A0A3B3IU05_HUMAN
Inositol 1,4,5-trisphosphate receptor type 1
XLLAILDCVHVTTIFPISKMAKGEENKGSNVMRSIHGVGELMTQVVLRGG
GFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYR
ISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEG
IFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQ
RQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGP
DETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQ
ESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHE
FLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINE
RVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGE
DVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKN
VYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKE
IYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTF
FSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVL
SDVAKSRAIAIPVDLDSQVNNLFLKSHSIVQKTAMNWRLSARNAARRDSV
LAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPEN
TDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYG
EKLISIDELDNAELPPAPDSENATEELEPSPPLRQLEDHKRGEALRQVLV
NRYYGNVRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGEMS
LAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQH
SFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEV
DRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQ
PGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQ
NNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLT
EYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNN
ASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGEN
GEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAK
HTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKIN
DFFLRSEDLFNEMNWQKKLRGTLEPHWSGLLWTAMLISLAIVIALPKPHG
IRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRG
YRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIK
SVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPE
TGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLL
MCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVL
NLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHI
KEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMS
LVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQR
IGLLGHPPHMNVNPQQPA
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
