<?xml version="1.0" encoding="UTF-8"?>
<HtpItem id="H0YBA4_HUMAN" transmembrane="yes" evidence="Exists">
  <Name>HECT-type E3 ubiquitin transferase </Name>
  <CrossRef>
    <PDBTM id="4lcd">
      <Chain id="A"/>
      <Chain id="B"/>
    </PDBTM>
  </CrossRef>
  <Sequence Length="232" CheckSum="b46be147e6c16a0625db02da4284b66f">
    <Seq>
      XGGPQIAYER GFRWKLAHFR YLCQSNALPS HVKINVSRQT LFEDSFQQIM
      ALKPYDLRRR LYVIFRGEEG LDYGGLARNI LRSSLMSGKF SSIMSLNIFS
      VPFVPFFFRN ISHGEWFFLL SHEVLNPMYC LFEYAGKNNY CLQINPASTI
      NPDHLSYFCF IGRFIAMALF HGKFIDTGFS LPFYKRMLSK KLTIKDLESI
      DTEFYNSLIW IRDNNIEECG LEMYFSVDME IL
    </Seq>
  </Sequence>
  <Topology numTm="2" reliability="76.16">
    <Region from="1" to="97" loc="I"/>
    <Region from="98" to="109" loc="M"/>
    <Region from="110" to="157" loc="O"/>
    <Region from="158" to="175" loc="M"/>
    <Region from="176" to="232" loc="I"/>
  </Topology>
  <Predictions>
    <Prediction name="Hmmtop">
      <Region from="1" to="92" loc="I"/>
      <Region from="93" to="113" loc="M"/>
      <Region from="114" to="232" loc="O"/>
    </Prediction>
    <Prediction name="Memsat">
      <Region from="1" to="157" loc="I"/>
      <Region from="158" to="175" loc="M"/>
      <Region from="176" to="232" loc="O"/>
    </Prediction>
    <Prediction name="Octopus">
      <Region from="1" to="105" loc="I"/>
      <Region from="106" to="126" loc="M"/>
      <Region from="127" to="156" loc="O"/>
      <Region from="157" to="177" loc="M"/>
      <Region from="178" to="232" loc="I"/>
    </Prediction>
    <Prediction name="Philius">
      <Region from="1" to="87" loc="I"/>
      <Region from="88" to="108" loc="M"/>
      <Region from="109" to="158" loc="O"/>
      <Region from="159" to="175" loc="M"/>
      <Region from="176" to="232" loc="I"/>
    </Prediction>
    <Prediction name="Phobius">
      <Region from="1" to="89" loc="I"/>
      <Region from="90" to="108" loc="M"/>
      <Region from="109" to="154" loc="O"/>
      <Region from="155" to="175" loc="M"/>
      <Region from="176" to="232" loc="I"/>
    </Prediction>
    <Prediction name="Pro">
      <Region/>
    </Prediction>
    <Prediction name="Prodiv">
      <Region from="1" to="153" loc="I"/>
      <Region from="154" to="174" loc="M"/>
      <Region from="175" to="232" loc="O"/>
    </Prediction>
    <Prediction name="Scampi2">
      <Region/>
    </Prediction>
    <Prediction name="ScampiMsa2">
      <Region/>
    </Prediction>
    <Prediction name="SignalP">
      <Region/>
    </Prediction>
    <Prediction name="TMHMM">
      <Region/>
    </Prediction>
  </Predictions>
  <Constraints/>
</HtpItem>
