CFTR_ORNAN
Cystic fibrosis transmembrane conductance regulator
MQRSPLERANLFSKLFFSWTKPILKKGYRQHLELSDIYQIPTADSADNLS
EKLEREWDRELASKKNPKLINALRRCFFWRFMFYGLLLYLGEVTKAVQPL
LLGRIIASYDPDNAHERSIAYYLGIGLCLLFIVRTLLLHPAVFGLHHIGM
QMRIALFSLIYKKTLKLSSRVLDKISTGQLVSLLSNNLNKFDEGLALAHF
VWIAPLQVMLLMGLLWDLLQASAFCGLAVLVVLVLFQAWLGHRMMKYRDR
RAGKINERLVITAEIIENIQSVKAYCWEEAMENMIESLRETELKLTRKAA
YMRYFNSSAFFFSGFFVVFLSVLPSMLTKGIVLRKIFTTISFCIVLRMAV
TRQFPWAVQMWYDSIGAIYKIQDFLQKEEYKTLEYNLTTTDVVMENVTAF
WDEGFGELLVKAKQNDSSRKVSSDDKNLIFSNISLLGPPVLKDISFKIEK
GQLLAVAGSTGAGKTSLLMMIMGELEPLEGKIKHSGRISFSPQFSWIMPG
TIKENIVFGVSFDEYRYRSVIKACQLEEEISKFAEKDNTVLGEGGITLSG
GQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTR
ILVTSKMEHLKKADKILILHEGSCYFYGAFSELQNLRPDFSSKLMGYDSF
DQFSAERRNSILTETLRRFSLDGDAAGSWNETKKQSFKQTGEFGERRKNS
ILNPLNSIRKFSLVQKAPLQMNCIDETLDEPPERKLSLVPDSEPGEAILP
RSNMLNPGPVLRARRRQSVLNLMTRPSIHQGSSLYKKGSASARKMSVAPQ
SNMSEMDIYSRRLSKDSGLEISEEINEEDLKECFIDDIESTTSVTTWNTY
LRYMTIHKKLIFVLMMCLVIFLIEVAASLVGLCLFKDGASRMNSTSNLNH
TSTLDWFAVIVTNTSTYYMFYIYVGVADTLLALGFLRGLPLVHSLISVSK
ILHQKMLHSVLQAPMSTFNTLKTGSILNRFSKDMAILDDLLPLTIFDFIQ
LLLIVIGAVTVVSALQPYIFLASVPVVIAFVLLRAYFLRTSQQLKQLESE
ARSPIFTHLITSLKGLWTLRAFGRQTYFEALFHKALNLHTANWFLYLSTL
RWFQMRIEMVFVIFFILVTFISILTTGDGEGKVGIVLTLAMNIMGTLQWA
VNASIDVDSLMRSVSRVFKFIDMPTEEHRPTHPAKNKDISGVLIIENQHV
KREKNWPSGGQMTVQDLTAKYLDGGPAILDNISFSISSGQRVGLLGRTGS
GKSTLLFAFLRLLNTEGDIRIDGISWDAVPVQQWRKAFGVIPQKVFIFSG
SFRKNLDPYGQWTDQELWKVAEEVGLKSVIEQFPGQLDFVLIDGGYVLSH
GHRQLMCLARSVLSKAKILLLDEPSAHLDPITYQVIRKTLKQAFTNCTVI
LSEHRIEAMLECQRFLVIEENKVRQYESIQKLLNEKSVFKQAISHSDKMK
LFPIHRRNSSKRLSRPKITALQEETEEEVQDTRL
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
