A2MG_THEMA
Alpha-2-macroglobulin
MGMKRLIFLVFLLISFSLFGGYAYFSRYPVLHPDEGLSFVISDLENITLN
VWKISEEDFLKAVFDPESFNFSLLEITRPIYSKKFSSEEWKEFSFPLKDR
GFYFATLVSNEGTVFRRVIDRSLFIVTDLEAIYFSDSEKLRLHVFDSDGD
FVEGAEVLLFEDSKLIDRVFTGKDGVVSITKHFDTFYIRYGDSRFFGGVY
FSGGGLEREKLFFVTDRPIYKPSDTVHFRGQIFSFEEGLYKAFEKTKVTV
SIFDTKKNEVYRSEFETDELGGFSGSMKLPDTASVGLYKVNVDHGGRRYY
EYFLVEEYRKPEYKVEIETDKDVYISGEVVNYLVRVKYFNGQPVAKAQVA
YYVRAFPEEGSGYLVYRGTDFTDEEGNLRLGVKTEEGFQGSYRLEVIVTD
ESQRQIEETRSVKVYADNVLISPLDRYVSTSPGKQVRVKVKVTDLSGNPL
NGLLTTSSEDSTSTVAVENGEAIVTFTPKEPKSYRIELSFGKANTHFYVY
AYCGAGTSSEFVINPATNTVKPGDELSVQILAPGKVMGVLGIVSNRVYDT
IPVSFTGSVNLRVRIPKDIPEKNLFISFVGLDDNGRIYKLERLNVLLDTN
FTTMKILFDKDQYEPGEMAQITIESNVDRVCLFLVDEAIYAMVGAEPPVL
ENFLYPYMNYPRTRGGFPHYWRLYVSRNSFRNKLASLPEEKTFADFKQNA
LPSKLNVREYFPDTALWIPSLKLHNGTARVSFKVPDSITSFRATAYGFSK
DRFSQTESEMVVSKKFYLMPHLPSFLRESDVIKISATVFNRTSKTLPVQL
TVELPENIELLEGSSSRHFLMEANSSHTETWTVKAVSASEGSFVKFVAVG
EDLNDAVSMRLPVERFAFEREFYRIMLLDGKETLEIPGQFISSRIRFLDS
IVPLVEDSLKRLIDFPYGCVEQTMSRFFPAVVAASAGIEVENLEEIIQRG
LFKLYSYQHNDGGWGWFRFGESDDFMTCYVMEGLYFTMKAGYDVAESVLQ
RGIEYLRKHPSAYGSYVLDLYGVNHEPFKPESEADLVFLSLSSKEALKQL
MNYVVQDEQKAYLNVYSNNPLISEIQLNSVFLRALAKWKEFPELERKVTN
YLLLKKDSAFWTSTKDTSFVILALLEAMPEYASTTLKVINSENTFELKPG
EERSLVPGSLTVSGKGIVEVEVVYIEVPKEAVSEGLEIKREFYKRYELLI
EENKMIVDAFVPIGRGYVPRSIHPVEKEQTEELYILPYKYWKKTIEYRGV
PLEINGAEVKIKGETYTFFRIETFNGLILVFFRNEALIYDTEKNTITRYL
DVTDAGFMRSGPVFLMKGFVLVGDEKIPVPEDVTGLSCTMDEILLRGENK
TYWYRNGEFVDLPFVARRVFFWDGKKLVAENIRFSGSSKTLRNRVFEVVF
DVGDVKIELGDIIKTVVRVKGDGNYLIVEDFIPSCAQVLSNYREKGIEEN
KFSYSWYSSWNAWYSGREIRTDRVALFARYLYGNSFDYVWRATAEGVFHL
LPARVYPMYSRGLYAHTDPDVLFIGADFIDGRDDQP
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
