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    <TOPDB id="SC6A4_HUMAN">
      <Alignment>
        <CrossRefSeq>VPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNIT-----------------WTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAK-RRERFVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCRDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPYWSIILGYCIGTSSFICIPTYIAYRLIITPGTFKE</CrossRefSeq>
        <OrigSeq>MVGKGAKGMLNGAVPSEAT---KRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKL--SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADH-GPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGEHSSLRPPATRPLARPLCPAGLLTPHLSRAPELLPGH-PDDAGIPTTPLLSDLLALRLSRHHLPPGSGPPPPPPE-SSSLRVAPGAERA</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="SC6A4_RAT">
      <Alignment>
        <CrossRefSeq>VPSTSAGDEASHSIPAATTTLVAEIRQGERETWGKKMDFLLSVIGYAVDLGNIWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIIAWALYYLISSLTDRLPWTSCTNSWNTGNCTNYFAQDNIT-----------------WTLHSTSPAEEFYLRHVLQIHQSKGLQDLGTISWQLTLCIVLIFTVIYFSIWKGVKTSGKVVWVTATFPYIVLSVLLVRGATLPGAWRGVVFYLKPNWQKLLETGVWVDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHIWAKRREW-FVLIVVITCVLGSLLTLTSGGAYVVTLLEEYATGPAVLTVALIEAVAVSWFYGITQFCSDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPHWSIVLGYCIGMSSVICIPTYIIYRLISTPGTLKE</CrossRefSeq>
        <OrigSeq>MVGKGAKGMLNGAVPSEAT---KRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKL--SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADH-GPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGEHSSLRPPATRPLARPLCPAGLLTPHLSRAPELLPGH-PDDAGIPTTPLLSDLLALRLSRHHLPPGSGPPPPPPE-SSSLRVAPGAERA</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="DAT_DROME">
      <Alignment>
        <CrossRefSeq>MSPTGHISKSKTPTPHDNDNNSISDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPK--IKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLL--FITVYGLIGYEPLTYAD-YVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQ</CrossRefSeq>
        <OrigSeq>MVGKGAKGMLNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGV-------------------LDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKL--SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGEHSSLRPPATRPLARPLCPAGLLTPHLSRAPELLPGHPDDAGIPTTPLLSDLLALRLSR----HHLPPGSGPPPPPPES-SSLRVAPGAERA</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="SC6A1_MOUSE">
      <Alignment>
        <CrossRefSeq>ASDKPKTLVVKVQKKAGDLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSLVNTTN--------------------MTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPR-LLRNRRELFIAAVCIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTP--IIVAGVFLFSAVQMTPLTMGS-YVFPKWGQGVGWLMALSSMVLIPGYMAYMFLT</CrossRefSeq>
        <OrigSeq>AKGMLNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGEHSSLRPPATRPLARPLCPAGLLTPHLSRAPELLPGHPDDAGIPTTPLLSDLLALRLSR----HHLPPGSGPPPPPPESSSLRVA</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="INE_DROME">
      <Alignment>
        <CrossRefSeq>DDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCW----------------VPQRKGINASAPDTSRTPSEEFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPC--LLFAIWVLSLINYHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAV</CrossRefSeq>
        <OrigSeq>GMLNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVG--NEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGEHSSLRPPATRPLARPLCPAGLLTPHLSRAPELLPGHPDDAGIPTTPLLS-DLLALRLSR----HHLPPGSGPPPPPPESS</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="SC6A6_HUMAN">
      <Alignment>
        <CrossRefSeq>KPSPGKSPGTRPED-EAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKS------------VWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITP--VLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLCQTEGPF</CrossRefSeq>
        <OrigSeq>KGAKGMLNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQ-KKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGEHSSLRPPATRPLARPLCPAGLLTPHLSRAPELLPGHPDDAGIPTTPLLSDLLALRLSR----HHLPPGSGPPPPPPES-SSLRVAPGAE</OrigSeq>
      </Alignment>
    </TOPDB>
    <TOPDB id="NAAT1_DROME">
      <Alignment>
        <CrossRefSeq>TNAASTEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIWSVVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSELPWSYCRDEWTNCVNSRPQEYVDNLLTGVSLANESARNLSGIVANDETEKLQSSSELYFLNVVIKEKLDISDGVGDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKG----WKYWKVALTTSVCGFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSFFTPVMMII--IFIYSMVTIEPIKYSELYFPEAANIAGWLLFAIGAAQFPLWGLWYISRHPQGTYWKSLKASLKPSDRWGPANPEIRR</CrossRefSeq>
        <OrigSeq>LNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASN----LTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGN-FGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGV-DVSRVADHGPGLAFVAYPEALTLLPISP-LWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGEHSSLRPPATRPLARPLCPAGLLTPHLSRAPELLPGHPDDAGIPTTPLLSDLLA------------------LRLSRHHLPPGSGPPPPPPESSSLRVAPGAERAPPPAPTAR</OrigSeq>
      </Alignment>
    </TOPDB>
  </CrossRef>
  <Sequence Length="579" CheckSum="9b930d5501fcc618576e24d971d3ef0a">
    <Seq>
      MVGKGAKGML NGAVPSEATK RDQNLKRGNW GNQIEFVLTS VGYAVGLGNV
      WRFPYLCYRN GGGAFMFPYF IMLIFCGIPL FFMELSFGQF ASQGCLGVWR
      ISPMFKGVGY GMMVVSTYIG IYYNVVICIA FYYFFSSMTH VLPWAYCNNP
      WNTHDCAGVL DASNLTNGSR PAALPSNLSH LLNHSLQRTS PSEEYWRLYV
      LKLSDDIGNF GEVRLPLLGC LGVSWLVVFL CLIRGVKSSG KVVYFTATFP
      YVVLTILFVR GVTLEGAFDG IMYYLTPQWD KILEAKVWGD AASQIFYSLG
      CAWGGLITMA SYNKFHNNCY RDSVIISITN CATSVYAGFV IFSILGFMAN
      HLGVDVSRVA DHGPGLAFVA YPEALTLLPI SPLWSLLFFF MLILLGLGTQ
      FCLLETLVTA IVDEVGNEWI LQKKTYVTLG VAVAGFLLGI PLTSQAGIYW
      LLLMDNYAAS FSLVVISCIM CVAIMYIYGE HSSLRPPATR PLARPLCPAG
      LLTPHLSRAP ELLPGHPDDA GIPTTPLLSD LLALRLSRHH LPPGSGPPPP
      PPESSSLRVA PGAERAPPPA PTARGSAGA
    </Seq>
  </Sequence>
  <Topology numTm="12" reliability="91.93">
    <Region from="1" to="35" loc="I"/>
    <Region from="36" to="53" loc="M"/>
    <Region from="54" to="63" loc="O"/>
    <Region from="64" to="82" loc="M"/>
    <Region from="83" to="106" loc="I"/>
    <Region from="107" to="131" loc="M"/>
    <Region from="132" to="214" loc="O"/>
    <Region from="215" to="233" loc="M"/>
    <Region from="234" to="239" loc="I"/>
    <Region from="240" to="259" loc="M"/>
    <Region from="260" to="281" loc="O"/>
    <Region from="282" to="306" loc="M"/>
    <Region from="307" to="322" loc="I"/>
    <Region from="323" to="340" loc="M"/>
    <Region from="341" to="382" loc="O"/>
    <Region from="383" to="408" loc="M"/>
    <Region from="409" to="424" loc="I"/>
    <Region from="425" to="443" loc="M"/>
    <Region from="444" to="449" loc="O"/>
    <Region from="450" to="472" loc="M"/>
    <Region from="473" to="500" loc="I"/>
    <Region from="501" to="523" loc="M"/>
    <Region from="524" to="538" loc="O"/>
    <Region from="539" to="554" loc="M"/>
    <Region from="555" to="579" loc="I"/>
  </Topology>
  <Predictions>
    <Prediction name="Hmmtop">
      <Region from="1" to="33" loc="I"/>
      <Region from="34" to="47" loc="M"/>
      <Region from="48" to="63" loc="O"/>
      <Region from="64" to="83" loc="M"/>
      <Region from="84" to="106" loc="I"/>
      <Region from="107" to="131" loc="M"/>
      <Region from="132" to="214" loc="O"/>
      <Region from="215" to="233" loc="M"/>
      <Region from="234" to="242" loc="I"/>
      <Region from="243" to="264" loc="M"/>
      <Region from="265" to="294" loc="O"/>
      <Region from="295" to="310" loc="M"/>
      <Region from="311" to="323" loc="I"/>
      <Region from="324" to="345" loc="M"/>
      <Region from="346" to="373" loc="O"/>
      <Region from="374" to="399" loc="M"/>
      <Region from="400" to="424" loc="I"/>
      <Region from="425" to="444" loc="M"/>
      <Region from="445" to="457" loc="O"/>
      <Region from="458" to="477" loc="M"/>
      <Region from="478" to="504" loc="I"/>
      <Region from="505" to="522" loc="M"/>
      <Region from="523" to="538" loc="O"/>
      <Region from="539" to="555" loc="M"/>
      <Region from="556" to="579" loc="I"/>
    </Prediction>
    <Prediction name="Memsat">
      <Region from="1" to="34" loc="I"/>
      <Region from="35" to="54" loc="M"/>
      <Region from="55" to="62" loc="O"/>
      <Region from="63" to="85" loc="M"/>
      <Region from="86" to="106" loc="I"/>
      <Region from="107" to="137" loc="M"/>
      <Region from="138" to="215" loc="O"/>
      <Region from="216" to="233" loc="M"/>
      <Region from="234" to="240" loc="I"/>
      <Region from="241" to="263" loc="M"/>
      <Region from="264" to="287" loc="O"/>
      <Region from="288" to="309" loc="M"/>
      <Region from="310" to="322" loc="I"/>
      <Region from="323" to="348" loc="M"/>
      <Region from="349" to="382" loc="O"/>
      <Region from="383" to="412" loc="M"/>
      <Region from="413" to="425" loc="I"/>
      <Region from="426" to="444" loc="M"/>
      <Region from="445" to="447" loc="O"/>
      <Region from="448" to="477" loc="M"/>
      <Region from="478" to="492" loc="I"/>
      <Region from="493" to="508" loc="M"/>
      <Region from="509" to="579" loc="O"/>
    </Prediction>
    <Prediction name="Octopus">
      <Region from="1" to="30" loc="I"/>
      <Region from="31" to="51" loc="M"/>
      <Region from="52" to="55" loc="O"/>
      <Region from="56" to="58" loc="L"/>
      <Region from="59" to="62" loc="O"/>
      <Region from="63" to="83" loc="M"/>
      <Region from="84" to="103" loc="I"/>
      <Region from="104" to="134" loc="M"/>
      <Region from="135" to="212" loc="O"/>
      <Region from="213" to="233" loc="M"/>
      <Region from="234" to="242" loc="I"/>
      <Region from="243" to="257" loc="M"/>
      <Region from="258" to="258" loc="O"/>
      <Region from="259" to="273" loc="M"/>
      <Region from="274" to="287" loc="I"/>
      <Region from="288" to="308" loc="M"/>
      <Region from="309" to="324" loc="O"/>
      <Region from="325" to="345" loc="M"/>
      <Region from="346" to="358" loc="I"/>
      <Region from="359" to="379" loc="M"/>
      <Region from="380" to="380" loc="O"/>
      <Region from="381" to="411" loc="M"/>
      <Region from="412" to="426" loc="I"/>
      <Region from="427" to="447" loc="M"/>
      <Region from="448" to="457" loc="O"/>
      <Region from="458" to="478" loc="M"/>
      <Region from="479" to="490" loc="I"/>
      <Region from="491" to="511" loc="M"/>
      <Region from="512" to="557" loc="O"/>
      <Region from="558" to="578" loc="M"/>
      <Region from="579" to="579" loc="I"/>
    </Prediction>
    <Prediction name="Philius">
      <Region from="1" to="33" loc="I"/>
      <Region from="34" to="53" loc="M"/>
      <Region from="54" to="64" loc="O"/>
      <Region from="65" to="88" loc="M"/>
      <Region from="89" to="108" loc="I"/>
      <Region from="109" to="135" loc="M"/>
      <Region from="136" to="212" loc="O"/>
      <Region from="213" to="233" loc="M"/>
      <Region from="234" to="241" loc="I"/>
      <Region from="242" to="264" loc="M"/>
      <Region from="265" to="294" loc="O"/>
      <Region from="295" to="313" loc="M"/>
      <Region from="314" to="323" loc="I"/>
      <Region from="324" to="347" loc="M"/>
      <Region from="348" to="382" loc="O"/>
      <Region from="383" to="404" loc="M"/>
      <Region from="405" to="424" loc="I"/>
      <Region from="425" to="449" loc="M"/>
      <Region from="450" to="456" loc="O"/>
      <Region from="457" to="479" loc="M"/>
      <Region from="480" to="579" loc="I"/>
    </Prediction>
    <Prediction name="Phobius">
      <Region from="1" to="35" loc="I"/>
      <Region from="36" to="54" loc="M"/>
      <Region from="55" to="65" loc="O"/>
      <Region from="66" to="87" loc="M"/>
      <Region from="88" to="107" loc="I"/>
      <Region from="108" to="135" loc="M"/>
      <Region from="136" to="214" loc="O"/>
      <Region from="215" to="236" loc="M"/>
      <Region from="237" to="247" loc="I"/>
      <Region from="248" to="275" loc="M"/>
      <Region from="276" to="294" loc="O"/>
      <Region from="295" to="312" loc="M"/>
      <Region from="313" to="323" loc="I"/>
      <Region from="324" to="349" loc="M"/>
      <Region from="350" to="382" loc="O"/>
      <Region from="383" to="404" loc="M"/>
      <Region from="405" to="424" loc="I"/>
      <Region from="425" to="451" loc="M"/>
      <Region from="452" to="456" loc="O"/>
      <Region from="457" to="478" loc="M"/>
      <Region from="479" to="579" loc="I"/>
    </Prediction>
    <Prediction name="Pro">
      <Region from="1" to="36" loc="I"/>
      <Region from="37" to="57" loc="M"/>
      <Region from="58" to="62" loc="O"/>
      <Region from="63" to="83" loc="M"/>
      <Region from="84" to="103" loc="I"/>
      <Region from="104" to="124" loc="M"/>
      <Region from="125" to="209" loc="O"/>
      <Region from="210" to="230" loc="M"/>
      <Region from="231" to="250" loc="I"/>
      <Region from="251" to="271" loc="M"/>
      <Region from="272" to="291" loc="O"/>
      <Region from="292" to="312" loc="M"/>
      <Region from="313" to="323" loc="I"/>
      <Region from="324" to="344" loc="M"/>
      <Region from="345" to="382" loc="O"/>
      <Region from="383" to="403" loc="M"/>
      <Region from="404" to="423" loc="I"/>
      <Region from="424" to="444" loc="M"/>
      <Region from="445" to="459" loc="O"/>
      <Region from="460" to="480" loc="M"/>
      <Region from="481" to="500" loc="I"/>
      <Region from="501" to="521" loc="M"/>
      <Region from="522" to="579" loc="O"/>
    </Prediction>
    <Prediction name="Prodiv">
      <Region from="1" to="35" loc="I"/>
      <Region from="36" to="56" loc="M"/>
      <Region from="57" to="66" loc="O"/>
      <Region from="67" to="87" loc="M"/>
      <Region from="88" to="107" loc="I"/>
      <Region from="108" to="128" loc="M"/>
      <Region from="129" to="212" loc="O"/>
      <Region from="213" to="233" loc="M"/>
      <Region from="234" to="244" loc="I"/>
      <Region from="245" to="265" loc="M"/>
      <Region from="266" to="291" loc="O"/>
      <Region from="292" to="312" loc="M"/>
      <Region from="313" to="323" loc="I"/>
      <Region from="324" to="344" loc="M"/>
      <Region from="345" to="376" loc="O"/>
      <Region from="377" to="397" loc="M"/>
      <Region from="398" to="426" loc="I"/>
      <Region from="427" to="447" loc="M"/>
      <Region from="448" to="457" loc="O"/>
      <Region from="458" to="478" loc="M"/>
      <Region from="479" to="504" loc="I"/>
      <Region from="505" to="525" loc="M"/>
      <Region from="526" to="579" loc="O"/>
    </Prediction>
    <Prediction name="Scampi2">
      <Region from="1" to="62" loc="I"/>
      <Region from="63" to="83" loc="M"/>
      <Region from="84" to="114" loc="O"/>
      <Region from="115" to="134" loc="M"/>
      <Region from="135" to="213" loc="I"/>
      <Region from="214" to="233" loc="M"/>
      <Region from="234" to="243" loc="O"/>
      <Region from="244" to="263" loc="M"/>
      <Region from="264" to="294" loc="I"/>
      <Region from="295" to="314" loc="M"/>
      <Region from="315" to="328" loc="O"/>
      <Region from="329" to="348" loc="M"/>
      <Region from="349" to="369" loc="I"/>
      <Region from="370" to="389" loc="M"/>
      <Region from="390" to="391" loc="O"/>
      <Region from="392" to="411" loc="M"/>
      <Region from="412" to="424" loc="I"/>
      <Region from="425" to="444" loc="M"/>
      <Region from="445" to="457" loc="O"/>
      <Region from="458" to="478" loc="M"/>
      <Region from="479" to="579" loc="I"/>
    </Prediction>
    <Prediction name="ScampiMsa2">
      <Region from="1" to="64" loc="O"/>
      <Region from="65" to="85" loc="M"/>
      <Region from="86" to="106" loc="I"/>
      <Region from="107" to="127" loc="M"/>
      <Region from="128" to="212" loc="O"/>
      <Region from="213" to="233" loc="M"/>
      <Region from="234" to="243" loc="I"/>
      <Region from="244" to="264" loc="M"/>
      <Region from="265" to="291" loc="O"/>
      <Region from="292" to="312" loc="M"/>
      <Region from="313" to="328" loc="I"/>
      <Region from="329" to="349" loc="M"/>
      <Region from="350" to="381" loc="O"/>
      <Region from="382" to="402" loc="M"/>
      <Region from="403" to="425" loc="I"/>
      <Region from="426" to="446" loc="M"/>
      <Region from="447" to="457" loc="O"/>
      <Region from="458" to="478" loc="M"/>
      <Region from="479" to="579" loc="I"/>
    </Prediction>
    <Prediction name="SignalP">
      <Region/>
    </Prediction>
    <Prediction name="TMHMM">
      <Region from="1" to="28" loc="I"/>
      <Region from="29" to="51" loc="M"/>
      <Region from="52" to="60" loc="O"/>
      <Region from="61" to="83" loc="M"/>
      <Region from="84" to="113" loc="I"/>
      <Region from="114" to="136" loc="M"/>
      <Region from="137" to="212" loc="O"/>
      <Region from="213" to="235" loc="M"/>
      <Region from="236" to="241" loc="I"/>
      <Region from="242" to="264" loc="M"/>
      <Region from="265" to="290" loc="O"/>
      <Region from="291" to="313" loc="M"/>
      <Region from="314" to="325" loc="I"/>
      <Region from="326" to="348" loc="M"/>
      <Region from="349" to="381" loc="O"/>
      <Region from="382" to="404" loc="M"/>
      <Region from="405" to="424" loc="I"/>
      <Region from="425" to="447" loc="M"/>
      <Region from="448" to="456" loc="O"/>
      <Region from="457" to="479" loc="M"/>
      <Region from="480" to="579" loc="I"/>
    </Prediction>
  </Predictions>
  <Constraints>
    <Constraint source="TOPDB" sourceId="8de3_A">
      <ConstraintRegion from="116" to="123" loc="I" subId="17028566" subSource="8de3_A"/>
      <ConstraintRegion from="124" to="142" loc="H" subId="17028568" subSource="8de3_A"/>
      <ConstraintRegion from="143" to="154" loc="O" subId="17028570" subSource="8de3_A"/>
      <ConstraintRegion from="155" to="174" loc="H" subId="17028572" subSource="8de3_A"/>
      <ConstraintRegion from="175" to="197" loc="I" subId="17028574" subSource="8de3_A"/>
      <ConstraintRegion from="198" to="222" loc="H" subId="17028576" subSource="8de3_A"/>
      <ConstraintRegion from="223" to="288" loc="O" subId="17028578" subSource="8de3_A"/>
      <ConstraintRegion from="289" to="308" loc="H" subId="17028580" subSource="8de3_A"/>
      <ConstraintRegion from="309" to="313" loc="I" subId="17028582" subSource="8de3_A"/>
      <ConstraintRegion from="314" to="333" loc="H" subId="17028584" subSource="8de3_A"/>
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    </Constraint>
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    <Constraint source="TOPDB" sourceId="7dii_B">
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    </Constraint>
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    </Constraint>
    <Constraint source="TOPDB" sourceId="7dj2_A">
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    </Constraint>
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    </Constraint>
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    </Constraint>
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    </Constraint>
    <Constraint source="TOPDB" sourceId="7dj1_A">
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      <ConstraintRegion from="326" to="331" loc="F" subId="17033100" subSource="7dj1_A"/>
      <ConstraintRegion from="332" to="339" loc="O" subId="17033105" subSource="7dj1_A"/>
      <ConstraintRegion from="340" to="364" loc="H" subId="17033109" subSource="7dj1_A"/>
      <ConstraintRegion from="365" to="378" loc="I" subId="17033113" subSource="7dj1_A"/>
      <ConstraintRegion from="379" to="396" loc="H" subId="17033116" subSource="7dj1_A"/>
      <ConstraintRegion from="397" to="399" loc="O" subId="17033120" subSource="7dj1_A"/>
      <ConstraintRegion from="400" to="425" loc="H" subId="17033123" subSource="7dj1_A"/>
      <ConstraintRegion from="426" to="429" loc="I" subId="17033126" subSource="7dj1_A"/>
      <ConstraintRegion from="430" to="437" loc="F" subId="17033129" subSource="7dj1_A"/>
      <ConstraintRegion from="438" to="447" loc="I" subId="17033132" subSource="7dj1_A"/>
      <ConstraintRegion from="448" to="467" loc="H" subId="17033134" subSource="7dj1_A"/>
      <ConstraintRegion from="480" to="483" loc="O" subId="17033135" subSource="7dj1_A"/>
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      <ConstraintRegion from="502" to="507" loc="I" subId="17033137" subSource="7dj1_A"/>
    </Constraint>
    <Constraint source="TOPDB" sourceId="6yu2_A">
      <ConstraintRegion from="8" to="19" loc="I" subId="17447217" subSource="6yu2_A"/>
      <ConstraintRegion from="20" to="36" loc="H" subId="17447218" subSource="6yu2_A"/>
      <ConstraintRegion from="37" to="48" loc="O" subId="17447219" subSource="6yu2_A"/>
      <ConstraintRegion from="49" to="67" loc="H" subId="17447220" subSource="6yu2_A"/>
      <ConstraintRegion from="68" to="88" loc="I" subId="17447221" subSource="6yu2_A"/>
      <ConstraintRegion from="89" to="125" loc="H" subId="17447222" subSource="6yu2_A"/>
      <ConstraintRegion from="126" to="133" loc="O" subId="17447223" subSource="6yu2_A"/>
      <ConstraintRegion from="134" to="143" loc="F" subId="17447224" subSource="6yu2_A"/>
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      <ConstraintRegion from="166" to="175" loc="I" subId="17447227" subSource="6yu2_A"/>
      <ConstraintRegion from="176" to="193" loc="H" subId="17447228" subSource="6yu2_A"/>
      <ConstraintRegion from="194" to="199" loc="O" subId="17447229" subSource="6yu2_A"/>
      <ConstraintRegion from="200" to="208" loc="F" subId="17447230" subSource="6yu2_A"/>
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      <ConstraintRegion from="222" to="242" loc="H" subId="17447232" subSource="6yu2_A"/>
      <ConstraintRegion from="243" to="253" loc="I" subId="17447233" subSource="6yu2_A"/>
      <ConstraintRegion from="254" to="273" loc="H" subId="17447234" subSource="6yu2_A"/>
      <ConstraintRegion from="274" to="291" loc="O" subId="17447235" subSource="6yu2_A"/>
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      <ConstraintRegion from="334" to="347" loc="I" subId="17447239" subSource="6yu2_A"/>
      <ConstraintRegion from="348" to="363" loc="H" subId="17447240" subSource="6yu2_A"/>
      <ConstraintRegion from="364" to="383" loc="O" subId="17447241" subSource="6yu2_A"/>
      <ConstraintRegion from="384" to="407" loc="H" subId="17447242" subSource="6yu2_A"/>
      <ConstraintRegion from="408" to="409" loc="I" subId="17447243" subSource="6yu2_A"/>
      <ConstraintRegion from="410" to="416" loc="F" subId="17447244" subSource="6yu2_A"/>
      <ConstraintRegion from="417" to="423" loc="I" subId="17447245" subSource="6yu2_A"/>
      <ConstraintRegion from="424" to="445" loc="H" subId="17447246" subSource="6yu2_A"/>
      <ConstraintRegion from="446" to="448" loc="O" subId="17447247" subSource="6yu2_A"/>
      <ConstraintRegion from="8" to="19" loc="I" subId="17447248" subSource="6yu2_B"/>
      <ConstraintRegion from="20" to="36" loc="H" subId="17447249" subSource="6yu2_B"/>
      <ConstraintRegion from="37" to="48" loc="O" subId="17447250" subSource="6yu2_B"/>
      <ConstraintRegion from="49" to="67" loc="H" subId="17447251" subSource="6yu2_B"/>
      <ConstraintRegion from="68" to="88" loc="I" subId="17447252" subSource="6yu2_B"/>
      <ConstraintRegion from="89" to="125" loc="H" subId="17447253" subSource="6yu2_B"/>
      <ConstraintRegion from="126" to="133" loc="O" subId="17447254" subSource="6yu2_B"/>
      <ConstraintRegion from="134" to="144" loc="F" subId="17447255" subSource="6yu2_B"/>
      <ConstraintRegion from="145" to="147" loc="O" subId="17447256" subSource="6yu2_B"/>
      <ConstraintRegion from="148" to="165" loc="H" subId="17447257" subSource="6yu2_B"/>
      <ConstraintRegion from="166" to="175" loc="I" subId="17447258" subSource="6yu2_B"/>
      <ConstraintRegion from="176" to="193" loc="H" subId="17447259" subSource="6yu2_B"/>
      <ConstraintRegion from="194" to="199" loc="O" subId="17447260" subSource="6yu2_B"/>
      <ConstraintRegion from="200" to="208" loc="F" subId="17447261" subSource="6yu2_B"/>
      <ConstraintRegion from="209" to="221" loc="O" subId="17447262" subSource="6yu2_B"/>
      <ConstraintRegion from="222" to="242" loc="H" subId="17447263" subSource="6yu2_B"/>
      <ConstraintRegion from="243" to="253" loc="I" subId="17447264" subSource="6yu2_B"/>
      <ConstraintRegion from="254" to="273" loc="H" subId="17447265" subSource="6yu2_B"/>
      <ConstraintRegion from="274" to="290" loc="O" subId="17447266" subSource="6yu2_B"/>
      <ConstraintRegion from="291" to="302" loc="F" subId="17447267" subSource="6yu2_B"/>
      <ConstraintRegion from="303" to="305" loc="O" subId="17447268" subSource="6yu2_B"/>
      <ConstraintRegion from="306" to="333" loc="H" subId="17447269" subSource="6yu2_B"/>
      <ConstraintRegion from="334" to="347" loc="I" subId="17447270" subSource="6yu2_B"/>
      <ConstraintRegion from="348" to="363" loc="H" subId="17447271" subSource="6yu2_B"/>
      <ConstraintRegion from="364" to="383" loc="O" subId="17447272" subSource="6yu2_B"/>
      <ConstraintRegion from="384" to="407" loc="H" subId="17447273" subSource="6yu2_B"/>
      <ConstraintRegion from="408" to="409" loc="I" subId="17447274" subSource="6yu2_B"/>
      <ConstraintRegion from="410" to="415" loc="F" subId="17447275" subSource="6yu2_B"/>
      <ConstraintRegion from="416" to="423" loc="I" subId="17447276" subSource="6yu2_B"/>
      <ConstraintRegion from="424" to="445" loc="H" subId="17447277" subSource="6yu2_B"/>
      <ConstraintRegion from="446" to="448" loc="O" subId="17447278" subSource="6yu2_B"/>
    </Constraint>
    <Constraint source="TOPDB" sourceId="6yu4_A">
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      <ConstraintRegion from="20" to="39" loc="H" subId="17447356" subSource="6yu4_A"/>
      <ConstraintRegion from="40" to="44" loc="O" subId="17447358" subSource="6yu4_A"/>
      <ConstraintRegion from="45" to="64" loc="H" subId="17447360" subSource="6yu4_A"/>
      <ConstraintRegion from="65" to="92" loc="I" subId="17447362" subSource="6yu4_A"/>
      <ConstraintRegion from="93" to="120" loc="H" subId="17447364" subSource="6yu4_A"/>
      <ConstraintRegion from="121" to="133" loc="O" subId="17447366" subSource="6yu4_A"/>
      <ConstraintRegion from="134" to="144" loc="F" subId="17447368" subSource="6yu4_A"/>
      <ConstraintRegion from="145" to="149" loc="O" subId="17447370" subSource="6yu4_A"/>
      <ConstraintRegion from="150" to="167" loc="H" subId="17447372" subSource="6yu4_A"/>
      <ConstraintRegion from="168" to="171" loc="I" subId="17447374" subSource="6yu4_A"/>
      <ConstraintRegion from="172" to="192" loc="H" subId="17447376" subSource="6yu4_A"/>
      <ConstraintRegion from="193" to="215" loc="O" subId="17447378" subSource="6yu4_A"/>
      <ConstraintRegion from="216" to="242" loc="H" subId="17447380" subSource="6yu4_A"/>
      <ConstraintRegion from="243" to="255" loc="I" subId="17447382" subSource="6yu4_A"/>
      <ConstraintRegion from="256" to="273" loc="H" subId="17447384" subSource="6yu4_A"/>
      <ConstraintRegion from="274" to="290" loc="O" subId="17447386" subSource="6yu4_A"/>
      <ConstraintRegion from="291" to="301" loc="F" subId="17447388" subSource="6yu4_A"/>
      <ConstraintRegion from="302" to="308" loc="O" subId="17447390" subSource="6yu4_A"/>
      <ConstraintRegion from="309" to="336" loc="H" subId="17447392" subSource="6yu4_A"/>
      <ConstraintRegion from="337" to="344" loc="I" subId="17447394" subSource="6yu4_A"/>
      <ConstraintRegion from="345" to="363" loc="H" subId="17447396" subSource="6yu4_A"/>
      <ConstraintRegion from="364" to="380" loc="O" subId="17447398" subSource="6yu4_A"/>
      <ConstraintRegion from="381" to="402" loc="H" subId="17447400" subSource="6yu4_A"/>
      <ConstraintRegion from="403" to="422" loc="I" subId="17447401" subSource="6yu4_A"/>
      <ConstraintRegion from="423" to="430" loc="F" subId="17447402" subSource="6yu4_A"/>
      <ConstraintRegion from="431" to="449" loc="H" subId="17447403" subSource="6yu4_A"/>
    </Constraint>
    <Constraint source="TOPDB" sourceId="6yu6_A">
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      <ConstraintRegion from="21" to="36" loc="H" subId="17447495" subSource="6yu6_A"/>
      <ConstraintRegion from="37" to="45" loc="O" subId="17447497" subSource="6yu6_A"/>
      <ConstraintRegion from="46" to="63" loc="H" subId="17447499" subSource="6yu6_A"/>
      <ConstraintRegion from="64" to="89" loc="I" subId="17447501" subSource="6yu6_A"/>
      <ConstraintRegion from="90" to="113" loc="H" subId="17447503" subSource="6yu6_A"/>
      <ConstraintRegion from="114" to="123" loc="F" subId="17447505" subSource="6yu6_A"/>
      <ConstraintRegion from="124" to="151" loc="O" subId="17447507" subSource="6yu6_A"/>
      <ConstraintRegion from="152" to="167" loc="H" subId="17447508" subSource="6yu6_A"/>
      <ConstraintRegion from="168" to="174" loc="I" subId="17447509" subSource="6yu6_A"/>
      <ConstraintRegion from="175" to="193" loc="H" subId="17447510" subSource="6yu6_A"/>
      <ConstraintRegion from="194" to="218" loc="O" subId="17447511" subSource="6yu6_A"/>
      <ConstraintRegion from="219" to="242" loc="H" subId="17447512" subSource="6yu6_A"/>
      <ConstraintRegion from="243" to="256" loc="I" subId="17447513" subSource="6yu6_A"/>
      <ConstraintRegion from="257" to="273" loc="H" subId="17447514" subSource="6yu6_A"/>
      <ConstraintRegion from="274" to="290" loc="O" subId="17447515" subSource="6yu6_A"/>
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      <ConstraintRegion from="309" to="337" loc="H" subId="17447518" subSource="6yu6_A"/>
      <ConstraintRegion from="338" to="342" loc="I" subId="17447519" subSource="6yu6_A"/>
      <ConstraintRegion from="343" to="360" loc="H" subId="17447520" subSource="6yu6_A"/>
      <ConstraintRegion from="361" to="383" loc="O" subId="17447521" subSource="6yu6_A"/>
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      <ConstraintRegion from="403" to="431" loc="I" subId="17447523" subSource="6yu6_A"/>
      <ConstraintRegion from="432" to="448" loc="H" subId="17447524" subSource="6yu6_A"/>
    </Constraint>
    <Constraint source="TOPDB" sourceId="6yu3_A">
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      <ConstraintRegion from="20" to="39" loc="H" subId="17447285" subSource="6yu3_A"/>
      <ConstraintRegion from="40" to="44" loc="O" subId="17447287" subSource="6yu3_A"/>
      <ConstraintRegion from="45" to="67" loc="H" subId="17447289" subSource="6yu3_A"/>
      <ConstraintRegion from="68" to="89" loc="I" subId="17447291" subSource="6yu3_A"/>
      <ConstraintRegion from="90" to="120" loc="H" subId="17447293" subSource="6yu3_A"/>
      <ConstraintRegion from="121" to="133" loc="O" subId="17447295" subSource="6yu3_A"/>
      <ConstraintRegion from="134" to="144" loc="F" subId="17447297" subSource="6yu3_A"/>
      <ConstraintRegion from="145" to="149" loc="O" subId="17447299" subSource="6yu3_A"/>
      <ConstraintRegion from="150" to="168" loc="H" subId="17447301" subSource="6yu3_A"/>
      <ConstraintRegion from="169" to="171" loc="I" subId="17447303" subSource="6yu3_A"/>
      <ConstraintRegion from="172" to="193" loc="H" subId="17447305" subSource="6yu3_A"/>
      <ConstraintRegion from="194" to="218" loc="O" subId="17447307" subSource="6yu3_A"/>
      <ConstraintRegion from="219" to="242" loc="H" subId="17447309" subSource="6yu3_A"/>
      <ConstraintRegion from="243" to="254" loc="I" subId="17447311" subSource="6yu3_A"/>
      <ConstraintRegion from="255" to="274" loc="H" subId="17447313" subSource="6yu3_A"/>
      <ConstraintRegion from="275" to="290" loc="O" subId="17447315" subSource="6yu3_A"/>
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      <ConstraintRegion from="338" to="344" loc="I" subId="17447323" subSource="6yu3_A"/>
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      <ConstraintRegion from="417" to="427" loc="I" subId="17447335" subSource="6yu3_A"/>
      <ConstraintRegion from="428" to="448" loc="H" subId="17447337" subSource="6yu3_A"/>
    </Constraint>
    <Constraint source="TOPDB" sourceId="5jaf_A">
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      <ConstraintRegion from="64" to="92" loc="I" subId="17131770" subSource="5jaf_A"/>
      <ConstraintRegion from="93" to="117" loc="H" subId="17131771" subSource="5jaf_A"/>
      <ConstraintRegion from="118" to="124" loc="F" subId="17131773" subSource="5jaf_A"/>
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      <ConstraintRegion from="191" to="211" loc="H" subId="17131782" subSource="5jaf_A"/>
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      <ConstraintRegion from="279" to="296" loc="H" subId="17131794" subSource="5jaf_A"/>
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      <ConstraintRegion from="501" to="508" loc="I" subId="17131829" subSource="5jaf_A"/>
    </Constraint>
    <Constraint source="TOPDB" sourceId="6xwm_A">
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      <ConstraintRegion from="16" to="35" loc="H" subId="17430179" subSource="6xwm_A"/>
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      <ConstraintRegion from="63" to="92" loc="I" subId="17430182" subSource="6xwm_A"/>
      <ConstraintRegion from="93" to="124" loc="H" subId="17430183" subSource="6xwm_A"/>
      <ConstraintRegion from="125" to="166" loc="O" subId="17430184" subSource="6xwm_A"/>
      <ConstraintRegion from="167" to="183" loc="H" subId="17430185" subSource="6xwm_A"/>
      <ConstraintRegion from="184" to="190" loc="I" subId="17430186" subSource="6xwm_A"/>
      <ConstraintRegion from="191" to="211" loc="H" subId="17430187" subSource="6xwm_A"/>
      <ConstraintRegion from="212" to="222" loc="O" subId="17430188" subSource="6xwm_A"/>
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      <ConstraintRegion from="280" to="297" loc="H" subId="17430193" subSource="6xwm_A"/>
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      <ConstraintRegion from="364" to="379" loc="I" subId="17430198" subSource="6xwm_A"/>
      <ConstraintRegion from="380" to="396" loc="H" subId="17430199" subSource="6xwm_A"/>
      <ConstraintRegion from="397" to="399" loc="O" subId="17430200" subSource="6xwm_A"/>
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      <ConstraintRegion from="429" to="437" loc="F" subId="17430203" subSource="6xwm_A"/>
      <ConstraintRegion from="438" to="447" loc="I" subId="17430204" subSource="6xwm_A"/>
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      <ConstraintRegion from="501" to="510" loc="I" subId="17430209" subSource="6xwm_A"/>
    </Constraint>
    <Constraint source="TOPDB" sourceId="6xwm_B">
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      <ConstraintRegion from="36" to="43" loc="O" subId="17430212" subSource="6xwm_B"/>
      <ConstraintRegion from="44" to="62" loc="H" subId="17430213" subSource="6xwm_B"/>
      <ConstraintRegion from="63" to="92" loc="I" subId="17430214" subSource="6xwm_B"/>
      <ConstraintRegion from="93" to="124" loc="H" subId="17430215" subSource="6xwm_B"/>
      <ConstraintRegion from="125" to="166" loc="O" subId="17430216" subSource="6xwm_B"/>
      <ConstraintRegion from="167" to="183" loc="H" subId="17430217" subSource="6xwm_B"/>
      <ConstraintRegion from="184" to="190" loc="I" subId="17430218" subSource="6xwm_B"/>
      <ConstraintRegion from="191" to="211" loc="H" subId="17430219" subSource="6xwm_B"/>
      <ConstraintRegion from="212" to="241" loc="O" subId="17430220" subSource="6xwm_B"/>
      <ConstraintRegion from="242" to="262" loc="H" subId="17430221" subSource="6xwm_B"/>
      <ConstraintRegion from="263" to="279" loc="I" subId="17430222" subSource="6xwm_B"/>
      <ConstraintRegion from="280" to="297" loc="H" subId="17430223" subSource="6xwm_B"/>
      <ConstraintRegion from="298" to="320" loc="O" subId="17430224" subSource="6xwm_B"/>
      <ConstraintRegion from="321" to="333" loc="F" subId="17430225" subSource="6xwm_B"/>
      <ConstraintRegion from="334" to="339" loc="O" subId="17430226" subSource="6xwm_B"/>
      <ConstraintRegion from="340" to="363" loc="H" subId="17430227" subSource="6xwm_B"/>
      <ConstraintRegion from="364" to="379" loc="I" subId="17430228" subSource="6xwm_B"/>
      <ConstraintRegion from="380" to="396" loc="H" subId="17430229" subSource="6xwm_B"/>
      <ConstraintRegion from="397" to="399" loc="O" subId="17430230" subSource="6xwm_B"/>
      <ConstraintRegion from="400" to="421" loc="H" subId="17430231" subSource="6xwm_B"/>
      <ConstraintRegion from="422" to="428" loc="I" subId="17430232" subSource="6xwm_B"/>
      <ConstraintRegion from="429" to="436" loc="F" subId="17430233" subSource="6xwm_B"/>
      <ConstraintRegion from="437" to="447" loc="I" subId="17430234" subSource="6xwm_B"/>
      <ConstraintRegion from="448" to="469" loc="H" subId="17430235" subSource="6xwm_B"/>
      <ConstraintRegion from="470" to="476" loc="F" subId="17430236" subSource="6xwm_B"/>
      <ConstraintRegion from="477" to="483" loc="O" subId="17430237" subSource="6xwm_B"/>
      <ConstraintRegion from="484" to="500" loc="H" subId="17430238" subSource="6xwm_B"/>
      <ConstraintRegion from="501" to="507" loc="I" subId="17430239" subSource="6xwm_B"/>
    </Constraint>
    <Constraint source="TOPDB" sourceId="7djc_A">
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      <ConstraintRegion from="16" to="32" loc="H" subId="17033337" subSource="7djc_A"/>
      <ConstraintRegion from="33" to="41" loc="O" subId="17033338" subSource="7djc_A"/>
      <ConstraintRegion from="42" to="63" loc="H" subId="17033339" subSource="7djc_A"/>
      <ConstraintRegion from="64" to="88" loc="I" subId="17033340" subSource="7djc_A"/>
      <ConstraintRegion from="89" to="124" loc="H" subId="17033341" subSource="7djc_A"/>
      <ConstraintRegion from="125" to="132" loc="O" subId="17033342" subSource="7djc_A"/>
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      <ConstraintRegion from="186" to="190" loc="I" subId="17033345" subSource="7djc_A"/>
      <ConstraintRegion from="191" to="214" loc="H" subId="17033346" subSource="7djc_A"/>
      <ConstraintRegion from="215" to="222" loc="O" subId="17033347" subSource="7djc_A"/>
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      <ConstraintRegion from="242" to="265" loc="H" subId="17033351" subSource="7djc_A"/>
      <ConstraintRegion from="266" to="279" loc="I" subId="17033352" subSource="7djc_A"/>
      <ConstraintRegion from="280" to="298" loc="H" subId="17033353" subSource="7djc_A"/>
      <ConstraintRegion from="299" to="318" loc="O" subId="17033354" subSource="7djc_A"/>
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      <ConstraintRegion from="340" to="367" loc="H" subId="17033359" subSource="7djc_A"/>
      <ConstraintRegion from="368" to="376" loc="I" subId="17033360" subSource="7djc_A"/>
      <ConstraintRegion from="377" to="394" loc="H" subId="17033361" subSource="7djc_A"/>
      <ConstraintRegion from="395" to="399" loc="O" subId="17033362" subSource="7djc_A"/>
      <ConstraintRegion from="400" to="425" loc="H" subId="17033363" subSource="7djc_A"/>
      <ConstraintRegion from="426" to="428" loc="I" subId="17033364" subSource="7djc_A"/>
      <ConstraintRegion from="429" to="437" loc="F" subId="17033365" subSource="7djc_A"/>
      <ConstraintRegion from="438" to="447" loc="I" subId="17033366" subSource="7djc_A"/>
      <ConstraintRegion from="448" to="469" loc="H" subId="17033367" subSource="7djc_A"/>
      <ConstraintRegion from="470" to="473" loc="O" subId="17033368" subSource="7djc_A"/>
      <ConstraintRegion from="480" to="484" loc="O" subId="17033369" subSource="7djc_A"/>
      <ConstraintRegion from="485" to="503" loc="H" subId="17033370" subSource="7djc_A"/>
      <ConstraintRegion from="504" to="508" loc="I" subId="17033371" subSource="7djc_A"/>
    </Constraint>
  </Constraints>
</HtpItem>
