A0A8P0S728_CANLF
Inositol 1,4,5-trisphosphate receptor
Cross ref(s)::
UniProt:
A0A8P0S728_CANLF
PDBTM:
8tkf,
8ear,
8tkd,
8tke,
8eaq,
7lhf,
7lhe,
8tkg,
8tk8,
8tkh,
8tki,
6dr0,
6dqs,
6dqv,
6dqz,
6dr2,
6dra,
6drc,
6dqn,
6dqj,
7t3r,
7t3t,
8tl9,
8tla,
7t3q,
7t3u
MERDFLEASLVPWHPLPWGDGVFPPTDRAALSLRLVDDRCVVEPAAGDLD
NPPKKFRDCLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHA
AQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKN
AMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQPLHA
SNYELSDNVGCKEVNSVNCNTSWKINLFMQFRDHLEEVLKGGDVVRLFHA
EQEKFLTCDEYKGKLQVFLRTTLRQSATSATSSNALWEVEVVHHDPCRGG
AGHWNGLYRFKHLATGNYLAAEENPSYKGDVCEPKAAGMGRIGRRNAGEK
IKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQ
STNVPIDIEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDAS
SMLASAVEKLNEGFISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVT
KPNRERQKLMREQNILKQIFGILKAPFRDKGGEGPLVRLEELSDQKNAPY
QHMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQSQIGYDILAEDTITALL
HNNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNHIAIAVTQ
ELICKCVLDPKNSDILIQTELRPVKEMAQSHEYLSIEYSEEEVWLTWTDK
NNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAID
EISQQLGVDLIFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVKF
ARLWTEIPTAITIKDYDSNLNASRDDKKNKFASTMDFVEDYLNNVVSEAV
PFANEEKNKLTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCVQGPP
AMLQAYDDSGGKNVRRSIQGVGHMMSTMVLSRKQSVFGAPSLSGGTGATE
PLDRSKFENNEDIVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFV
EVFPMQDSGADGTAPAFDSTTANMNLDRIGEQAEAMFGVGKTSSMLEVDD
EGGRTFLRVLIHLTMHDYAPLVSGALQLLFKHFSQRQEAMHTFKQVQLLI
SAQDVENYKVIKSELDRLRTMVEKSELWVDKKGSGKGEEVDTGAAKDKKE
RPTDEEGFLHPPGEKSSENYQIVKGILERLNKMCGVGEQMRKKQQRLLKN
MDAHKVMLDLLQIPYDKGDAKMMEILRYTHQFLQKFCAGNPGNQALLHKH
LHLFLTPGLLEAETMQHIFLNNYQLCSEISEPVLQHFVHLLATHGRHVQY
LDFLHTVIKAEGKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMM
KAARDGVEDHSPLMYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVSV
VTHEDCITEVKMAYVNFVNHCYVDTEVEMKEIYTSNHIWTLFENFTLDMA
RVCSKREKRLADPTLEKYVLTVVLDTINAFFSSPFSENSTSLQTHQTIVV
QLLQSTTRLLECPWLQQQHKGSVEACIRTLAMVAKGRAISLPMDLDAHIS
SLLSSSASCVAAAQRNASNYKAATRAFPRVTPTANQWDYKNIIEKLQDII
TALEERLRPLVQAELSVLVDVLHWPELLFLEGSEAYQRCESGGFLSKLIQ
HTKDLMESEEKLCVKVLRTLQQMLLKKAKYGDRGNQLRKMLLQNYLQNRK
SSSRGDLPDPMGTGLDQDWSAIAATQCRLDKEGATKLVCDLITSTKNEKI
FQESIGLAIRLLDGGNTEIQKSFYNLMMTDKKSERFFKVLHDRMKRAQQE
TKSTVAVNMNDLGSQPREDREPAGPTTKGRVASFSMPGSPSRYSLGPSLR
RGHEVGERVQSNEMGMSVLIMQPILRFLQLLCENHNRDLQNFLRSQNNKT
NYNLVCETLQFLDIMCGSTTGGLGLLGLYINEDNVGLVIQTLETLTEYCQ
GPCHENQTCIVTHESNGIDIITALILNDISPLCKYRMDLVLQLKDNASKL
LLALMESRHDSENAERILISLRPQELVDVIKKAYLQEDERENSEVSPREV
GHNIYILALQLSRHNKQLQHLLKPVKRIQEEEAEGISSMLSLNNKQLSQM
LKSSAPAQEEEEDPLAYYENHTSQIEIVRQDRSMEQIVFPVPGICQFLTE
ETKHRLFTTTEQDEQGSKVSDFFDQSSFLHNEMEWQRKLRSMPLIYWFSR
RMTLWGSISFNLAVFINIIIAFFYPYMEGASTGVLGSPLISLLFWILICF
SIVALFTKRYSIRPLIVALILRSIYYLGIGPTLNILGALNLTNKIVFVVS
FVGNRGTFIRGYKAMVMDVEFLYHVGYILTSVLGLFVHELFYSILLFDLI
YREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFILEV
DRLPGNHSGASPLGMPHGAATFVGTCSGDQLNCDSGVSVPEVLEGNEELE
STERACDTLLMCIVTVMNHGLRNGGGVGDILRKPSKDESLFPARVVYDLL
FFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFD
NKTVSFEEHIKFEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNL
DWFPRMRAMSLVSNEGEGEQNEIRILQDKLNSTMKLVSHLTAQLNELKEQ
MTEQRKRRQRLGFVDVQNCMSR
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Structure of
Related structures:
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
