Welcome to the Human Transmembrane Proteome database

The Human Transmembrane Proteome database and web service are comprehensive resources of the α-helical human transmembrane proteins. It contains topology and structure information about the human α-helical transmembrane proteins classified into reliability levels. First level is proteins with known 3D structures, second level is proteins with experimentally established topology, third level is proteins with conservatively appearing domains or motifs on one side of the membrane, fourth is proteins proved to be exists, and the last level contains proteins predicted from the annotated human genome database.

The UNIfied database of TransMembrane Proteins (UniTmp) is a comprehensive and freely accessible resource of transmembrane protein topology and structural information. UniTmp bridges the gap between TOPDB (Topology Data Bank of Transmembrane Proteins), TOPDOM (database of conservatively located domains and motifs in proteins), PDBTM (Protein Data Bank of Transmembrane Proteins) and HTP (Human Transmembrane Proteome) databases. These resources stand for over 10 years by now and they provide structural information at different levels. The goal of UniTmp was to serve a solid background for all this information, by integrating these resources using a shared SQL based database. This way UniTmp provides up-to-date and consistent data, while keeping up the old usual interface of the original websites.