BIG4_ARATH
Brefeldin A-inhibited guanine nucleotide-exchange protein 4
MSTSQTLGGATRCGRIIGPSLDKIIKNAAWRKHTYLVSSCKSVLDKLESL
PDDFHDPSSVVSGLAASDADSVLQPFLLSLETAYSKVVEPSLDCAFKLFS
LSILRGEIQSSKQDSILFKLVNAVSKVGAIAEEPIQLAVLRVLLAAVRSP
CILIRGDCLLHVVKTCYNIYLGGLSGTTQICAKSVLAQMMLVIFTRSEED
SLDVSVKTIYVNELLTFTDKSVNEGSSVYFCQGFVNEVMAAGQGSPLPPP
DVIQILLQNPETETVMTPDSPSFRGYVANGEGDSETGDMSKVRQDAFLLF
KNLCKLSMRFSSKENNDDQIMVRGKTLSLELLKVIIDNGGSVWRTNESFI
NAVKQYLCLSLLKNSAVSIMSIFQLQCAIFMSLLSKLRSVLKAEIGIFFP
MIVLRVLENVLQPSYLQKMTVLNLLDKMSQDPQLMVDIFVNYDCDVESSN
ILERIVNGLLKTALGPPTGSSTTLSPAQDSTFRNDSVKCLVNLAKAMGNW
MDQQLKVNETVWPKGSQVYASMDSNASQISELEGTISDCDSQPDTSNPEA
YDASMLEQRRAYKIELQKGISLFNRKPSKGVEFLISTKKIGSSPEEVASF
LMKTAGLNGTVIGDYLGERDELPLKVMHAYVDSFNFEKKDFVEAIRFFLR
GFRLPGEAQKIDRIMEKFAEHYWKCNPGSFTSADTAYVLAYSVIMLNTDA
HNNMVKDKMTKADFVRNNRGIDDGKDLPEEYLGSLYDRVVKEEIRMNSDT
LAPQNKQVNGLNKLLGLDGILNLVSWMQPDEKPHGANGRLIRDIQEQFQA
KPEKSESVYHTVTDISILRFILEVSWGPMLAAFSVTIDQSDDRLATSLCL
QGFRYAVHVTAVMGMQTQRDAFVTSMAKFTNLHCAADMKQKNVDAVKAII
TIAIEDGNHLHGSWEHILTCLSRIEHLQLLGEVSPSEKRYVPTKKAEVDD
KKALGFPNLKKRGSFQNPSVMAVVRGGSYDSTSLVKSVPKLVTPEQIKSF
IANLNLLDQIGNFELNHVYANSQRLNSEAIVSFVKALCKVSMSELQSPTD
PRVFSLTKLVETAHYNMNRIRLVWSRIWNVLSDFFVSVGLSENLSVAIFV
MDSLRQLSMKFLEREELANYHFQHEFLRPFVVVMQKSSSAEIRELIVRCV
SQMVLSRVSNVKSGWKNVFTVFTTAALDERKNIVLLAFETIEKIVRDHFH
CIIETEITVYADCIRCLITFTNSKFEGDIGFNTIEFLRFCALKLEEGGLV
LNEKLKNNTISALKEDFSDTQSFTDLDEQVSYWIPLLTGLCKQVSDPRPA
IRKRSIEVLFHILMDHGHLFTRPFWTGIFSSIILPVFNNIRSKTDMLFEE
SVDSPSSASLDTEETTWDVETSTLALQLLVDLLVKFFRSVRSQLPSVVSI
IVGFIKSPFQGSTGSGISVLLHLADGLARSASEDEWREIFLALKEAASLT
FAGFMKVLRTMDDIEDVETLSGQSVNIGDLDDDSLHIMSYVVSRTKKHID
VLSQIVEVVSDLYRRNQFSLSASHVDILADIFSCIASHAQQLNTDTVLRR
KFKRACSVQNLTEPQLLNFENEAYKSYMMFLQDMVTCNPNVSKELDLESR
LVTECAKIVKIYLKCTDPQQQEQQQRKPVLWVLPMESDRVEEATARTSLL
VSSLEALCSLEAESLKKHVSSFFPLLVDLVRTEHCSPQVPYVLSNVLKSC
IGPILA
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
