DRTS_CRIFA
Bifunctional dihydrofolate reductase-thymidylate synthase
MSRAAAKFKIPMPVTKADFAFPSLRAFSIVVAADQQHGIGDGETIPWTVP
ETLAFFKDQTTLLRNKKPPTEKKRNAVVMGRKTWEVPLKFRPLKGRLNVV
LSCRRPVDDLLAQLPEEKRAAAAADVVINGGLKEALHLLARPPYCSSIET
AYCIGGARVYTEAMQSPCVEKLKEVYLTRVHTAPTCNRFYEFVRRRRARA
AVDLESTSGVKVSDAAAHLSYEIMKYVPHNAEERQYLELIDRIMKTGLVK
EDRTGVGTISLFGAQMFSLRDNQLPLLTTKRVFWRGVCEELIWFLRGETN
AHVLADKDIHIWDGNGSREFLDSRGLTENKEMDLGPVYGFQWRHFGADYK
GFDANYDEGVDQIKTIVETLKTNDRRLLVTAWNPCALHKMAVRPCHLLGQ
FYVNTQTKELSCMLYQRCCDMGLGVPFNIASYALLTILIAKATGLRPGEL
VHTLGTAHVYSNHVEALKEQLQRVPVAFPVLVFKKEREFLEDYESTDMEV
VDYVPYPPIKMEMAV
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
