ITPR3_HUMAN
Inositol 1,4,5-trisphosphate receptor type 3
Cross ref(s)::
UniProt:
ITPR3_HUMAN
PDBTM:
8ear,
7lhf,
8tk8,
8tkh,
8tki,
6dr0,
6dqv,
6dqz,
6dqn,
6dqs,
7t3r,
7t3t,
7t3p,
7t3u,
6dqj,
6dr2,
6dra,
6drc,
6uqk,
7t3q,
8tla,
8tl9,
8tkg,
8tkf,
8tkd,
8tke
TOPDB:
ITPR3_HUMAN
MSEMSSFLHIGDIVSLYAEGSVNGFISTLGLVDDRCVVEPAAGDLDNPPK
KFRDCLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQME
QKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRV
TLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQPLHASNYE
LSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEEVLKGGDVVRLFHAEQEK
FLTCDEYKGKLQVFLRTTLRQSATSATSSNALWEVEVVHHDPCRGGAGHW
NGLYRFKHLATGNYLAAEENPSYKGDASDPKAAGMGAQGRTGRRNAGEKI
KYCLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQS
TNVPIDIEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASS
MLASAVEKLNEGFISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVTK
PNRERQKLMREQNILKQVFGILKAPFREKGGEGPLVRLEELSDQKNAPYQ
HMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQSQIGYDILAEDTITALLH
NNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNHIAIPVTQE
LICKCVLDPKNSDILIRTELRPVKEMAQSHEYLSIEYSEEEVWLTWTDKN
NEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDE
ISQQLGVDLIFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVKFA
RLWTEIPTAITIKDYDSNLNASRDDKKNKFANTMEFVEDYLNNVVSEAVP
FANEEKNKLTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCVQGPPA
MLQAYEDPGGKNVRRSIQGVGHMMSTMVLSRKQSVFSAPSLSAGASAAEP
LDRSKFEENEDIVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVE
VFPMQDSGADGTAPAFDSTTANMNLDRIGEQAEAMFGVGKTSSMLEVDDE
GGRMFLRVLIHLTMHDYAPLVSGALQLLFKHFSQRQEAMHTFKQVQLLIS
AQDVENYKVIKSELDRLRTMVEKSELWVDKKGSGKGEEVEAGAAKDKKER
PTDEEGFLHPPGEKSSENYQIVKGILERLNKMCGVGEQMRKKQQRLLKNM
DAHKVMLDLLQIPYDKGDAKMMEILRYTHQFLQKFCAGNPGNQALLHKHL
HLFLTPGLLEAETMQHIFLNNYQLCSEISEPVLQHFVHLLATHGRHVQYL
DFLHTVIKAEGKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMK
AARDGVEDHSPLMYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVSVV
THEDCITEVKMAYVNFVNHCYVDTEVEMKEIYTSNHIWTLFENFTLDMAR
VCSKREKRVADPTLEKYVLSVVLDTINAFFSSPFSENSTSLQTHQTIVVQ
LLQSTTRLLECPWLQQQHKGSVEACIRTLAMVAKGRAILLPMDLDAHISS
MLSSGASCAAAAQRNASSYKATTRAFPRVTPTANQWDYKNIIEKLQDIIT
ALEERLKPLVQAELSVLVDVLHWPELLFLEGSEAYQRCESGGFLSKLIQH
TKDLMESEEKLCIKVLRTLQQMLLKKTKYGDRGNQLRKMLLQNYLQNRKS
TSRGDLPDPIGTGLDPDWSAIAATQCRLDKEGATKLVCDLITSTKNEKIF
QESIGLAIHLLDGGNTEIQKSFHNLMMSDKKSERFFKVLHDRMKRAQQET
KSTVAVNMNDLGSQPHEDREPVDPTTKGRVASFSIPGSSSRYSLGPSLRR
GHEVSERVQSSEMGTSVLIMQPILRFLQLLCENHNRDLQNFLRCQNNKTN
YNLVCETLQFLDIMCGSTTGGLGLLGLYINEDNVGLVIQTLETLTEYCQG
PCHENQTCIVTHESNGIDIITALILNDISPLCKYRMDLVLQLKDNASKLL
LALMESRHDSENAERILISLRPQELVDVIKKAYLQEEERENSEVSPREVG
HNIYILALQLSRHNKQLQHLLKPVKRIQEEEAEGISSMLSLNNKQLSQML
KSSAPAQEEEEDPLAYYENHTSQIEIVRQDRSMEQIVFPVPGICQFLTEE
TKHRLFTTTEQDEQGSKVSDFFDQSSFLHNEMEWQRKLRSMPLIYWFSRR
MTLWGSISFNLAVFINIIIAFFYPYMEGASTGVLDSPLISLLFWILICFS
IAALFTKRYSIRPLIVALILRSIYYLGIGPTLNILGALNLTNKIVFVVSF
VGNRGTFIRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFYSILLFDLIY
REETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFILEVD
RLPNNHSTASPLGMPHGAAAFVDTCSGDKMDCVSGLSVPEVLEEDRELDS
TERACDTLLMCIVTVMNHGLRNGGGVGDILRKPSKDESLFPARVVYDLLF
FFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDN
KTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLD
WFPRMRAMSLVSNEGEGEQNEIRILQDKLNSTMKLVSHLTAQLNELKEQM
TEQRKRRQRLGFVDVQNCISR
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Structure of
Related structures:
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
