CFTR_OTOGA
Cystic fibrosis transmembrane conductance regulator
MQRSPLEKASVFSKLFFSWTRPILRKGYRQRLELSDIYQIPSADSADNLS
EKLEREWDRELASKKNPKLINALRRCFFWRFMFYGILLYLGEVTKAVQPL
LLGRIIASYDPDNKVERSIAIYLGIGLCLLFIVRTLLLHPAIFGLHHIGM
QMRIAMFSLIYKKILKLSSRVLDKISIGQLVSLLSNNLNKFDEGLALAHF
VWIAPLQVTLLMGLLWELLQASAFCGLGFLIVLALVQAGLGRMMMKYRDQ
RAGKINERLVITSEMIENIQSVKAYCWEEAMEKMIENLRQTELKLTRKAA
YVRYFNSSAFFFSGFFVVFLSVLPYALIKGIILRKIFTTISFCIVLRMAV
TRQFPWAVQTWYDSLGAINKIQDFLQKQEYKTLEYNLTTTEVVMENVTAF
WEEGIGELFEKAKQNNDNRKISNGDNSLFFSNLALLGAPVLKDINFKIER
GQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIMPG
TIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSG
GQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTR
ILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDFSSKLMGFDSF
DQFSAERRNSILTETLRRFSLEGDAAVSRNETKKQSFKQTGEIGEKRKNS
ILNPINSIRKFSVVQKTPLPMNGIDEEDSEEPVERRLSLVPDSEQGEAIL
PRSNVFNTGPTFQGRRRQSVLNLMTHSVNQGQNIHRKTAASTRKMSLAPQ
ANLTEMDIYSRRLSQESSLEISEEINEEYLKECFCDDVENIPAVTTWNTY
LRYLAVNKSLSLVLIWCLVIFLAEVAISLAVLLLLDKSPRYSKGNGTASG
NGSSAVIITSTSSYYLFYIYVGVADTLLALGFFRGLPLVHTLITVSKILH
HRMLHSVLRAPMSTLNMLKAGGILNRFSKDIAILDDLLPLTIFDFVQLLL
IVIGAVAVVSVLQPYIFLATVPVIAAFVILRGYFLHTSQQLKQLESEGRS
PIFTHLVTSLKGLWTLRAFGRQPYFETLFHKALNLHTANWFLYLSTLRWF
QMRIEMIFVVFFIAVTFISILTTGEGEGTVGIILTLAMNIMGTLQWAVNS
SIDVDSLMRSVSRVFKFIDMPTEEGRSTKSIKPSKDCQLSKVMIFENLHV
KKDDIWPSGGQMTVKDLTARYIDSGNAILENISFSISPGQRVGLLGRTGA
GKSTLLSAFLRLLNTEGDIQIDGVSWDSITLQQWRKAFGVIPQKVFIFSG
TFRKNLDPYEQWSDQEIWKVADEVGLRSVIEQFPGKLDFVLVDGGYVLSH
GHKQLMCLARSVLSKAKILLLDEPSAHLDPITYQIIRRTLKQAFADCTVI
LCEHRIEAMLECQRFLVIEENKVRQYDSIQKLLSEKSLFRQAISPSDRMK
LFPRRNSSKHKSRSPITALKEETEEEVQETRL
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
