7s8x">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="8uc1">
      <Chain id="A"/>
      <Chain id="B"/>
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    <PDBTM id="7sun">
      <Chain id="A"/>
      <Chain id="B"/>
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    <PDBTM id="7xuh">
      <Chain id="A"/>
      <Chain id="B"/>
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      <Chain id="A"/>
      <Chain id="B"/>
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    <PDBTM id="7wk1">
      <Chain id="A"/>
      <Chain id="B"/>
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      <Chain id="A"/>
      <Chain id="B"/>
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      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7wl9">
      <Chain id="A"/>
      <Chain id="B"/>
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    <PDBTM id="7wla">
      <Chain id="A"/>
      <Chain id="B"/>
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    <PDBTM id="7wk7">
      <Chain id="A"/>
      <Chain id="B"/>
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    <PDBTM id="8hzn">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7wle">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7xul">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="8iet">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7v75">
      <Chain id="A"/>
      <Chain id="B"/>
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    <PDBTM id="7v73">
      <Chain id="A"/>
      <Chain id="B"/>
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    <PDBTM id="7v74">
      <Chain id="A"/>
      <Chain id="B"/>
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    <PDBTM id="6rtc">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="6rtf">
      <Chain id="A"/>
      <Chain id="B"/>
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      <Chain id="A"/>
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      <Chain id="A"/>
      <Chain id="B"/>
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      <Chain id="C"/>
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      <Chain id="C"/>
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      <Chain id="A"/>
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      <Chain id="A"/>
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      <Chain id="B"/>
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      <Chain id="B"/>
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      <Chain id="A"/>
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      <Chain id="A"/>
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      <Chain id="C"/>
      <Chain id="D"/>
    </PDBTM>
    <TOPDB id="S26A5_MERUN">
      <Alignment>
        <CrossRefSeq>MDHAEENEIPVATQKYHVERPIFSHPVLQERLHVKDKVSESIGDKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYST</CrossRefSeq>
        <OrigSeq>MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYAS</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="S26A5_RAT">
      <Alignment>
        <CrossRefSeq>MDHAEENEIPAETQKYLVERPIFSHPVLQERLHVKDKVTDSIGDKLKQAFTCTPKKVRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYST</CrossRefSeq>
        <OrigSeq>MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYAS</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="S26A3_HUMAN">
      <Alignment>
        <CrossRefSeq>IEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIF</CrossRefSeq>
        <OrigSeq>ILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIG----GVAVRLVPDDIVIPGGVNATNGTE---ARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVV</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="S26A6_HUMAN">
      <Alignment>
        <CrossRefSeq>TQAMDLRRRDYHMERPLLNQEHLEE-LGRWGSAPRT--HQWRTWLQCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQAL-----NDSMINETARDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYT</CrossRefSeq>
        <OrigSeq>ENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYA</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="S26A7_HUMAN">
      <Alignment>
        <CrossRefSeq>KRKKKSMLWSKMHTPQC--EDIIQWCRRRLPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAIIYAIFGMGHHVATGTFALTSLISANAVERIVPQNMQNLTTQSNTSVLGLSDFEMQRIHVAAAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYISGPLGFFY</CrossRefSeq>
        <OrigSeq>DKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDD--IVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVY</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="SUL2_YEAST">
      <Alignment>
        <CrossRefSeq>SVSQFEETTVSLKEYYDHSIRSHLTVKGACS------YLKSVFPIINWLPHYNFS-WFTADLIAGITIGCVLVPQSMSYAQVATLPAQYGLYSSFIGAYSYSFFATSKDVCIGPVAVMSLQTAKVIADVTAK-----------YPDGDSAITGPVIATTLALLCGIISAAVGFLRLGFLVELISLNAVAGFMTGSAFNILWGQVPALMGYN</CrossRefSeq>
        <OrigSeq>SHPVLQERLHT-KDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVK</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="SULX_YEAST">
      <Alignment>
        <CrossRefSeq>NTVFETLPYYLPCFSWLPEYTFNK-LWGDVIAGISVASFQIPLALSYTTSIAHVPPLCGLYSLAISPFVYGILGSVPQMIVGPESAISLVVGQAVESITLHKENVSL---------------IDISTVITFVSGTILLFSGISRFGFLGNVLSKALLRGFISSVGLVMIINSL</CrossRefSeq>
        <OrigSeq>KKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAM-LAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSML</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="DAUA_ECO57">
      <Alignment>
        <CrossRefSeq>WKEKYTAARFTR-DLIAGITVGIIAIPLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGLAGLLV-----------------------ATLLSGIFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM</CrossRefSeq>
        <OrigSeq>WLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKT</OrigSeq>
      </Alignment>
    </TOPDB>
  </CrossRef>
  <Sequence Length="248" CheckSum="cf12551751c725ea088db73fe5aba689">
    <Seq>
      MDHAEENEIL AATQRYYVER PIFSHPVLQE RLHTKDKVPD SIADKLKQAF
      TCTPKKIRNI IYMFLPITKW LPAYKFKEYV LGDLVSGIST GVLQLPQGLA
      FAMLAAVPPI FGLYSSFYPV IMYCFLGTSR HISIGPFAVI SLMIGGVAVR
      LVPDDIVIPG GVNATNGTEA RDALRVKVAM SVTLLSGIIQ FCLGVCRFGF
      VAIYLTEPLV RGFTTAAAVH VFTSMLKYLF GVKTKRYSGI FSVVYASG
    </Seq>
  </Sequence>
  <Topology numTm="5" reliability="94.69">
    <Region from="1" to="83" loc="I"/>
    <Region from="84" to="104" loc="M"/>
    <Region from="105" to="109" loc="O"/>
    <Region from="110" to="126" loc="M"/>
    <Region from="127" to="131" loc="I"/>
    <Region from="132" to="145" loc="M"/>
    <Region from="146" to="178" loc="O"/>
    <Region from="179" to="195" loc="M"/>
    <Region from="196" to="211" loc="I"/>
    <Region from="212" to="226" loc="M"/>
    <Region from="227" to="236" loc="O"/>
    <Region from="237" to="247" loc="L"/>
    <Region from="248" to="248" loc="O"/>
  </Topology>
  <Predictions>
    <Prediction name="Hmmtop">
      <Region from="1" to="59" loc="I"/>
      <Region from="60" to="73" loc="M"/>
      <Region from="74" to="79" loc="O"/>
      <Region from="80" to="93" loc="M"/>
      <Region from="94" to="98" loc="I"/>
      <Region from="99" to="126" loc="M"/>
      <Region from="127" to="131" loc="O"/>
      <Region from="132" to="149" loc="M"/>
      <Region from="150" to="177" loc="I"/>
      <Region from="178" to="203" loc="M"/>
      <Region from="204" to="248" loc="O"/>
    </Prediction>
    <Prediction name="Memsat">
      <Region from="1" to="82" loc="I"/>
      <Region from="83" to="101" loc="M"/>
      <Region from="102" to="104" loc="O"/>
      <Region from="105" to="126" loc="M"/>
      <Region from="127" to="132" loc="I"/>
      <Region from="133" to="148" loc="M"/>
      <Region from="149" to="176" loc="O"/>
      <Region from="177" to="205" loc="M"/>
      <Region from="206" to="208" loc="I"/>
      <Region from="209" to="229" loc="M"/>
      <Region from="230" to="248" loc="O"/>
    </Prediction>
    <Prediction name="Octopus">
      <Region from="1" to="51" loc="O"/>
      <Region from="52" to="72" loc="M"/>
      <Region from="73" to="80" loc="I"/>
      <Region from="81" to="101" loc="M"/>
      <Region from="102" to="103" loc="O"/>
      <Region from="104" to="124" loc="M"/>
      <Region from="125" to="130" loc="I"/>
      <Region from="131" to="151" loc="M"/>
      <Region from="152" to="175" loc="O"/>
      <Region from="176" to="190" loc="M"/>
      <Region from="191" to="191" loc="I"/>
      <Region from="192" to="206" loc="M"/>
      <Region from="207" to="207" loc="O"/>
      <Region from="208" to="228" loc="M"/>
      <Region from="229" to="248" loc="I"/>
    </Prediction>
    <Prediction name="Philius">
      <Region from="1" to="97" loc="I"/>
      <Region from="98" to="121" loc="M"/>
      <Region from="122" to="131" loc="O"/>
      <Region from="132" to="152" loc="M"/>
      <Region from="153" to="179" loc="I"/>
      <Region from="180" to="201" loc="M"/>
      <Region from="202" to="209" loc="O"/>
      <Region from="210" to="231" loc="M"/>
      <Region from="232" to="248" loc="I"/>
    </Prediction>
    <Prediction name="Phobius">
      <Region from="1" to="98" loc="I"/>
      <Region from="99" to="121" loc="M"/>
      <Region from="122" to="132" loc="O"/>
      <Region from="133" to="152" loc="M"/>
      <Region from="153" to="177" loc="I"/>
      <Region from="178" to="203" loc="M"/>
      <Region from="204" to="208" loc="O"/>
      <Region from="209" to="230" loc="M"/>
      <Region from="231" to="248" loc="I"/>
    </Prediction>
    <Prediction name="Pro">
      <Region from="1" to="83" loc="I"/>
      <Region from="84" to="104" loc="M"/>
      <Region from="105" to="108" loc="O"/>
      <Region from="109" to="129" loc="M"/>
      <Region from="130" to="131" loc="I"/>
      <Region from="132" to="152" loc="M"/>
      <Region from="153" to="172" loc="O"/>
      <Region from="173" to="193" loc="M"/>
      <Region from="194" to="208" loc="I"/>
      <Region from="209" to="229" loc="M"/>
      <Region from="230" to="248" loc="O"/>
    </Prediction>
    <Prediction name="Prodiv">
      <Region from="1" to="83" loc="I"/>
      <Region from="84" to="104" loc="M"/>
      <Region from="105" to="124" loc="O"/>
      <Region from="125" to="145" loc="M"/>
      <Region from="146" to="179" loc="I"/>
      <Region from="180" to="200" loc="M"/>
      <Region from="201" to="210" loc="O"/>
      <Region from="211" to="231" loc="M"/>
      <Region from="232" to="248" loc="I"/>
    </Prediction>
    <Prediction name="Scampi2">
      <Region from="1" to="97" loc="I"/>
      <Region from="98" to="118" loc="M"/>
      <Region from="119" to="131" loc="O"/>
      <Region from="132" to="151" loc="M"/>
      <Region from="152" to="181" loc="I"/>
      <Region from="182" to="201" loc="M"/>
      <Region from="202" to="208" loc="O"/>
      <Region from="209" to="229" loc="M"/>
      <Region from="230" to="248" loc="I"/>
    </Prediction>
    <Prediction name="ScampiMsa2">
      <Region from="1" to="55" loc="I"/>
      <Region from="56" to="76" loc="M"/>
      <Region from="77" to="83" loc="O"/>
      <Region from="84" to="104" loc="M"/>
      <Region from="105" to="109" loc="I"/>
      <Region from="110" to="130" loc="M"/>
      <Region from="131" to="131" loc="O"/>
      <Region from="132" to="152" loc="M"/>
      <Region from="153" to="177" loc="I"/>
      <Region from="178" to="198" loc="M"/>
      <Region from="199" to="208" loc="O"/>
      <Region from="209" to="229" loc="M"/>
      <Region from="230" to="248" loc="I"/>
    </Prediction>
    <Prediction name="SignalP">
      <Region/>
    </Prediction>
    <Prediction name="TMHMM">
      <Region from="1" to="98" loc="I"/>
      <Region from="99" to="121" loc="M"/>
      <Region from="122" to="130" loc="O"/>
      <Region from="131" to="153" loc="M"/>
      <Region from="154" to="181" loc="I"/>
      <Region from="182" to="204" loc="M"/>
      <Region from="205" to="208" loc="O"/>
      <Region from="209" to="231" loc="M"/>
      <Region from="232" to="248" loc="I"/>
    </Prediction>
  </Predictions>
  <Constraints>
    <Constraint source="TOPDB" sourceId="7v75_A">
      <ConstraintRegion from="58" to="84" loc="I" subId="17357641" subSource="7v75_A"/>
      <ConstraintRegion from="85" to="105" loc="H" subId="17357643" subSource="7v75_A"/>
      <ConstraintRegion from="106" to="111" loc="O" subId="17357645" subSource="7v75_A"/>
      <ConstraintRegion from="112" to="127" loc="H" subId="17357646" subSource="7v75_A"/>
      <ConstraintRegion from="128" to="132" loc="I" subId="17357648" subSource="7v75_A"/>
      <ConstraintRegion from="133" to="147" loc="H" subId="17357650" subSource="7v75_A"/>
      <ConstraintRegion from="148" to="155" loc="O" subId="17357652" subSource="7v75_A"/>
      <ConstraintRegion from="166" to="179" loc="O" subId="17357656" subSource="7v75_A"/>
      <ConstraintRegion from="180" to="196" loc="H" subId="17357658" subSource="7v75_A"/>
      <ConstraintRegion from="197" to="210" loc="I" subId="17357660" subSource="7v75_A"/>
      <ConstraintRegion from="211" to="226" loc="H" subId="17357662" subSource="7v75_A"/>
      <ConstraintRegion from="227" to="264" loc="O" subId="17357663" subSource="7v75_A"/>
      <ConstraintRegion from="265" to="279" loc="H" subId="17357665" subSource="7v75_A"/>
      <ConstraintRegion from="280" to="288" loc="I" subId="17357667" subSource="7v75_A"/>
      <ConstraintRegion from="289" to="300" loc="H" subId="17357668" subSource="7v75_A"/>
      <ConstraintRegion from="301" to="339" loc="O" subId="17357670" subSource="7v75_A"/>
      <ConstraintRegion from="340" to="355" loc="H" subId="17357672" subSource="7v75_A"/>
      <ConstraintRegion from="356" to="374" loc="I" subId="17357674" subSource="7v75_A"/>
      <ConstraintRegion from="375" to="389" loc="H" subId="17357676" subSource="7v75_A"/>
      <ConstraintRegion from="390" to="390" loc="O" subId="17357677" subSource="7v75_A"/>
      <ConstraintRegion from="391" to="403" loc="H" subId="17357678" subSource="7v75_A"/>
      <ConstraintRegion from="404" to="411" loc="I" subId="17357680" subSource="7v75_A"/>
      <ConstraintRegion from="412" to="428" loc="H" subId="17357681" subSource="7v75_A"/>
      <ConstraintRegion from="429" to="438" loc="O" subId="17357683" subSource="7v75_A"/>
      <ConstraintRegion from="439" to="455" loc="H" subId="17357685" subSource="7v75_A"/>
      <ConstraintRegion from="456" to="473" loc="I" subId="17357686" subSource="7v75_A"/>
      <ConstraintRegion from="474" to="494" loc="L" subId="17357687" subSource="7v75_A"/>
      <ConstraintRegion from="495" to="583" loc="I" subId="17357689" subSource="7v75_A"/>
      <ConstraintRegion from="634" to="722" loc="I" subId="17357691" subSource="7v75_A"/>
      <ConstraintRegion from="58" to="84" loc="I" subId="17357694" subSource="7v75_B"/>
      <ConstraintRegion from="85" to="105" loc="H" subId="17357695" subSource="7v75_B"/>
      <ConstraintRegion from="106" to="111" loc="O" subId="17357696" subSource="7v75_B"/>
      <ConstraintRegion from="112" to="127" loc="H" subId="17357697" subSource="7v75_B"/>
      <ConstraintRegion from="128" to="132" loc="I" subId="17357698" subSource="7v75_B"/>
      <ConstraintRegion from="133" to="147" loc="H" subId="17357699" subSource="7v75_B"/>
      <ConstraintRegion from="148" to="155" loc="O" subId="17357700" subSource="7v75_B"/>
      <ConstraintRegion from="166" to="179" loc="O" subId="17357702" subSource="7v75_B"/>
      <ConstraintRegion from="180" to="196" loc="H" subId="17357704" subSource="7v75_B"/>
      <ConstraintRegion from="197" to="210" loc="I" subId="17357706" subSource="7v75_B"/>
      <ConstraintRegion from="211" to="226" loc="H" subId="17357708" subSource="7v75_B"/>
      <ConstraintRegion from="227" to="264" loc="O" subId="17357710" subSource="7v75_B"/>
      <ConstraintRegion from="265" to="279" loc="H" subId="17357712" subSource="7v75_B"/>
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    </Constraint>
  </Constraints>
</HtpItem>
