<?xml version="1.0" encoding="UTF-8"?>
<HtpItem id="H0Y2X7_HUMAN" transmembrane="yes" evidence="3D">
  <Name>Solute carrier family 7 member 8 </Name>
  <CrossRef>
    <PDBTM id="7ccs">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7dsk">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7dsl">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7dsn">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="8xpu">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7dsq">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="8ida">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="6irs">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="6irt">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="6li9">
      <Chain id="B"/>
      <Chain id="D"/>
    </PDBTM>
    <PDBTM id="6lid">
      <Chain id="B"/>
      <Chain id="D"/>
    </PDBTM>
    <PDBTM id="7b00">
      <Chain id="A"/>
    </PDBTM>
    <PDBTM id="7cmh">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="8a6l">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7cmi">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7p9u">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7p9v">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7epz">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7nf6">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="7nf8">
      <Chain id="B"/>
      <Chain id="E"/>
    </PDBTM>
    <PDBTM id="6jmq">
      <Chain id="A"/>
    </PDBTM>
    <PDBTM id="6yup">
      <Chain id="D"/>
      <Chain id="E"/>
    </PDBTM>
    <PDBTM id="6yv1">
      <Chain id="A"/>
    </PDBTM>
    <PDBTM id="8j8m">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="8j8l">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="8wny">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="8wns">
      <Chain id="B"/>
    </PDBTM>
    <PDBTM id="8qey">
      <Chain id="A"/>
    </PDBTM>
    <PDBTM id="8wnt">
      <Chain id="B"/>
    </PDBTM>
    <TOPDB id="XCT_HUMAN">
      <Alignment>
        <CrossRefSeq>IQIFLTFCKLTAILIIIVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVT--EEVENPEKTIPLAICISMAIVTIGY-VLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFK</CrossRefSeq>
        <OrigSeq>LQEHSQPSQLLCTLLLC-----WCVLGRERPFRKAQSTSSP-LEGVPRFLKRLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFA--------YGGWNFLNYVTEELVDPYKLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIK</OrigSeq>
      </Alignment>
    </TOPDB>
  </CrossRef>
  <Sequence Length="230" CheckSum="89660e3ef21cff1b4538c994a880ccfd">
    <Seq>
      XCLQEHSQPS QLLCTLLLCW CVLGRERPFR KAQSTSSPLE GVPRFLKRLL
      LTWVNCSSVR WATRVQDIFT AGKLLALALI IIMGIVQICK GEYFWLEPKN
      AFENFQEPDI GLVALAFLQG SFAYGGWNFL NYVTEELVDP YKLFFAGARE
      GHLPSVLAMI HVKRCTPIPA LLFTCISTLL MLVTSDMYTL INYVGFINYL
      FYGVTVAGQI VLRWKKPDIP RPIKPLPYQG 
    </Seq>
  </Sequence>
  <Topology numTm="5" reliability="72.58">
    <Region from="1" to="9" loc="O"/>
    <Region from="10" to="24" loc="M"/>
    <Region from="25" to="68" loc="I"/>
    <Region from="69" to="88" loc="M"/>
    <Region from="89" to="109" loc="O"/>
    <Region from="110" to="129" loc="M"/>
    <Region from="130" to="164" loc="I"/>
    <Region from="165" to="184" loc="M"/>
    <Region from="185" to="192" loc="O"/>
    <Region from="193" to="212" loc="M"/>
    <Region from="213" to="230" loc="I"/>
  </Topology>
  <Predictions>
    <Prediction name="Hmmtop">
      <Region from="1" to="11" loc="O"/>
      <Region from="12" to="24" loc="M"/>
      <Region from="25" to="73" loc="I"/>
      <Region from="74" to="86" loc="M"/>
      <Region from="87" to="109" loc="O"/>
      <Region from="110" to="126" loc="M"/>
      <Region from="127" to="167" loc="I"/>
      <Region from="168" to="183" loc="M"/>
      <Region from="184" to="193" loc="O"/>
      <Region from="194" to="208" loc="M"/>
      <Region from="209" to="230" loc="I"/>
    </Prediction>
    <Prediction name="Memsat">
      <Region from="1" to="41" loc="O"/>
      <Region from="42" to="63" loc="M"/>
      <Region from="64" to="67" loc="I"/>
      <Region from="68" to="89" loc="M"/>
      <Region from="90" to="112" loc="O"/>
      <Region from="113" to="133" loc="M"/>
      <Region from="134" to="165" loc="I"/>
      <Region from="166" to="185" loc="M"/>
      <Region from="186" to="188" loc="O"/>
      <Region from="189" to="212" loc="M"/>
      <Region from="213" to="230" loc="I"/>
    </Prediction>
    <Prediction name="Octopus">
      <Region from="1" to="3" loc="I"/>
      <Region from="4" to="24" loc="M"/>
      <Region from="25" to="50" loc="O"/>
      <Region from="51" to="71" loc="M"/>
      <Region from="72" to="72" loc="I"/>
      <Region from="73" to="93" loc="M"/>
      <Region from="94" to="109" loc="O"/>
      <Region from="110" to="130" loc="M"/>
      <Region from="131" to="166" loc="I"/>
      <Region from="167" to="187" loc="M"/>
      <Region from="188" to="192" loc="O"/>
      <Region from="193" to="213" loc="M"/>
      <Region from="214" to="230" loc="I"/>
    </Prediction>
    <Prediction name="Philius">
      <Region from="1" to="68" loc="I"/>
      <Region from="69" to="89" loc="M"/>
      <Region from="90" to="109" loc="O"/>
      <Region from="110" to="130" loc="M"/>
      <Region from="131" to="164" loc="I"/>
      <Region from="165" to="185" loc="M"/>
      <Region from="186" to="192" loc="O"/>
      <Region from="193" to="214" loc="M"/>
      <Region from="215" to="230" loc="I"/>
    </Prediction>
    <Prediction name="Phobius">
      <Region from="1" to="5" loc="O"/>
      <Region from="6" to="24" loc="M"/>
      <Region from="25" to="44" loc="I"/>
      <Region from="45" to="62" loc="M"/>
      <Region from="63" to="67" loc="O"/>
      <Region from="68" to="89" loc="M"/>
      <Region from="90" to="164" loc="I"/>
      <Region from="165" to="184" loc="M"/>
      <Region from="185" to="189" loc="O"/>
      <Region from="190" to="212" loc="M"/>
      <Region from="213" to="230" loc="I"/>
    </Prediction>
    <Prediction name="Pro">
      <Region from="1" to="5" loc="I"/>
      <Region from="6" to="26" loc="M"/>
      <Region from="27" to="41" loc="O"/>
      <Region from="42" to="62" loc="M"/>
      <Region from="63" to="82" loc="I"/>
      <Region from="83" to="103" loc="M"/>
      <Region from="104" to="123" loc="O"/>
      <Region from="124" to="144" loc="M"/>
      <Region from="145" to="164" loc="I"/>
      <Region from="165" to="185" loc="M"/>
      <Region from="186" to="189" loc="O"/>
      <Region from="190" to="210" loc="M"/>
      <Region from="211" to="230" loc="I"/>
    </Prediction>
    <Prediction name="Prodiv">
      <Region from="1" to="6" loc="I"/>
      <Region from="7" to="27" loc="M"/>
      <Region from="28" to="43" loc="O"/>
      <Region from="44" to="64" loc="M"/>
      <Region from="65" to="84" loc="I"/>
      <Region from="85" to="105" loc="M"/>
      <Region from="106" to="126" loc="O"/>
      <Region from="127" to="147" loc="M"/>
      <Region from="148" to="167" loc="I"/>
      <Region from="168" to="188" loc="M"/>
      <Region from="189" to="192" loc="O"/>
      <Region from="193" to="213" loc="M"/>
      <Region from="214" to="230" loc="I"/>
    </Prediction>
    <Prediction name="Scampi2">
      <Region from="1" to="8" loc="O"/>
      <Region from="9" to="28" loc="M"/>
      <Region from="29" to="44" loc="I"/>
      <Region from="45" to="64" loc="M"/>
      <Region from="65" to="68" loc="O"/>
      <Region from="69" to="88" loc="M"/>
      <Region from="89" to="109" loc="I"/>
      <Region from="110" to="129" loc="M"/>
      <Region from="130" to="169" loc="O"/>
      <Region from="170" to="190" loc="M"/>
      <Region from="191" to="230" loc="I"/>
    </Prediction>
    <Prediction name="ScampiMsa2">
      <Region from="1" to="8" loc="O"/>
      <Region from="9" to="29" loc="M"/>
      <Region from="30" to="68" loc="I"/>
      <Region from="69" to="89" loc="M"/>
      <Region from="90" to="109" loc="O"/>
      <Region from="110" to="130" loc="M"/>
      <Region from="131" to="164" loc="I"/>
      <Region from="165" to="185" loc="M"/>
      <Region from="186" to="193" loc="O"/>
      <Region from="194" to="214" loc="M"/>
      <Region from="215" to="230" loc="I"/>
    </Prediction>
    <Prediction name="SignalP">
      <Region/>
    </Prediction>
    <Prediction name="TMHMM">
      <Region from="1" to="73" loc="I"/>
      <Region from="74" to="96" loc="M"/>
      <Region from="97" to="110" loc="O"/>
      <Region from="111" to="133" loc="M"/>
      <Region from="134" to="167" loc="I"/>
      <Region from="168" to="185" loc="M"/>
      <Region from="186" to="189" loc="O"/>
      <Region from="190" to="212" loc="M"/>
      <Region from="213" to="230" loc="I"/>
    </Prediction>
  </Predictions>
  <Constraints>
    <Constraint source="TOPDB" sourceId="7nf6_B">
      <ConstraintRegion from="29" to="36" loc="I" subId="17205477" subSource="7nf6_B"/>
      <ConstraintRegion from="37" to="56" loc="H" subId="17205479" subSource="7nf6_B"/>
      <ConstraintRegion from="57" to="64" loc="O" subId="17205482" subSource="7nf6_B"/>
      <ConstraintRegion from="65" to="81" loc="H" subId="17205485" subSource="7nf6_B"/>
      <ConstraintRegion from="82" to="114" loc="I" subId="17205487" subSource="7nf6_B"/>
      <ConstraintRegion from="115" to="137" loc="H" subId="17205490" subSource="7nf6_B"/>
      <ConstraintRegion from="138" to="149" loc="O" subId="17205492" subSource="7nf6_B"/>
      <ConstraintRegion from="150" to="168" loc="H" subId="17205494" subSource="7nf6_B"/>
      <ConstraintRegion from="169" to="172" loc="I" subId="17205497" subSource="7nf6_B"/>
      <ConstraintRegion from="173" to="197" loc="H" subId="17205500" subSource="7nf6_B"/>
      <ConstraintRegion from="198" to="216" loc="O" subId="17205503" subSource="7nf6_B"/>
      <ConstraintRegion from="217" to="237" loc="H" subId="17205507" subSource="7nf6_B"/>
      <ConstraintRegion from="238" to="256" loc="I" subId="17205510" subSource="7nf6_B"/>
      <ConstraintRegion from="257" to="274" loc="H" subId="17205513" subSource="7nf6_B"/>
      <ConstraintRegion from="275" to="303" loc="O" subId="17205516" subSource="7nf6_B"/>
      <ConstraintRegion from="304" to="322" loc="H" subId="17205519" subSource="7nf6_B"/>
      <ConstraintRegion from="323" to="355" loc="I" subId="17205522" subSource="7nf6_B"/>
      <ConstraintRegion from="356" to="372" loc="H" subId="17205525" subSource="7nf6_B"/>
      <ConstraintRegion from="373" to="373" loc="O" subId="17205528" subSource="7nf6_B"/>
      <ConstraintRegion from="374" to="388" loc="H" subId="17205531" subSource="7nf6_B"/>
      <ConstraintRegion from="389" to="412" loc="I" subId="17205534" subSource="7nf6_B"/>
      <ConstraintRegion from="413" to="433" loc="H" subId="17205537" subSource="7nf6_B"/>
      <ConstraintRegion from="434" to="434" loc="O" subId="17205541" subSource="7nf6_B"/>
      <ConstraintRegion from="435" to="449" loc="H" subId="17205543" subSource="7nf6_B"/>
      <ConstraintRegion from="450" to="483" loc="I" subId="17205545" subSource="7nf6_B"/>
      <ConstraintRegion from="29" to="32" loc="I" subId="17205663" subSource="7nf8_B"/>
      <ConstraintRegion from="33" to="48" loc="H" subId="17205666" subSource="7nf8_B"/>
      <ConstraintRegion from="49" to="69" loc="O" subId="17205669" subSource="7nf8_B"/>
      <ConstraintRegion from="70" to="83" loc="H" subId="17205672" subSource="7nf8_B"/>
      <ConstraintRegion from="84" to="114" loc="I" subId="17205675" subSource="7nf8_B"/>
      <ConstraintRegion from="115" to="130" loc="H" subId="17205678" subSource="7nf8_B"/>
      <ConstraintRegion from="131" to="155" loc="O" subId="17205681" subSource="7nf8_B"/>
      <ConstraintRegion from="156" to="170" loc="H" subId="17205684" subSource="7nf8_B"/>
      <ConstraintRegion from="171" to="171" loc="I" subId="17205687" subSource="7nf8_B"/>
      <ConstraintRegion from="172" to="186" loc="H" subId="17205690" subSource="7nf8_B"/>
      <ConstraintRegion from="187" to="225" loc="O" subId="17205693" subSource="7nf8_B"/>
      <ConstraintRegion from="226" to="238" loc="H" subId="17205696" subSource="7nf8_B"/>
      <ConstraintRegion from="239" to="253" loc="I" subId="17205698" subSource="7nf8_B"/>
      <ConstraintRegion from="254" to="267" loc="H" subId="17205701" subSource="7nf8_B"/>
      <ConstraintRegion from="268" to="311" loc="O" subId="17205704" subSource="7nf8_B"/>
      <ConstraintRegion from="312" to="324" loc="H" subId="17205707" subSource="7nf8_B"/>
      <ConstraintRegion from="325" to="352" loc="I" subId="17205710" subSource="7nf8_B"/>
      <ConstraintRegion from="353" to="367" loc="H" subId="17205713" subSource="7nf8_B"/>
      <ConstraintRegion from="368" to="374" loc="O" subId="17205716" subSource="7nf8_B"/>
      <ConstraintRegion from="375" to="391" loc="H" subId="17205717" subSource="7nf8_B"/>
      <ConstraintRegion from="392" to="411" loc="I" subId="17205718" subSource="7nf8_B"/>
      <ConstraintRegion from="412" to="430" loc="H" subId="17205719" subSource="7nf8_B"/>
      <ConstraintRegion from="431" to="435" loc="O" subId="17205720" subSource="7nf8_B"/>
      <ConstraintRegion from="436" to="449" loc="H" subId="17205721" subSource="7nf8_B"/>
      <ConstraintRegion from="450" to="483" loc="I" subId="17205722" subSource="7nf8_B"/>
      <ConstraintRegion from="29" to="32" loc="I" subId="17205729" subSource="7nf8_E"/>
      <ConstraintRegion from="33" to="48" loc="H" subId="17205730" subSource="7nf8_E"/>
      <ConstraintRegion from="49" to="69" loc="O" subId="17205731" subSource="7nf8_E"/>
      <ConstraintRegion from="70" to="83" loc="H" subId="17205732" subSource="7nf8_E"/>
      <ConstraintRegion from="84" to="114" loc="I" subId="17205733" subSource="7nf8_E"/>
      <ConstraintRegion from="115" to="130" loc="H" subId="17205734" subSource="7nf8_E"/>
      <ConstraintRegion from="131" to="155" loc="O" subId="17205735" subSource="7nf8_E"/>
      <ConstraintRegion from="156" to="170" loc="H" subId="17205736" subSource="7nf8_E"/>
      <ConstraintRegion from="171" to="171" loc="I" subId="17205737" subSource="7nf8_E"/>
      <ConstraintRegion from="172" to="186" loc="H" subId="17205738" subSource="7nf8_E"/>
      <ConstraintRegion from="187" to="225" loc="O" subId="17205739" subSource="7nf8_E"/>
      <ConstraintRegion from="226" to="238" loc="H" subId="17205740" subSource="7nf8_E"/>
      <ConstraintRegion from="239" to="253" loc="I" subId="17205741" subSource="7nf8_E"/>
      <ConstraintRegion from="254" to="267" loc="H" subId="17205742" subSource="7nf8_E"/>
      <ConstraintRegion from="268" to="311" loc="O" subId="17205743" subSource="7nf8_E"/>
      <ConstraintRegion from="312" to="324" loc="H" subId="17205744" subSource="7nf8_E"/>
      <ConstraintRegion from="325" to="352" loc="I" subId="17205745" subSource="7nf8_E"/>
      <ConstraintRegion from="353" to="367" loc="H" subId="17205746" subSource="7nf8_E"/>
      <ConstraintRegion from="368" to="374" loc="O" subId="17205747" subSource="7nf8_E"/>
      <ConstraintRegion from="375" to="391" loc="H" subId="17205748" subSource="7nf8_E"/>
      <ConstraintRegion from="392" to="411" loc="I" subId="17205749" subSource="7nf8_E"/>
      <ConstraintRegion from="412" to="430" loc="H" subId="17205750" subSource="7nf8_E"/>
      <ConstraintRegion from="431" to="435" loc="O" subId="17205751" subSource="7nf8_E"/>
      <ConstraintRegion from="436" to="449" loc="H" subId="17205752" subSource="7nf8_E"/>
      <ConstraintRegion from="450" to="483" loc="I" subId="17205753" subSource="7nf8_E"/>
    </Constraint>
  </Constraints>
</HtpItem>
