BIG3_MOUSE
Brefeldin A-inhibited guanine nucleotide-exchange protein 3
MEEILRKLQRDASGSKYKAIKESCTWALETLGGLDTVVKIPPHLLREKCL
LPLQLALESKNVKLAQHALAGMQKLLSEERFVSMETDSDEKQLLNQILNA
VKVTPSLNEDLQVEVMKVLLCITYTPTFDMNGSAVLKIAEVCIETYTCSC
HQRSINTAVRATLSQMLGDLTLQLRQRQENTIIENPDAPQEFRSQGLTVE
ALCDDVISVLAVLCEKLQASINDSQQLQLLYLECILSVLSSSSSSMHLHR
GFTDLIWKSLCPALVVILGNPIHDKTITSAHSTSTSTSMESDSASLGVSD
HGRGSGCSCTAPTLSGPVARTIYYLAAELVRLVGSVDSMKPVLQSLYHRV
LLYPPPQHRVEAIKIMKEILGSPQRLYDLAGPSSIESEPRKRSISKRKSH
LDLLKLIMDGMTEACIKGGIEACYAAVSCVCTLLGALDELSQGKGLNDTQ
VQQLLLRLEELRDGAESSRDSMEINEADFRWQRRVLSSEHTPWESGNERS
PDISISVTTDTGQTTLEGELGQTTPEDHKNGLKSPAIQEGKGTMGKVSEP
EAIDQPDVVQRSHTVPYPDITNFLSVDCRTRSYGSRYSESNFSVDDQDLS
RTEFDSCDQYSMAAEKDSGRSDVSDIGSDNCSLADEEQTPRDYIGHRSLR
TAALSLKLLKNQEADQHSARLFIQSLEGLLPRLLALSSVEEVDSALQNFA
STFCSGMMHSPGFDGGSSLSFQMLMNADSLYTAAHCALLLNLKLSHGDYY
RKRPTVAPGMMKEFMKQVQTSGVLMVFSQAWLEELYHQVLDRNMLGEAGY
WGSPEDNSLPLITMLTDIDGLESSAIGGQLMASASVESPFTQSRRLDDST
VAGVAFARYILVGCWKNLIDTLSTPLTGRMAGSSKGLAFILGAEGIKEQN
QKERDAICMSLDGLRKAARLSCALGVAANCASALAQMAAASCVQEEKEER
QSQEPSDALAQVKLKVEQKLEQMGKVQGVWLHTAHVLCMDAILSVGLEMG
SHNPDCWPHVFRVCEYVGTLEHTHFSDGISQPPLTIHQPQKTSGSSGLLG
EIEFKSSSQEQSLEQGPSLNTAPVVQPHSIQELVRECSRGRTSDFRGGSL
SGNSAAKVVLSLSTQADRLFDDATDKLNLTALGGFLYQLKKASQSQLFHS
VTDTVDYSLTMPGEVKSTQDQKSALHLFRLGDAMLRIVRSKARPLLHVMR
CWSLVAPHLVEAACHKERHVSQKAVSFIHDILTEVLTDWSEPPHFHFNEA
LFRPFERIMQLELCDEDVQDQVVTSIGELVEVCSAQIQSGWRPLFSALET
VRSGNKSEVKEYLVGDYSMGKGQAPVFDVFEAFLNTDNIQVFANAATSYI
MCLMKFVKGLGEVDCKEIGDCVPGAGATSTDLCLPALDYLRRCSQLLAKI
YKMPLKPIFLSGRLASLPRRLQEQSASSEDGIESVLSDFDDDTGLIEVWI
ILLEQLTAAVSNCPRQHQPPTLDLLFELLRDVTKTPGPGFGIYAVVHLLL
PVMSLWLLRSHKDHSYWDVASANFKHAIGLSCELVVEHIQSFLHSDIRYE
SMINTMLKDLFELLVVCVAKPTETISRVGCSCIRYVLVTAGPVFTEEMWR
LACCALQDAFSATLKPVKDLLGCFHGGTEGFSGEGCQVRVAAPSSSPSAE
AEYWRIRAMAQQVFMLDTQCSPKTPNNFDHAQSCQLIIELPHDEKPNGHA
KKSVSFREIVVSLLSHQVLLQNLYDILLEEFVKGPSPGEEKTVQVPDTKL
AGFLRYISMQNLAVIFDLLLDSYRTAREFDTSPGLKCLLKKVSGIGGAAN
LYRQSAMSFNIYFHALVCAVLTNQETITAEQVKKVLFEEEERSSDSSQQC
SSEDEDIFEETAQVSPPRGKEKRQWRARLPSLSVQPVSNADWVWLVKRLH
KLCMELCNHYIQMHLDLESSLEEPLTFKSDPFFILPSFQSESSTPSTGGF
SGKNTPSEDDRREHLSEPQSLRVGSGDMLMLPPSPKTEKKDPGRKKEWWE
SAGNKICTMAADKTISKLMTEYKKRRQPHNLPPFPKEVKVDKKGEPLGPR
GPDSPLLQRPQHLIDQGQMRHSFSAGPELLRQEKRPRSGSTGSSLSVSVR
DAEAQIQAWTNMVLTVLNQIQILPDQTFTALQPAVFPCISQLTCHVTDIR
VRQAVREWLGRVGRVYDIIT
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
