ERN2_MOUSE
Serine/threonine-protein kinase/endoribonuclease IRE2
MARPVQRFQLWSPLGFLLQLVTLLGKLGPQVQSVRPESLLFVSTLDGSLH
ALNKQTGDLKWTVKDDPIIQGPMYVTEMAFLSDPADGSLYVLGTQKQQGL
MKLPFTIPELVHASPCRSSDGVFYTGRKQDAWFVVDPESGETQMTLTTEG
LSTPQLFIGRTQYTVSMHDLRTPALRWNTTYRRYSAPLLNGSPGKYMSHL
TSCGMGLLLTVDPGSGIVLWTQDLGVPVTGIYTWHQDGLHQLPHLTLARD
TLHFLVLRWGHIRLPASSYQDTATQFSSLDTQLLMTLYVGKEEAGFYVSK
ALVHAGVALVPRGLTLAPMDGPTTDEVTLQVSGEREGSPSTAVRYPSGSV
ALPSQWLLIGYHEPPPVLHTTMLRVHPIPGKVSAETRASEDLHAPPVFFE
LLNLRREDPELHPEEKASDSYPGLGSQDLLAATFTAILLGAWVLYLMRQQ
QQSPSAPAGPPDLSQDAQGQLSRDILQDQRRFQSPSEPAQPPHDPEAGQP
TVVGKISFNPKDVLGRGAGGTFVFRGQFEGRAVAVKRLLRECFGLVRREV
QLLQESDRHPNVLRYFCTEHGPQFHYIALELCQASLQEYVESPDLDRWGL
EPTTVLQQMMSGLAHLHSLHIVHRDLKPANILMAGPDSQGQGRVVISDFG
LCKKLPVGRCSFSLHSGIPGTEGWMAPELLQLPPDSPTSAVDIFSAGCVF
YYVLSGGSHPFGESLYRQANILSGDPCLAQLQEETHDKVVALDLVRAMLS
LLPQDRPSAGWVLAHPLFWSRAKELQFFQDVSDWLEKEPDQGPLVSALEA
GSYKVVREDWHKHISAPLQADLKRFRSYKGTSVRDLLRAMRNKKHHYREL
PAEVRQTLGQLPAGFIQYFTQRFPRLLL
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
