Visitors: | 389103 |
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# of TMPs: | 15327 |
Server version: | v2.0.0 |
Database release: | d.2.2 |
Release date: | 22.07.2024 |
HTP viewer for HECD4_HUMAN
HECD4_HUMAN
Probable E3 ubiquitin-protein ligase HECTD4
Evidence:
Exists
Reliability:
61.13
# of TM segments:
10
Cross ref(s)::
UniProt: HECD4_HUMAN
MPANHLPIGSTMSTVHLSSDGTYFYWIWSPASLNEKTPKGHSVFMDIFEL VVENGVFVANPLQERTILMRKEGESAKSINEMLLSRLSRYRASPSATLAA LTGSTISNTLKEDQAANTSCGLPLKMLRKTPIYTCGTYLVMLVPPPGGSG SSATRSLFGGTSGLSSLKRACYDTVNNMLWTCSNDYIDQWCNPGNQAFHY VCQRLGVSHIITEPKEEAITTNEVINQLLHHVGAMCIHQLNLLATNPNLP ITSVLGKQHPIEAHHLSSICDIMEKAMVNGDTCIIRCILVVFQVVFKFFF SPQTERNRDIIRRSGLLLWQLLMAPKDQICPEIQKEVCLAISSGLNILYP GETEINNLLKLVLTEGERNSGLSQLRDVILTNLAEQLQNNRFGSDEDDHY RLNDELLHYILKIVVRESCILITKCQTVSKDDFQKLLSTVPAASSCLRYL MAVQNHLLSNTILIKPDENDDSDSSLQGETLKVQELKVSILALATQILTG CDEVLEMLQQVTTALINSDIADREQRLKGLEQVTKATMLGHLLPVLLTSL MHPNLQTLIMADALMPQLVQLVLYTSQTALLLKTQCPVFAEVGCSPCGAP DQKCRLFPDERMLEEKEEPGFLTGLKIPAPWAAGKTVETVHPVRDNYKFK ETVHIPGARCLYLRFDSRCSSQYDYDKLVIYAGPNTNSRKVAEYGGNTLG YGSRSVLGTGWPKDLVKCISPPSLNFKVEGDTVTFSFEMRSGREHNTPDK AMWGFACTVRAQESSEDVSGGLPFLVDLALGLSVLACSMLRILYNGPEIT KEEEACQELLRSKLLQRCQWQVEANGVISPALTPSPSPLPLTIEEDREFT YPSDVLVPPVGNYFDLPRIRLPPGIMIKLREISGRARPQFRPSIKEVIQP DVMEEMVVSCVIKHLNLVDALQSLINFQYQEEHAEEYDLLCKIMGETFKK LNAMERQLQSVAELEQKWQSEVDDAMQGKLENNMPFFYDYHFNENKMKEL ELLCSMKEVSFDGNDLENMVLSLREKFLQEVNSLIQKPSHPLAKTKTLVK SLMNRAELLLHVTIAAQSGLTRSISGTPAETPACKSASETKVISHAVRQP VFLRSMSAPSDLEMIGNEDLEFTRANQRRRHVTSHRSSSFTLLQSLAIED SRDKPTYSVLLGQLFAFIGTNPDQAVSSSSFLLAAQTRWRRGNTRKQALV HMRELLTAAVRVGGVTHLVGPVTMVLQGGPRIEELTCGGMVEQVQEAFGE TMTSVVSLCARYPIACANSIGLLCTIPYTRSEEKCLVRSGLVQLMDRLCS LSNQTESSSSEKQTKKQKVATMAWAAFQVLANRCVEWEKEEGGSTEAVHS GLARQVSSLLTNHLARATECCGNQAAGNDALQDVLSLLNDLSRSHIGKAI LSQPACVSKLLSLLLDQRPSPKLVLIILQLCRAALPLMSVEDCGNVELPP WSYSVPSLNSEQEDPSDPASKIASLLLAKLADYVVPGCQTVLSPTASEPD TTLTKTSPKNSLKGDKDPGEESEAVDGKLSIFIHKREDQSSHEVLQPLLS SSEGRPFRLGTGANMEKVVKMDRDMTKGGCCEVITEEAAAALRKATKWAQ SGLIVSIGPPVESINPETVSGLSTGDKKKTAQTSICRERNSELARTDPVR PFISGHVANSMAAEVIALLHSLLMAPESNAAQIWTTTAEKVLSRALMYIP QLGKYAESILENGSSSGRKLAKLQRIARQAVAALCALGGFKETIKIGSEV QVLGRGISGSIGVVASINEQEGIATVRFPPIDCRKTSQASDTLTIPLSRL CVPRSEALPLHKLSITEKVVQAVQSMLLPQEGSLSIHTSLPATGDGSAPV MAVVRLLAEIRTRACLVMAQLLEDSLFCEEFIQQCPAAVEVLNLVAQECS AGERLAVVEVQCERLRMLYRDCARPPPPPLQADRRQPKEITWSPSRVFPP VRACMFSSHLTSVTFLADPSAGGGLPRGTFIYATSPLPVQAPSFYWEIEI VSYGDTDDDTGPIVSFGFTTEAEKRDGAWTNPVGTCLFHNNGRAVHYNGS SLLQWKSVRLDVTLSPGDVAGIGWERTEGTPPPPGQPAKGRVYFTYCGQR LSPYLEDVSGGMWPVVHIQKKNTKTRANFGSRPFAYAEGQAHRNAADLCT DLAEEISANFEALPFAMASDSDNDAGTSIASDPGTHGPPCRIAAVATAQQ QYDSDTSCHYKVELSYENFITSGPDPHPPPIADDESDDDDDDDIPQEDHY ALLVKAWETKVFPTIRRRFRNEAERKSGLDQIKGALQLGMVDIARQTVEF LYEENGGIPRDLYLPTIEDIKDEANKFTIDKVRKGLTVVTRSPDSNNVAS SAVGTALPKFAIRGMLKTFGLHGVVLDVDSVNELVQVETYLRSEGVLVRY WYPIDMLERPPAGYRRTATNGLVTLDNTNLQIHRELLRCEAALARLYCRM ALLNIFAPKLPHLFTRLFHIPAIRDITLEHLQLLSNQLLAPPLPDGTISS SSILLAQSLQHCIHSQNCSATDLFYQGNSQTVREWLNVAITRTLHQGEES LLELTKQICSFLQTAPEQFPSEEFPISESKVNMDVNFPGAAFVVVSCKES QSGFRKDSSLYKAPWARVLVYGLGHKVKRNGQLNLIEAACYPRDASPANT GLAPPPTADQYPSVVLSTDRVHIKLGVSPPPGAVLVLHSLPLEFPLAMAF AEQLLSWKSEDSEGKSEDEPDTIPTSVLLQVVELLGNFLWTTDMAACVKE LVFHLLAELLRTVHTLEQRRHPAGLSSSIALQLNPCLAMLMALQSELHKL YDEETQNWVSGGACGGSGGAAAGDQGRFSTYFHALMEGCLAVAEVTLPTN MSVTASGVTSATAPNLSDSSSSSSSSPGQTPQSPSLLSKRKKVKMKREKA SSSGKRQSSRTVDSDPTVLSIGGSKPEDMLWFHRALTLLIILRHLTRKDP QGLGVTSDAIADACQALVGPTAHSRLLVISGIPTHLDEGVVRGAIRKACN AHGGVFKDEIYIPLQEEDTKKPKDKAEGGDGKVEPEKTLAFPGTDSMEVS TSSSLTPAMSISASASTSQASICSSQGISQTVSDLSVDPLPAGLELPIPP GLLEPHAVSSQESLDISLCSTGSLGSLGSLGEPLDNAETASVSDMGSMYT VTSLDNQPLAARPIKGFAVVEIRSRAKIEKIRASLFNNNDLIGLSSLDGE DELMEMSTEEILTVSVVNQSLFDTQGSPGLEDYFNDKSIKGEKLVPGARE VLTEIFKSCAHSEQTLSLTPAKPIRVSDIYLSKEQINSQTPGNLLHLFFT NVRPPKKVLEDQLTQILRKYGVPKPKFDKSKYSKAGKEQHPVKVVSTKRP ITKPPAKDKAVLNSVSRTALSEKKPTVKPKSPEKSKPDEKDPEKSPTKKQ EVPEEKYLTLEGFHKFVIDRARQDIRSVWRAILSCGYDLHFERCACIDVR HAQKASRKWTLEMDVALVQYINQLCRHLAITPARLHPHEVYLDPADAADP RVACLLNVPIESLRLRFALLQSLNTTLETFFLPLVELRQTPMYTHSIAAL LKEAKGLIFYDTKVTVMNRVLNATVQRTADHAAPEITLDPLEIVGGEIRA SENSYFCQAARQLASVPSSQLCVKLASGGDPTYAFNIRFTGEEVHGTSGS FRHFLWQVCKELQSSSLSLLLLCPSSAVNKNKGKYILTPSPITYGEEQLL HFLGQLLGIAIRADVPLPLDLLPSFWKTLVGEPLDPEQDLQEADILTYNY VKKFESINDETELEALCAEIASQHLATESPDSPNKPCCRFTYLTMTGEEV ELCSRGRHILVAWENKDIYAAAIRSLRLRELQNVECVTAVRAGLGSIIPL QLLTMLSPLEMELRTCGLPYINLEFLKAHTMYQVGLMETDQHIEFFWGAL EMFTQEELCKFIKFACNQERIPFTCPCKDGGPDTAHVPPYPMKIAPPDGT AGSPDSRYIRVETCMFMIKLPQYSSLEIMLEKLRCAIHYREDPLSG
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix