| Visitors: | 411957 |
|---|---|
| # of TMPs: | 15327 |
| Server version: | v2.0.0 |
| Database release: | d.2.2 |
| Release date: | 22.07.2024 |
HTP viewer for R1A_CVHN2
R1A_CVHN2
Replicase polyprotein 1a
Evidence:
TOPDOM
Reliability:
86.34
# of TM segments:
10
Cross ref(s)::
UniProt: R1A_CVHN2
MIKTSKYGLGFKWAPEFRWLLPDAAEELASPMKSDEGGLCPSTGQAMESV GFVYDNHVKIDCRCILGQEWHVQSNLIRDIFVHEDLHVVEVLTKTAVKSG TAILIKSPLHSLGGFPKGYVMGLFRSYKTKRYVVHHLSMTTSTTNFGEDF LGWIVPFGFMPSYVHKWFQFCRLYIEESDLIISNFKFDDYDFSVEDAYAE VHAEPKGKYSQKAYALLRQYRGIKPVLFVDQYGCDYSGKLADCLQAYGHY SLQDMRQKQSVWLANCDFDIVVAWHVVRDSRFVMRLQTIATICGIKYVAQ PTEDVVDGAVVIREPVHLLSADAIVLKLPSLMKVMTHMDDFSIKSIYNVD LCDCGFVMQYGYVDCFNDNCDFYGWVSGNMMDGFSCPLCCTVYDSSEVKA QSSGVIPENPVLFTNSTDTVNPDSFNLYGYSVTPFGSCIYWSPRPGLWIP IIKSSVKSYDDLVYSGVVGCKSIVKETALITHALYLDYVQCKCGNLEQNH ILGVNNSWCRQLLLNRGDYNMLLKNIDLFVKRRADFACKFAVCGDGFVPF LLDGLIPRSYYLIQSGIFFTSLMSQFSQEVSDMCLKMCILFMDRVSVATF YIEHYVNRLVTQFKLLGTTLVNKMVNWFNTMLDASAPATGWLLYQLLNGL FVVSQANFNFVALIPDYAKILVNKFYTFFKLLLECVTVDVLKDMPVLKTI NGLVCIVGNKFYNVSTGLIPGFVLPCNAQEQQIYFFEGVAESVIVEDDVI ENVKSSLSSYEYCQPPKSVEKICIIDNMYMGKCGDKFFPIVMNDKNICLL DQAWRFPCAGRKVNFNEKPVVMEIPSLMTVKVMFDLDSTFDDILGKVCSE FEVEKGVTVDDFVAVVCDAIENALNSCKDHPVVGYQVRAFLNKLNENVVY LFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDDEDV VTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDV VTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDV VTGDNDDEEIVTGDNDDQIVVTGDDVDDIESVYDFDTYKALLVFNDVYND ALFVSYGSSVETETYFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDL AIENMWLSYKVGYNQSFVDYLLTTIPKAIVLPQGGYVADFAYWFLNQFDI NAYANWCCLKCGFSFDLNGLDAVFFYGDIVSHVCKCGHNMTLIAADLPCT LHFSLFDDNFCAFCTPKKIFIAACAVDVNVCHSVAVIGDEQIDGKFVTKF SGDKFDFIVGYGMSFSMSSFELAQLYGLCITPNVCFVKGDIINVARLVKA DVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMVKSKGVCQVGDCYV STGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLISAG IFSVPADVSLTYLLGVVDKQVILVSNNKEDFDIIQKCQITSVVGTKALAV RLTANVGRVIKFETDAYKLFLSGDDCFVSNSSVIQEVLLLRHDIQLNNDV RDYLLSKMTSLPKDWRLINKFDVINGVKTVKYFECPNSIYICSQGKDFGY VCDGSFYKATVNQVCVLLAKKIDVLLTVDGVNFKSISLTVGEVFGKILGN VFCDGIDVTKLKCSDFYADKILYQYENLSLADISAVQSSFGFDQQQLLAY YNFLTVCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQHINLKFNKWQWQE AWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAICE LELICDCGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIVHCTK LNVPFLICSNTPLSKDLPDDVVAANMFMGVGVGHYTHLKCGSPYQHYDAC SVKKYTGVSGCLTDCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYY CDNGKYYTKPIIKAQFKPFAKVDGVYTNFKLVGHDICAQLNDKLGFNVDL PFVEYKVTVWPVATGDVVLASDDLYVKRYFKGCETFGKPVIWLCHDEASL NSLTYFNKPSFKSENRYSVLSVDSVSEESQGNVVTSVMESQISTKEVKLK GVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDMYLTGCDYVVWVANEL SRLVKSPTVREYIRYGIKPITIPIDLLCLRDDNQTLLVPKIFKARAIEFY GFLKWLFIYVFSLLHFTNDKTIFYTTEIASKFTFNLFCLALKNAFQTFRW SIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIK ATFGLVTICDFYSKLGVGFTSHFCNGSFICELCYSGFDMLDTYAAIDFVQ YEVDRRVLFDYVSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPD LFMLETMHWLIRFIVFVANMLPAFVLLRFYIVVTAMYKVVGFIRHIVYGC NKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITANGGTGFCVKHQWNCFN CHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVGCMMRLF YDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVESDADRANFLN AVVFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDR KSFNNFVNIAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSM ISAVAAGLEFTDENYNNLVPTYLKSDNIVAADLGVLIQNGAKHVQGNVAK AANISCIWFIDTFNQLTADLQHKLKKACVKTGLKLKLTFNKQEASVPILT TPFSLKGGVVLSNLLYILFFISLICFILLWALLPTYSVYKSDIHLPAYAS FKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSFYYHNSMDCPIVVA VMDEDIGSTMFNVPTKVLRHGFHVLHFLTYAFASDSVQCYTPHIQISYND FYASGCVLSSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLA NSNGFIRFPDVISEGIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVL NNDYYRSMPGTFCGRDLFDLFYQFFSSLIRPIDFFSLTASSIFGAILAIV VVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPICACVYA CFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIANHVLWL FSYCRKIGVNVCNDSTFEETSLTTFMITKDSYCRLKNSVSDVAYNRYLSL YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVST SFLQSGIVKMVSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICLS SNMNEPDYSALLCRVTLGDFTIMSGRMSLTVVSYQMQGCQLVLTVSLQNP YTPKYTFGVVKPGETFTVLAAYNGRPQGAFHVTMRSSYTIKGSFLCGSCG SVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYRDAQVVQLPVK DYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADL VLDALASMTGVSIETLLAAIKRLYMGFQGRQILGSCTFEDELAPSDVYQQ LAGVKLQSKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYINTHMIG VTLCVLCFVSFMMLLVKHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGL TYVWLSYFVPAVNFTYVYEVFYGCILCVFAIFITMHSINHDIFSLMFLVG RIVTLISMWYFGSNLEEDVLLFITAFLGTYTWTTILSLAIAKIVANWLSV NIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPMGVYNYKI SVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDV KCANVVLLNCLQHLHVASNSRLWQYCSILHNEILSTSDLSVAFDKLAQLL IVLFANPAAVDTKCLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEV AKKNLADAKNSGSVNQQQIKQLEKACNIAKSVYERDKAVARKLERMADLA LTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVP LNAIPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQTVQDADGIN KQLTDISVDSNWPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSDM NCNIPTQCYYNNGSSGRIVYAVLSDVDGLKYTKIIKDDGNCVVLELDPPC KFSIQDVKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAAN SSILSLCAFSVDPKKTYLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPE ATINQDSYGGASVCIYCRARVEHPDVDGLCKLRGKFVQVPLGIKDPILYV LTHDVCQVCGFWRDGSCSCVGSGVAVQSKDLNFLNGFGVLV
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
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Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix