HTP

Visitors:	312927
# of TMPs:	15327
Server version:	v2.0.0
Database release:	d.2.2
Release date:	22.07.2024

HTP viewer for A0A0A0MSA1_HUMAN

A0A0A0MSA1_HUMAN

Voltage-dependent L-type calcium channel subunit alpha

Evidence:

Exists

Reliability:

72.11

# of TM segments:

Cross ref(s)::

UniProt: A0A0A0MSA1_HUMAN
PDBTM: 8hlp, 8hma, 8hmb
TOPDB: A0A0A0MSA1_HUMAN

MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAAL
SWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRP
PRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPED
DSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDF
IIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSG
VPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFA
FAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLV
LGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPE
NEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKS
KFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPN
WLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRS
IASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVF
QILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLA
IAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESK
EEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEE
PEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIAL
KMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQL
FKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDN
VLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYI
IIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIA
MNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
SETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLL
WTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQ
TFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS
FAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI
WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL
NSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL
LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALS
LQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAG
GLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVD
STFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP
AIRVQEVAWKLSSNRERHVPMCEDLELRRDSGSAGTQAHCLLLRRANPSR
CHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDE
NRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDIS
QKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWP
PQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVS
LMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELAD
ACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAG
CVRARGRPSEEELQDSRVYVSSL

Legend: Inside Membrane Outside Re-entrant loop Beta barrel inside Periplasm Interfacial helix

A0A0A0MSA1_HUMAN

Legend: Inside Membrane Outside Re-entrant loop Beta barrel inside Periplasm Interfacial helix