A0A3B3IRP0_HUMAN
Inositol 1,4,5-trisphosphate receptor type 1
XVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLF
LNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFL
QTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSER
DRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHE
DCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACN
NTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLL
QGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLF
LKSHSIVQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALED
RLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQL
LEENEEKLCIKVLQTLREMMTKDRGYGEKLISIDELDNAELPPAPDSENA
TEQELEPSPPLRQLEDHKRGEALRQVLVNRYYGNVRPSGRRESLTSFGNG
PLSAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIM
NASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDR
MKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVR
DQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVI
TIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGS
TTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGI
DIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERIL
YNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYILAHQL
ARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVP
SICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQ
PVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGALPFEGFQKGR
GTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQP
TLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVIC
AMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILV
YLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESG
ENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDV
LRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQK
KEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKD
STEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKL
ESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLLGHPPHMNVNPQQPA
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
