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      <Alignment>
        <CrossRefSeq>SSFKRGSIKSSTSGSQKGQKAWIEKTFCKRECIFVIPSTKDPNRCCCGQLTNQHIPPLPSGAPSTTGEDTKQADTQSGKWSVSKHTQSYPTDSYGILEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQSFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVVSHVGDALKDHSSKSRG</CrossRefSeq>
        <OrigSeq>SSFKRGSLKSSTSGSQKGQKSWIEKTFCKRECIFVIPSMKDSNRCCCGQFTNQHIPPLPSATPSKNEEESKQVETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTAP---CGENLYDEEGKRLP</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="TRPM7_MOUSE">
      <Alignment>
        <CrossRefSeq>SQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAMKYSDVKLGEHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEIILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSS</CrossRefSeq>
        <OrigSeq>GQKSWIEKTFCKRECIFVIPSMKDSNRCC-------------CGQFTNQHIPPLPS-ATPSKNEEESKQVETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTAP---CGENLYDEEGKRL</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="TRPM7_RAT">
      <Alignment>
        <CrossRefSeq>SQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLATKYSDVKLGEHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEIILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSS</CrossRefSeq>
        <OrigSeq>GQKSWIEKTFCKRECIFVIPSMKDSNRCC-------------CGQFTNQHIPPLPS-ATPSKNEEESKQVETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTAP---CGENLYDEEGKRL</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="TRPM8_HUMAN">
      <Alignment>
        <CrossRefSeq>YFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTLRLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFRSVIYEPYLAMFGQVPSDVDGTTYDFAHCTFTGNESKPLCVELDEHNLPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGTVQENNDQVWKFQRYFLVQEYCSRLNIPFPFIVFAYFYMVVKKCFKCCCKEKNMESSVCCF-------KNEDNETLAWEGVMKENYLVKINTKANDTSEEMRHRFRQLDTKLNDLKGLLKEIANKIK</CrossRefSeq>
        <OrigSeq>YPTDSYGVLEFQGGGYSNKAMYIRVSYDTKPD-----SLLHLMVKDWQLELPKLL-ISVHGGLQNFEMQPKLKQV----------------FGKGLIKAAMTTGAWIFTGGVSTAP---CGENLYDEEGKRL-------------PPCI---------PGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIILSHIYIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKRLHEFEEQCVQEHFREKEDEQQSSSDE---RIRVTSERVENMSMRLEEINERET</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="TRPM8_MOUSE">
      <Alignment>
        <CrossRefSeq>YFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTLRLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFRSVIYEPYLAMFGQVPSDVDSTTYDFSHCTFSGNESKPLCVELDEHNLPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGIVQENNDQVWKFQRYFLVQEYCNRLNIPFPFVVFAYFYMVVKKCFKCCCKEKNMESNACCF-------RNEDNETLAWEGVMKENYLVKINTKANDNSEEMRHRFRQLDSKLNDLKSLLKEIANNIK</CrossRefSeq>
        <OrigSeq>YPTDSYGVLEFQGGGYSNKAMYIRVSYDTKPD-----SLLHLMVKDWQLELPKLL-ISVHGGLQNFEMQPKLKQV----------------FGKGLIKAAMTTGAWIFTGGVSTAP---CGENLYDEEGKRL-------------PPCI---------PGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIILSHIYIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKRLHEFEEQCVQEHFREKEDEQQSSSDE---RIRVTSERVENMSMRLEEINERET</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="TRPM4_HUMAN">
      <Alignment>
        <CrossRefSeq>PEKEQSWIPKIFKKKTCTTFIVDSTDPGGTLCQCGRPRTAH--------PAVAMEDAFGAAVV-TVWDSDAHTTEKPTDAYGELDFTGAG-RKHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVA</CrossRefSeq>
        <OrigSeq>QKGQKSWIEKTFCKRECIFVIPSMKDS--NRCCCGQFTNQHIPPLPSATPSKNEEESKQVETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTAP---CGENLYDEEGKRLPPCIPGA</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="TRPC6_HUMAN">
      <Alignment>
        <CrossRefSeq>VEESFKTLFWAIFGLSEVKSVVINYNH---------KFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLFYLLLKLKKWISELFQGHKKGFQEDAEMNKINEEKKLGILGSHEDLSKLSLDKKQVGHNKQPSIRSSEDFHLNSFNNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYEL--LEEKSQNTED-LAELIRELGEKLSMEPNQEETNR</CrossRefSeq>
        <OrigSeq>IKAAMTTGAWIFTGGVSTAPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRP-VLPPPMIILSHIYIIIMRL--------------SGRCRKKREGDQEERDRGLKLFLSDEELKRL-HEFEEQ---------CVQEHFREKEDEQQSSSDERIRVTSERV---ENMSMRLEEINERE-TFMKTSLQTVDLRLAQLEELSNRMVNALENLAGIDRSDLIQARSRASSEC</OrigSeq>
      </Alignment>
    </TOPDB>
  </CrossRef>
  <Sequence Length="757" CheckSum="ea193266107964b0f35b513363338010">
    <Seq>
      MSSFKRGSLK SSTSGSQKGQ KSWIEKTFCK RECIFVIPSM KDSNRCCCGQ
      FTNQHIPPLP SATPSKNEEE SKQVETQPEK WSVAKHTQSY PTDSYGVLEF
      QGGGYSNKAM YIRVSYDTKP DSLLHLMVKD WQLELPKLLI SVHGGLQNFE
      MQPKLKQVFG KGLIKAAMTT GAWIFTGGVS TAPCGENLYD EEGKRLPPCI
      PGAWLTPALM ACYLLVANIL LVNLLIAVFN NTFFEVKSIS NQVWKFQRYQ
      LIMTFHDRPV LPPPMIILSH IYIIIMRLSG RCRKKREGDQ EERDRGLKLF
      LSDEELKRLH EFEEQCVQEH FREKEDEQQS SSDERIRVTS ERVENMSMRL
      EEINERETFM KTSLQTVDLR LAQLEELSNR MVNALENLAG IDRSDLIQAR
      SRASSECEAT YLLRQSSINS ADGYSLYRYH FNGEELLFED TSLSTSPGTG
      VRKKTCSFRI KEEKDVKTHL VPECQNSLHL SLGTSTSATP DGSHLAVDDL
      KNAEESKLGP DIGISKEDDE RQTDSKKEET ISPSLNKTDV IHGQDKSDVQ
      NTQLTVETTN IEGTISYPLE ETKITRYFPD ETINACKTMK SRSFVYSRGR
      KLVGGVNQDV EYSSITDQQL TTEWQCQVQK ITRSHSTDIP YIVSEAAVQA
      EHKEQFADMQ DEHHVAEAIP RIPRLSLTIT DRNGMENLLS VKPDQTLGFP
      SLRSKSLHGH PRNVKSIQGK LDRSGHASSV SSLVIVSGMT AEEKKVKKEK
      ASTETEC
    </Seq>
  </Sequence>
  <Topology numTm="2" reliability="79.35">
    <Region from="1" to="202" loc="I"/>
    <Region from="203" to="229" loc="M"/>
    <Region from="230" to="259" loc="O"/>
    <Region from="260" to="275" loc="M"/>
    <Region from="276" to="757" loc="I"/>
  </Topology>
  <Predictions>
    <Prediction name="Hmmtop">
      <Region from="1" to="264" loc="O"/>
      <Region from="265" to="276" loc="M"/>
      <Region from="277" to="757" loc="I"/>
    </Prediction>
    <Prediction name="Memsat">
      <Region from="1" to="202" loc="I"/>
      <Region from="203" to="230" loc="M"/>
      <Region from="231" to="261" loc="O"/>
      <Region from="262" to="277" loc="M"/>
      <Region from="278" to="757" loc="I"/>
    </Prediction>
    <Prediction name="Octopus">
      <Region from="1" to="138" loc="I"/>
      <Region from="139" to="145" loc="L"/>
      <Region from="146" to="165" loc="I"/>
      <Region from="166" to="186" loc="M"/>
      <Region from="187" to="200" loc="O"/>
      <Region from="201" to="215" loc="M"/>
      <Region from="216" to="216" loc="I"/>
      <Region from="217" to="231" loc="M"/>
      <Region from="232" to="258" loc="O"/>
      <Region from="259" to="279" loc="M"/>
      <Region from="280" to="757" loc="I"/>
    </Prediction>
    <Prediction name="Philius">
      <Region from="1" to="203" loc="I"/>
      <Region from="204" to="229" loc="M"/>
      <Region from="230" to="757" loc="O"/>
    </Prediction>
    <Prediction name="Phobius">
      <Region from="1" to="203" loc="I"/>
      <Region from="204" to="229" loc="M"/>
      <Region from="230" to="259" loc="O"/>
      <Region from="260" to="278" loc="M"/>
      <Region from="279" to="757" loc="I"/>
    </Prediction>
    <Prediction name="Pro">
      <Region from="1" to="93" loc="I"/>
      <Region from="94" to="114" loc="M"/>
      <Region from="115" to="125" loc="O"/>
      <Region from="126" to="146" loc="M"/>
      <Region from="147" to="166" loc="I"/>
      <Region from="167" to="187" loc="M"/>
      <Region from="188" to="207" loc="O"/>
      <Region from="208" to="228" loc="M"/>
      <Region from="229" to="757" loc="I"/>
    </Prediction>
    <Prediction name="Prodiv">
      <Region from="1" to="96" loc="I"/>
      <Region from="97" to="117" loc="M"/>
      <Region from="118" to="132" loc="O"/>
      <Region from="133" to="152" loc="M"/>
      <Region from="153" to="206" loc="I"/>
      <Region from="207" to="227" loc="M"/>
      <Region from="228" to="257" loc="O"/>
      <Region from="258" to="278" loc="M"/>
      <Region from="279" to="757" loc="I"/>
    </Prediction>
    <Prediction name="Scampi2">
      <Region from="1" to="208" loc="O"/>
      <Region from="209" to="228" loc="M"/>
      <Region from="229" to="757" loc="I"/>
    </Prediction>
    <Prediction name="ScampiMsa2">
      <Region from="1" to="208" loc="O"/>
      <Region from="209" to="229" loc="M"/>
      <Region from="230" to="757" loc="I"/>
    </Prediction>
    <Prediction name="SignalP">
      <Region/>
    </Prediction>
    <Prediction name="TMHMM">
      <Region/>
    </Prediction>
  </Predictions>
  <Constraints>
    <Constraint source="TOPDB" sourceId="7mbt_A">
      <ConstraintRegion from="16" to="429" loc="I" subId="17186394" subSource="7mbt_A"/>
      <ConstraintRegion from="446" to="473" loc="I" subId="17186396" subSource="7mbt_A"/>
      <ConstraintRegion from="489" to="653" loc="I" subId="17186398" subSource="7mbt_A"/>
      <ConstraintRegion from="698" to="720" loc="I" subId="17186400" subSource="7mbt_A"/>
      <ConstraintRegion from="721" to="738" loc="H" subId="17186401" subSource="7mbt_A"/>
      <ConstraintRegion from="739" to="752" loc="O" subId="17186402" subSource="7mbt_A"/>
      <ConstraintRegion from="753" to="770" loc="H" subId="17186403" subSource="7mbt_A"/>
      <ConstraintRegion from="771" to="792" loc="I" subId="17186404" subSource="7mbt_A"/>
      <ConstraintRegion from="793" to="810" loc="H" subId="17186405" subSource="7mbt_A"/>
      <ConstraintRegion from="811" to="820" loc="O" subId="17186406" subSource="7mbt_A"/>
      <ConstraintRegion from="821" to="839" loc="H" subId="17186407" subSource="7mbt_A"/>
      <ConstraintRegion from="840" to="858" loc="I" subId="17186408" subSource="7mbt_A"/>
      <ConstraintRegion from="859" to="880" loc="H" subId="17186409" subSource="7mbt_A"/>
      <ConstraintRegion from="881" to="892" loc="O" subId="17186410" subSource="7mbt_A"/>
      <ConstraintRegion from="893" to="907" loc="L" subId="17186411" subSource="7mbt_A"/>
      <ConstraintRegion from="908" to="944" loc="O" subId="17186412" subSource="7mbt_A"/>
      <ConstraintRegion from="945" to="966" loc="H" subId="17186413" subSource="7mbt_A"/>
      <ConstraintRegion from="967" to="1020" loc="I" subId="17186415" subSource="7mbt_A"/>
      <ConstraintRegion from="1027" to="1092" loc="I" subId="17186419" subSource="7mbt_A"/>
      <ConstraintRegion from="16" to="429" loc="I" subId="17186427" subSource="7mbt_B"/>
      <ConstraintRegion from="446" to="473" loc="I" subId="17186431" subSource="7mbt_B"/>
      <ConstraintRegion from="489" to="653" loc="I" subId="17186435" subSource="7mbt_B"/>
      <ConstraintRegion from="698" to="720" loc="I" subId="17186439" subSource="7mbt_B"/>
      <ConstraintRegion from="721" to="738" loc="H" subId="17186441" subSource="7mbt_B"/>
      <ConstraintRegion from="739" to="752" loc="O" subId="17186443" subSource="7mbt_B"/>
      <ConstraintRegion from="753" to="770" loc="H" subId="17186445" subSource="7mbt_B"/>
      <ConstraintRegion from="771" to="792" loc="I" subId="17186447" subSource="7mbt_B"/>
      <ConstraintRegion from="793" to="810" loc="H" subId="17186449" subSource="7mbt_B"/>
      <ConstraintRegion from="811" to="820" loc="O" subId="17186450" subSource="7mbt_B"/>
      <ConstraintRegion from="821" to="839" loc="H" subId="17186451" subSource="7mbt_B"/>
      <ConstraintRegion from="840" to="858" loc="I" subId="17186452" subSource="7mbt_B"/>
      <ConstraintRegion from="859" to="880" loc="H" subId="17186454" subSource="7mbt_B"/>
      <ConstraintRegion from="881" to="892" loc="O" subId="17186456" subSource="7mbt_B"/>
      <ConstraintRegion from="893" to="907" loc="L" subId="17186458" subSource="7mbt_B"/>
      <ConstraintRegion from="908" to="944" loc="O" subId="17186460" subSource="7mbt_B"/>
      <ConstraintRegion from="945" to="966" loc="H" subId="17186462" subSource="7mbt_B"/>
      <ConstraintRegion from="967" to="1020" loc="I" subId="17186464" subSource="7mbt_B"/>
      <ConstraintRegion from="1027" to="1092" loc="I" subId="17186468" subSource="7mbt_B"/>
      <ConstraintRegion from="16" to="429" loc="I" subId="17186476" subSource="7mbt_C"/>
      <ConstraintRegion from="446" to="473" loc="I" subId="17186480" subSource="7mbt_C"/>
      <ConstraintRegion from="489" to="653" loc="I" subId="17186484" subSource="7mbt_C"/>
      <ConstraintRegion from="698" to="720" loc="I" subId="17186488" subSource="7mbt_C"/>
      <ConstraintRegion from="721" to="738" loc="H" subId="17186489" subSource="7mbt_C"/>
      <ConstraintRegion from="739" to="752" loc="O" subId="17186490" subSource="7mbt_C"/>
      <ConstraintRegion from="753" to="770" loc="H" subId="17186491" subSource="7mbt_C"/>
      <ConstraintRegion from="771" to="792" loc="I" subId="17186492" subSource="7mbt_C"/>
      <ConstraintRegion from="793" to="810" loc="H" subId="17186494" subSource="7mbt_C"/>
      <ConstraintRegion from="811" to="820" loc="O" subId="17186496" subSource="7mbt_C"/>
      <ConstraintRegion from="821" to="839" loc="H" subId="17186498" subSource="7mbt_C"/>
      <ConstraintRegion from="840" to="858" loc="I" subId="17186500" subSource="7mbt_C"/>
      <ConstraintRegion from="859" to="880" loc="H" subId="17186502" subSource="7mbt_C"/>
      <ConstraintRegion from="881" to="892" loc="O" subId="17186504" subSource="7mbt_C"/>
      <ConstraintRegion from="893" to="907" loc="L" subId="17186506" subSource="7mbt_C"/>
      <ConstraintRegion from="908" to="944" loc="O" subId="17186508" subSource="7mbt_C"/>
      <ConstraintRegion from="945" to="966" loc="H" subId="17186510" subSource="7mbt_C"/>
      <ConstraintRegion from="967" to="1020" loc="I" subId="17186512" subSource="7mbt_C"/>
      <ConstraintRegion from="1027" to="1092" loc="I" subId="17186516" subSource="7mbt_C"/>
      <ConstraintRegion from="16" to="429" loc="I" subId="17186524" subSource="7mbt_D"/>
      <ConstraintRegion from="446" to="473" loc="I" subId="17186528" subSource="7mbt_D"/>
      <ConstraintRegion from="489" to="653" loc="I" subId="17186530" subSource="7mbt_D"/>
      <ConstraintRegion from="698" to="720" loc="I" subId="17186532" subSource="7mbt_D"/>
      <ConstraintRegion from="721" to="738" loc="H" subId="17186533" subSource="7mbt_D"/>
      <ConstraintRegion from="739" to="752" loc="O" subId="17186534" subSource="7mbt_D"/>
      <ConstraintRegion from="753" to="770" loc="H" subId="17186535" subSource="7mbt_D"/>
      <ConstraintRegion from="771" to="792" loc="I" subId="17186536" subSource="7mbt_D"/>
      <ConstraintRegion from="793" to="810" loc="H" subId="17186537" subSource="7mbt_D"/>
      <ConstraintRegion from="811" to="820" loc="O" subId="17186538" subSource="7mbt_D"/>
      <ConstraintRegion from="821" to="839" loc="H" subId="17186539" subSource="7mbt_D"/>
      <ConstraintRegion from="840" to="858" loc="I" subId="17186541" subSource="7mbt_D"/>
      <ConstraintRegion from="859" to="880" loc="H" subId="17186543" subSource="7mbt_D"/>
      <ConstraintRegion from="881" to="892" loc="O" subId="17186545" subSource="7mbt_D"/>
      <ConstraintRegion from="893" to="907" loc="L" subId="17186547" subSource="7mbt_D"/>
      <ConstraintRegion from="908" to="944" loc="O" subId="17186549" subSource="7mbt_D"/>
      <ConstraintRegion from="945" to="966" loc="H" subId="17186551" subSource="7mbt_D"/>
      <ConstraintRegion from="967" to="1020" loc="I" subId="17186553" subSource="7mbt_D"/>
      <ConstraintRegion from="1027" to="1092" loc="I" subId="17186557" subSource="7mbt_D"/>
      <ConstraintRegion from="16" to="429" loc="I" subId="17186593" subSource="7mbu_A"/>
      <ConstraintRegion from="446" to="473" loc="I" subId="17186596" subSource="7mbu_A"/>
      <ConstraintRegion from="489" to="653" loc="I" subId="17186599" subSource="7mbu_A"/>
      <ConstraintRegion from="698" to="698" loc="I" subId="17186602" subSource="7mbu_A"/>
      <ConstraintRegion from="699" to="713" loc="F" subId="17186605" subSource="7mbu_A"/>
      <ConstraintRegion from="714" to="719" loc="I" subId="17186608" subSource="7mbu_A"/>
      <ConstraintRegion from="720" to="739" loc="H" subId="17186610" subSource="7mbu_A"/>
      <ConstraintRegion from="740" to="752" loc="O" subId="17186612" subSource="7mbu_A"/>
      <ConstraintRegion from="753" to="770" loc="H" subId="17186615" subSource="7mbu_A"/>
      <ConstraintRegion from="771" to="780" loc="I" subId="17186618" subSource="7mbu_A"/>
      <ConstraintRegion from="781" to="790" loc="F" subId="17186621" subSource="7mbu_A"/>
      <ConstraintRegion from="791" to="792" loc="I" subId="17186624" subSource="7mbu_A"/>
      <ConstraintRegion from="793" to="810" loc="H" subId="17186627" subSource="7mbu_A"/>
      <ConstraintRegion from="811" to="820" loc="O" subId="17186629" subSource="7mbu_A"/>
      <ConstraintRegion from="821" to="839" loc="H" subId="17186631" subSource="7mbu_A"/>
      <ConstraintRegion from="840" to="842" loc="I" subId="17186633" subSource="7mbu_A"/>
      <ConstraintRegion from="843" to="855" loc="F" subId="17186636" subSource="7mbu_A"/>
      <ConstraintRegion from="856" to="880" loc="H" subId="17186639" subSource="7mbu_A"/>
      <ConstraintRegion from="881" to="892" loc="O" subId="17186642" subSource="7mbu_A"/>
      <ConstraintRegion from="893" to="907" loc="L" subId="17186644" subSource="7mbu_A"/>
      <ConstraintRegion from="908" to="944" loc="O" subId="17186646" subSource="7mbu_A"/>
      <ConstraintRegion from="945" to="966" loc="H" subId="17186649" subSource="7mbu_A"/>
      <ConstraintRegion from="967" to="997" loc="F" subId="17186651" subSource="7mbu_A"/>
      <ConstraintRegion from="998" to="1020" loc="I" subId="17186653" subSource="7mbu_A"/>
      <ConstraintRegion from="1027" to="1092" loc="I" subId="17186655" subSource="7mbu_A"/>
      <ConstraintRegion from="16" to="429" loc="I" subId="17186659" subSource="7mbu_B"/>
      <ConstraintRegion from="446" to="473" loc="I" subId="17186661" subSource="7mbu_B"/>
      <ConstraintRegion from="489" to="653" loc="I" subId="17186663" subSource="7mbu_B"/>
      <ConstraintRegion from="698" to="698" loc="I" subId="17186665" subSource="7mbu_B"/>
      <ConstraintRegion from="699" to="713" loc="F" subId="17186667" subSource="7mbu_B"/>
      <ConstraintRegion from="714" to="719" loc="I" subId="17186669" subSource="7mbu_B"/>
      <ConstraintRegion from="720" to="739" loc="H" subId="17186671" subSource="7mbu_B"/>
      <ConstraintRegion from="740" to="752" loc="O" subId="17186672" subSource="7mbu_B"/>
      <ConstraintRegion from="753" to="770" loc="H" subId="17186673" subSource="7mbu_B"/>
      <ConstraintRegion from="771" to="780" loc="I" subId="17186674" subSource="7mbu_B"/>
      <ConstraintRegion from="781" to="790" loc="F" subId="17186675" subSource="7mbu_B"/>
      <ConstraintRegion from="791" to="792" loc="I" subId="17186676" subSource="7mbu_B"/>
      <ConstraintRegion from="793" to="810" loc="H" subId="17186677" subSource="7mbu_B"/>
      <ConstraintRegion from="811" to="820" loc="O" subId="17186678" subSource="7mbu_B"/>
      <ConstraintRegion from="821" to="839" loc="H" subId="17186679" subSource="7mbu_B"/>
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      <ConstraintRegion from="731" to="753" loc="I" subId="17087905" subSource="6g1k_B"/>
      <ConstraintRegion from="18" to="118" loc="I" subId="17087908" subSource="6g1k_C"/>
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      <ConstraintRegion from="187" to="272" loc="I" subId="17087912" subSource="6g1k_C"/>
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      <ConstraintRegion from="538" to="564" loc="O" subId="17087928" subSource="6g1k_C"/>
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      <ConstraintRegion from="618" to="648" loc="I" subId="17087932" subSource="6g1k_C"/>
      <ConstraintRegion from="652" to="656" loc="I" subId="17087934" subSource="6g1k_C"/>
      <ConstraintRegion from="660" to="658" loc="I" subId="17087936" subSource="6g1k_C"/>
      <ConstraintRegion from="696" to="727" loc="I" subId="17087937" subSource="6g1k_C"/>
      <ConstraintRegion from="731" to="753" loc="I" subId="17087939" subSource="6g1k_C"/>
      <ConstraintRegion from="18" to="118" loc="I" subId="17087942" subSource="6g1k_D"/>
      <ConstraintRegion from="135" to="172" loc="I" subId="17087944" subSource="6g1k_D"/>
      <ConstraintRegion from="187" to="272" loc="I" subId="17087946" subSource="6g1k_D"/>
      <ConstraintRegion from="284" to="319" loc="I" subId="17087948" subSource="6g1k_D"/>
      <ConstraintRegion from="324" to="367" loc="I" subId="17087950" subSource="6g1k_D"/>
      <ConstraintRegion from="368" to="384" loc="H" subId="17087951" subSource="6g1k_D"/>
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      <ConstraintRegion from="434" to="453" loc="H" subId="17087957" subSource="6g1k_D"/>
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    </Constraint>
    <Constraint source="TOPDB" sourceId="6pw5_A">
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      <ConstraintRegion from="324" to="511" loc="I" subId="17255646" subSource="6pw5_A"/>
      <ConstraintRegion from="512" to="524" loc="H" subId="17255649" subSource="6pw5_A"/>
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      <ConstraintRegion from="546" to="574" loc="I" subId="17255658" subSource="6pw5_A"/>
      <ConstraintRegion from="575" to="593" loc="H" subId="17255662" subSource="6pw5_A"/>
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      <ConstraintRegion from="647" to="663" loc="H" subId="17255675" subSource="6pw5_A"/>
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      <ConstraintRegion from="737" to="874" loc="I" subId="17255683" subSource="6pw5_A"/>
      <ConstraintRegion from="17" to="33" loc="I" subId="17255755" subSource="6pw5_C"/>
      <ConstraintRegion from="53" to="246" loc="I" subId="17255757" subSource="6pw5_C"/>
      <ConstraintRegion from="324" to="504" loc="I" subId="17255760" subSource="6pw5_C"/>
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      <ConstraintRegion from="570" to="584" loc="H" subId="17255771" subSource="6pw5_C"/>
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    </Constraint>
    <Constraint source="TOPDB" sourceId="6pw5_B">
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      <ConstraintRegion from="461" to="464" loc="I" subId="17255700" subSource="6pw5_B"/>
      <ConstraintRegion from="465" to="474" loc="F" subId="17255704" subSource="6pw5_B"/>
      <ConstraintRegion from="475" to="508" loc="I" subId="17255708" subSource="6pw5_B"/>
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      <ConstraintRegion from="640" to="645" loc="I" subId="17255733" subSource="6pw5_B"/>
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      <ConstraintRegion from="17" to="280" loc="I" subId="17255809" subSource="6pw5_D"/>
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      <ConstraintRegion from="777" to="796" loc="F" subId="17255862" subSource="6pw5_D"/>
      <ConstraintRegion from="797" to="872" loc="I" subId="17255864" subSource="6pw5_D"/>
    </Constraint>
  </Constraints>
</HtpItem>
