H7BZ57_HUMAN
RING-type E3 ubiquitin transferase
MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGV
QYKDYIQSERNLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNS
SVISRLHPCVDANNSRASEINLKKLQHLELMEDIVDLAKKVANDSFLIGG
LLRIGCKIENKILAMEEALNWIKYAGDVTILTKLGSIDNCWPMLSIFFTE
YKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNEEFSKERFDIA
IIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK
GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQI
EDLQGRTANKDPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINH
EMANGGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESE
KFSSSSPLTLPADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMA
LLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAISLLGIG
QPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE
KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAI
CCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTF
NDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPR
PILKQKCSSLEKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKN
EEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAMLLKELLSWKV
LSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE
PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLD
SIEGKQLDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDIF
TASWERLHVTLTESINSRCTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSK
PMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEFEA
LYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFS
AEYEFFPEETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKR
KKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVSDSSSAPAF
ENVKPKPVSANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPG
SEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTYLPFQRFDITQTP
PAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKNAA
AYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESN
RNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPY
NPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLK
RHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSN
ASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEE
SHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPD
MESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISEL
SFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDS
PGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGR
AARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLS
IDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVV
APSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHKGC
FKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
