| Visitors: | 312927 |
|---|---|
| # of TMPs: | 15327 |
| Server version: | v2.0.0 |
| Database release: | d.2.2 |
| Release date: | 22.07.2024 |
HTP viewer for HUWE1_RAT
HUWE1_RAT
E3 ubiquitin-protein ligase HUWE1
Evidence:
Exists
Reliability:
64.27
# of TM segments:
12
Cross ref(s)::
UniProt: HUWE1_RAT
MKVDRTKLKKTPTEAPADCRALIDKLKVCNDEQLLLELQQIKTWNIGKCE LYHWVDLLDRFDGILADAGQTVENMSWMLVCDRPEKEQLKMLLLAVLNFT ALLIEYSFSRHLYSSIEHLTTLLASSDMQVVLAVLNLLYVFSKRSNYITR LGSDKRTPLLTRLQHLAESWGGKENGFGLAECCRDLQMLKYPPSATTLHF EFYADPGAEVKIEKRTTSNTLHYIHIEQLDKISESPSEIMESLTKMYSIP KDKQMLLFTHIRLAHGFSNHRKRLQAVQARLHAISILVYSNALQESANSI LYNGLIEELVDVLQITDKQLMEIKAASLRTLTSIVHLERTPKLSSIIDCT GTASYHGFLPVLVRNCIQAMIDPSMDPYPHQFATALFSFLYHLASYDAGG EALVSCGMMEALLKVIKFLGDEQDQITFVTRAVRVVDLITNLDMAAFQSH SGLSIFIYRLEHEVDLCRKECPFVIKPKIQRPSTTQEGEEMETDMDVADV TMESSPGSSISMEHRLDVELRASSSNSSTSISGPGPGPGPGPGPGPGPGP GPGPGPGLGPSLGPGPGPGPRPGVQCIPQRAALLKSMLNFLKKAIQDPAF SDGIRHVMDGSLPTSLKHIISNAEYYGPSLFLLATEVVTVFVFQEPSLLS SLQDNGLTDVMLHALLIKDVPATREVLGSLPNVFSALCLNARGLQSFVQC QPFERLFKVLLSPDYLPAMRRRRSSDPLGDTASNLGSAVDELMRHQPTLK TDATTAIIKLLEEICNLGRDPKYICQKPSIQKADGTTSAPPPRSNHAAEE ASSEDEEEEEVQAMQSFNSAQQNETEPNQQVVGTEERIPIPLMDYILNVM KFVESILSNNTTDDHCQEFVNQKGLLPLVTILGLPNLPIDFPTSAACQAV AGVCKSILTLSHEPKVLQEGLLQLDLILSSLEPLHRPIESPGGSVLLREL ACAGNVADATLSAQATPLLHALTAAHAYIMMFVHTCRVGQSEIRSISVNQ WGSQLGLSVLSKLSQLYCSLVWESTVLLSLCTPNSLPSGCEFGQADMQKL VPKDEKAGTTQGGKRSDGEQDGTAGSMDASAQGLLEGIELDGDTLAPMET DEPSSSDSKGKSKITPAMAARIKQIKPLLSASSRLGRALAELFGLLVKLC VGSPVRQRRSHHAASTTTAPTPAARSTASALTKLLTKGLSWQPPPYTPTP RFRLTFFICSVGFTSPMLFDERKYPYHLMLQKFLCSGGHNALFETFNWAL SMGGKVPVSEGLEHSDLPDGTGEFLDAWLMLVEKMVNPTTVLESPHSLPA KLPGGVQSFPQFSALRFLVVTQKAAFTCIKNLWNRKPLKVYGGRMAESML AILCHILRGEPVIRERLSKEKEGSRGEEEAGQEEGGSRREPQVNQQQLQQ LMDMGFTREHAMEALLNTSTMEQATEYLLTHPPPIIGGVVRDLSMSEEDQ MMRAIAMSLGQDIPMDQRAESPEEVACRKEEEERKAREKQEEEEAKCLEK FQDADPLEQDELHTFTDTMLPGCFHLLDELPDTVYRVCDLIMTAIKRNGA DYRDMILKQVVNQVWEAADVLIKAALPLTTSDTKTVSEWISQMATLPQAS NLATRILLLTLLFEELKLPCAWVVESSGILNVLIKLLEVVQPCLQAAKEQ KEVQTPKWITPVLLLIDFYEKTAISSKRRAQMTKYLQSNSNNWRWFDDRS GRWCSYSASNNSTIDSAWKSGETSVRFTAGRRRYTVQFTTMVQVNEETGN RRPVMLTLLRVPRLSKNSKSSNGQELEKTLEESKETDIKRKENKGNDIPL ALESTNTEKDASLEETKIGEILIQGLTEDMVTVLIRACVSMLGVPVDPDT LHATLRLCLRLTRDHKYAMMFAELKSTRMILNLTQSSGFNGFTPLVTLLL RHIIEDPCTLRHTMEKVVRSAATSGAGSTTSGVVSGSLGSREINYILRVL GPAACRNPDIFTEVANCCIRIALPAPRGSGTASDDEFENLRIKGPNAVQL VKTTPLKPSSLPVIPDTIKEVIYDMLNALAAYHAPEEADKSDPKPGGMTQ EVGQLLQDMGDDVYQQYRSLTRQSSDFDTQSGFSLNSQVFAADGAPAETS TTGTSQGEGASTPEETREGKKDKEGDRTSEEGKQKGKGSKPLMPTSTILR LLAELVRSYVGIATLIANYSYTVGQSELIKEDCSVLAFVLDHLLPHTQNA EDKDTPALARLFLASLAAAGSGTDAQVALVNEVKAALGRALAMAESTEKH ARLQAVMCIISTIMESCPSTSSFYSSATAKTQHNGMNNIIRLFLKKGLVN DLARVPHSLDLSSPNMANTVNAALKPLETLSRIVNQPSSLFGSKSASSKS KSEQDAQGASQDSSSHQQDPGEPGEAEVQEEDHDVTQTEVADGDIMDGEA ETDSVVIAGQPEVLSSQEMQVENELEDLIDELLERDGGSGNSTIIVSRSG EDESQEDVLMDEAPSNLSQASTLQANREDSMNILDPEDEEEHTQEEDSSG SNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDYPD MNASPLVRFERFDREDDLIIEFDNMFSSATDIPPSPGNIPTTHPLMVRHA DHSSLTLGSGSSTTRLTQGIGRSQRTLRQLTANTGHTIHVHYPGNRQPNP PLILQRLLGPSAAADILQLSSSLPLQSRGRARLLVGNDDVHIIARSDDEL LDDFFHDQSTATSQAGTLSSIPTALTRWTEECKVLDAESMHDCVSVVKVP IVNHLEFLRDEELEERREKRRKQLAEEETKIIDKGKEDKENRDQSAQCTV SKTNDSTEQNVSDGTPMPDSYPTTPSSTDAPTSESKETLGTLQPSQQQPT LPPPPSLGEISQELQSPAEEVGNSTQLLMPIELEELGPTRPSGEAETTQM ELSPAPTITSLSPERAEDSDALTAVSSQLEGSPMDTSSLASCTLEEAVGD TPAAGSSEQPTAGSSTPGDAPSVGADVQGRPDVSRESTQPPEDSSPPASS ESSSTRDSAVAISGADSRGILEEPLPSTSSEEEDPLAGISLPEGVDPSFL AALPDDIRREVLQNQLGIRPPTRTAPSTNSSTPAVVGNPGVTEVSPEFLA ALPPAIQEEVLAQQRAEQQRRELAQNASSDTPMDPVTFIQTLPSDLRRSV LEDMEDSVLAVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSA ILRSPAFTSRLSGNRGVQYTRLAVQRGGTFQMGGSSSHNRPSGSNVDTLL RLRGRLLLDHEALSCLLVLLFVDEPKLNTSRLHRVLRNLCYHAQTRHWVI RSLLSILQRSSESELCIETPKLSTSEERGKKSSKSCASSSHENRPLDLLH KMESKSSNQLSWLSVSMDAALGCRTNIFQIQRSGGRKHTEKHASSGSTVH IHPQAAPVVCRHVLDTLIQLAKVFPSHFTQQRTKETNCESDRERGSKQAC SPCSSQSSSSGICTDFWDLLVKLDNMNVSRKGKNSVKSVPVSAGGEGETS LHSLEASPLGQLMNMLSHPVIRRSSLLTEKLLRLLSLISIALPENKVSEV QTNSSNSGSSTAATSNTSTTTTTTTATAPTPTPPAATTPVTSAPALVAAT AISTITVAASTTVTTPTTATTTVSTSTTKGNKSPAKVGEGGSSSVDFKMV SSGLTENQLQLSVEVLTSHSCSEEGLEDAANVLLQLSRGDSGTRDTVLKL LLNGARHLGYTLCKQIGTLLAELREYNLEQQRRAQCETLSPDGLPEEQPQ TTKLKGKMQSRFDMAENVVIVASQKRPLGGRELQLPSMSMLTSKTSTQKF FLRVLQVIIQLRDDTRRANKKAKQTGRLGSSGLGSASSIQAAVRQLEAEA DAIIQMVREGQRARRQQQAATSESSNQSETSVRREESPMDVDQPSPSAQD TQSIVVSDGTPQGEKEKEERPPELPLLSEQLSLDELWDMLGECLKELEES HDQHAVLVLQPAVEAFFLVHATERESKPPVRDTRESQLAHIKDEPPPLSP APLTPATPSSLDPFFSREPSSMHISSSLPPDTQKFLRFAETHRTVLNQIL RQSTTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRKEDMAVH VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIIS REMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYD NRLLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGY DLTFSTEVQEFGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIR KQLAAFLEGFYEIIPKRLISIFTEQELELLISGLPTIDIDDLKSNTEYHK YQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGI QKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEG FGLA
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix