| Visitors: | 312927 |
|---|---|
| # of TMPs: | 15327 |
| Server version: | v2.0.0 |
| Database release: | d.2.2 |
| Release date: | 22.07.2024 |
HTP viewer for HUWE1_MOUSE
HUWE1_MOUSE
E3 ubiquitin-protein ligase HUWE1
Evidence:
Exists
Reliability:
63.45
# of TM segments:
9
Cross ref(s)::
UniProt: HUWE1_MOUSE
MKVDRTKLKKTPTEAPADCRALIDKLKVCNDEQLLLELQQIKTWNIGKCE LYHWVDLLDRFDGILADAGQTVENMSWMLVCDRPEKEQLKMLLLAVLNFT ALLIEYSFSRHLYSSIEHLTTLLASSDMQVVLAVLNLLYVFSKRSNYITR LGSDKRTPLLTRLQHLAESWGGKENGFGLAECCRDLQMLKYPPSATTLHF EFYADPGAEVKIEKRTTSNTLHYIHIEQLDKISESPSEIMESLTKMYSIP KDKQMLLFTHIRLAHGFSNHRKRLQAVQARLHAISILVYSNALQESANSI LYNGLIEELVDVLQITDKQLMEIKAASLRTLTSIVHLERTPKLSSIIDCT GTASYHGFLPVLVRNCIQAMIDPSMDPYPHQFATALFSFLYHLASYDAGG EALVSCGMMEALLKVIKFLGDEQDQITFVTRAVRVVDLITNLDMAAFQSH SGLSIFIYRLEHEVDLCRKECPFVIKPKIQRPSTTQEGEEMETDMDGVQC IPQRAALLKSMLNFLKKAIQDPAFSDGIRHVMDGSLPTSLKHIISNAEYY GPSLFLLATEVVTVFVFQEPSLLSSLQDNGLTDVMLHALLIKDVPATREV LGSLPNVFSALCLNARGLQSFVQCQPFERLFKVLLSPDYLPAMRRRRSSD PLGDTASNLGSAVDELMRHQPTLKTDATTAIIKLLEEICNLGRDPKYICQ KPSIQKADGTATAPPPRSNHAAEEASSEDEEEEEVQAMQSFNSAQQNETE PNQQVVGTEERIPIPLMDYILNVMKFVESILSNNTTDDHCQEFVNQKGLL PLVTILGLPNLPIDFPTSAACQAVAGVCKSILTLSHEPKVLQEGLLQLDL ILSSLEPLHRPIESPGGSVLLRELACAGNVADATLSAQATPLLHALTAAH AYIMMFVHTCRVGQSEIRSISVNQWGSQLGLSVLSKLSQLYCSLVWESTV LLSLCTPNSLPSGCEFGQADMQKLVPKDEKAGTTQGGKRSDGEQDGTAGS MDASAQGLLEGIELDGDTLAPMETDEPSSSDSKGKSKITPAMAARIKQIK PLLSASSRLGRALAELFGLLVKLCVGSPVRQRRSHHAASTTTAPTPAARS TASALTKLLTKGLSWQPPPYTPTPRFRLTFFICSVGFTSPMLFDERKYPY HLMLQKFLCSGGHNALFETFNWALSMGGKVPVSEGLEHSDLPDGTGEFLD AWLMLVEKMVNPTTVLESPHSLPAKLPGGVQSFPQFSALRFLVVTQKAAF TCIKNLWNRKPLKVYGGRMAESMLAILCHILRGEPVIRERLSKEKEGSRG EEEAGQEEGGSRREPQVNQQQLQQLMDMGFTREHAMEALLNTSTMEQATE YLLTHPPPIIGGVVRDLSMSEEDQMMRAIAMSLGQDIPMDQRAESPEEVA CRKEEEERKAREKQEEEEAKCLEKFQDADPLEQDELHTFTDTMLPGCFHL LDELPDTVYRVCDLIMTAIKRNGADYRDMILKQVVNQVWEAADVLIKAAL PLTTSDTKTVSEWISQMATLPQASNLATRILLLTLLFEELKLPCAWVVES SGILNVLIKLLEVVQPCLQAAKEQKEVQTPKWITPVLLLIDFYEKTAISS KRRAQMTKYLQSNSNNWRWFDDRSGRWCSYSASNNSTIDSAWKSGETSVR FTAGRRRYTVQFTTMVQVNEETGNRRPVMLTLLRVPRLSKNSKSSNGQEL EKTLEESKETDIKHKENKGNDIPLALESTNTEKEASLDETKIGEILIQGL TEDMVTVLIRACVSMLGVPVDPDTLHATLRLCLRLTRDHKYAMMFAELKS TRMILNLTQSSGFNGFTPLVTLLLRHIIEDPCTLRHTMEKVVRSAATSGA GSTTSGVVSGSLGSREINYILRVLGPAACRNPDIFTEVANCCIRIALPAP RGSGTASDDEFENLRIKGPNAVQLVKTTPLKPSSLPVIPDTIKEVIYDML NALAAYHAPEEADKSDPKPGGTTQEVGQLLQDMGDDVYQQYRSLTRQSSD FDTQSGFSLNSQVFAADGAPAETSTTGTSQGEASTPEETREGKKDKEGDR TSEEGKQKSKGSKPLMPTSTILRLLAELVRSYVGIATLIANYSYTVGQSE LIKEDCSVLAFVLDHLLPHTQNAEDKDTPALARLFLASLAAAGSGTDAQV ALVNEVKAALGRALAMAESTEKHARLQAVMCIISTIMESCPSTSSFYSSA TAKTQHNGMNNIIRLFLKKGLVNDLARVPHSLDLSSPNMANTVNAALKPL ETLSRIVNQPSSLFGSKSASSKNKSEQDAQGASQDSSSHQQDPGEPGEAE VQEEDHDVTQTEVADGDIMDGEAETDSVVIAGQPEVLSSQEMQVENELED LIDELLERDGGSGNSTIIVSRSGEDESQEDVLMDEAPSNLSQASTLQANR EDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDE GEEGDEDDDDDGSEMELDEDYPDMNASPLVRFERFDREDDLIIEFDNMFS SATDIPPSPGNIPTTHPLMVRHADHSSLTLGSGSSTTRLTQGIGRSQRTL RQLTANTGHTIHVHYPGNRQPNPPLILQRLLGPSAAADILQLSSSLPLQS RGRARLLVGNDDVHIIARSDDELLDDFFHDQSTATSQAGTLSSIPTALTR WTEECKVLDAESMHDCVSVVKVPIVNHLEFLRDEELEERREKRRKQLAEE ETKIIDKGKEDKENRDQSAQCTVTKTNDSTEQNVSDGTPMPDSYPTTPSS TDAPTSESKETLGTLQPSQQQPALPPPPSLGEIPQELQSPAEEVANSTQL LMPIELEELGPTRPSGEAETTQMELSPAPTITSLSPERAEDSDALTAVSS QLEGSPMDTSSLASCTLEEAVGDTPAAGSSEQPTAGSSTPGDAPSVVAEV QGRPDVSRESNQPPEDSSPPASSESSSTRDSAVAISGADSRGILEEPLPS TSSEEEDPLAGISLPEGVDPSFLAALPDDIRREVLQNQLGIRPPTRSAPS SNSSAPAVVGNPGVTEVSPEFLAALPPAIQEEVLAQQRAEQQRRELAQNA SSDTPMDPVTFIQTLPSDLRRSVLEDMEDSVLAVMPPDIAAEAQALRREQ EARQRQLMHERLFGHSSTSALSAILRSPAFTSRLSGNRGVQYTRLAVQRG GTFQMGGSSSHNRPSGSNVDTLLRLRGRLLLDHEALSCLLVLLFVDEPKL NTSRLHRVLRNLCYHAQTRHWVIRSLLSILQRSSESELCIETPKLSTSEE RGKKSSKSCASSSHENRPLDLLHKMESKSSNQLSWLSVSMDAALGCRTNI FQIQRSGGRKHTEKHASSGSTVHIHPQAAPVVCRHVLDTLIQLAKVFPSH FTQQRTKETNCESDRERGSKQACSPCSSQSSSSGICTDFWDLLVKLDNMN VSRKGKNSVKSVPVSSGGEGETSPHSLEASPLGQLMNMLSHPVIRRSSLL TEKLLRLLSLISIALPENKVSEVQTNSSNSGSSTAATSNTSTTTTTTTTA TAPTPTPPAATTPVTSAPALVAATAISTITVAASTTVTTPTTATTTVSTS TTKGSKSPAKVGEGGSGIDFKMVSSGLTENQLQLSVEVLTSHSCSEEGLE DAANVLLQLSRGDSGTRDTVLKLLLNGARHLGYTLCKQIGTLLAELREYN LEQQRRAQCETLSPDGLPEEQPQTTKLKGKMQSRFDMAENVVIVASQKRP LGGRELQLPSMSMLTSKTSTQKFFLRVLQVIIQLRDDTRRANKKAKQTGR LGSSGLGSASSIQAAVRQLEAEADAIIQMVREGQRARRQQQAATSESSNQ SETSVRREESPMDVDQPSPSAQDTQSIVISDGTPQGEKEKEEKPPELPLL SEQLSLDELWDMLGECLKELEESHDQHAVLVLQPAVEAFFLVHATERESK PPVRDTRESQLAHIKDEPPPLSPAPLTPATPSSLDPFFSREPSSMHISSS LPPDTQKFLRFAETHRTVLNQILRQSTTHLADGPFAVLVDYIRVLDFDVK RKYFRQELERLDEGLRKEDMAVHVRRDHVFEDSYRELHRKSPEEMKNRLY IVFEGEEGQDAGGLLREWYMIISREMFNPMYALFRTSPGDRVTYTINPSS HCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKSVRYTDME SEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFGVCEVRDLKPNGANIL VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQEL ELLISGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFL QFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDL PAYESFEKLRHMLLLAIQECSEGFGLA
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix