L_VSIVA
RNA-directed RNA polymerase L
MEVHDFETDEFNDFNEDDYATREFLNPDERMTYLNHADYNLNSPLISDDI
DNLIRKFNSLPIPSMWDSKNWDGVLEMLTSCQANPISTSQMHKWMGSWLM
SDNHDASQGYSFLHEVDKEAEITFDVVETFIRGWGNKPIEYIKKERWTDS
FKILAYLCQKFLDLHKLTLILNAVSEVELLNLARTFKGKVRRSSHGTNIC
RIRVPSLGPTFISEGWAYFKKLDILMDPNFLLMVKDVIIGRMQTVLSMVC
RIDNLFSEQDIFSLLNIYRIGDKIVERQGNFSYDLIKMVEPICNLKLMKL
ARESRPLVPQFPHFENHIKTSVDEGAKIDRGIRFLHDQIMSVKTVDLTLV
IYGSFRHWGHPFIDYYTGLEKLHSQVTMKKDIDVSYAKALASDLARIVLF
QQFNDHKKWFVNGDLLPHDHPFKSHVKENTWPTAAQVQDFGDKWHELPLI
KCFEIPDLLDPSIIYSHKSHSMNRSEVLKHVRMNPNTPIPSKKVLQTMLD
TKATNWKEFLKEIDEKGLDDDDLIIGLKGKERELKLAGRFFSLMSWKFPE
YFVITEYLIKTHFVPMFKGLTMADDLTAVIKKMLDSSSGQGLKSYEAICI
ANHIDYEKWNNHQRKLSNGPVFRVMGQFLGYPSLIERTHEFFEKSLIYYN
GRPDLMRVHNNTLINSTSQPVCWQGQEGGLEGLRQKGWTILNLLVIQREA
KIRNTAVKVLAQGDNQVICTQYKTKKSRNVVELQGALNQMVSNNEKIMTA
IKIGTGKLGLLINDDETMQSADYLNYGKIPIFRGVIRGLETKRWSRVTCV
TNDQIPTCANIMSSVSTNALTVAHFAENPINAMIQYNYFGTFARLLLMMH
DPALRQSLYEVQDKIPGLHSSTFKYAMLYLDPSIGGVSGMSLSRFLIRAF
PDPVTESLSSWRFIHVHARSEHLKEMSAVFGNPEIAKFRITHIDKLVEDP
TSLNIAMGMSPANLLKTEVKKCLIESRQTIRNQVIKDATIYLYHEEDRLR
SFLWSINPLFPRFLSEFKSGTFLGVPDGLISLFQNSRTIRNSFKKKYHRE
LDDLIVRSEVSSLTHLGKLHLRRGSCKMWTCSATHADTLRYKSWGRTVIG
TTVPHPLEMLGPQHRKETPCAPCNTSGFNYVSVHCPDGIHDVFSSRGPLP
AYLGSKTSESTSILQPWERESKVPLIKRATRLRDAISWFVEPDSKLAMTI
LSNIHSLTGEEWTKRQHGFKRTGSALHRFSTSRMSHGGFASQSTAALTRL
MATTDTMRDLGDQNFDFLFQATLLYAQITTTVARDGWITSCTDHYHIACK
SCLRPIEEITLDSSMDYTPPDVSHVLKTWRNGEGSWGQEIKQIYPLEANW
KNLAPAEQSYQVGRCIGFLYGDLAYRKSTHAEDSSLFPLSIQGRIRGRGF
LKGLLDGLMRASCCQVIHRRSLAHLKRPANAVYGGLIYLIDKLSVSPPFL
SLTRSGPIRDELETIPHKIPTSYPTSNRDMGVIVRNYFKYQCRLIEKGKY
RSHYSQLWLFSDVLSIDFIGPFSISTTLLQILYKPFLSGKDKNELRELAN
LSSLLRSGEGWEDIHVKFFTKDILLCPEEIRHACKFGIPKDNNKDMSYPP
WGRESRGTITTIPVYYTTTPYPKMLEMPPRIQNPLLSGIRLGQLPTGAHY
KIRSILHGMGIHYRDFLSCGDGSGGMTAALLRENVHSRGIFNSLLELSGS
VMRGASPEPPSALETLGGDKSRCVNGETCWEYPSDLCDPRTWDYFLRLKA
GLGLQIDLIVMDMEVRDSSTSLKIETNVRNYVHRILDEQGVLIYKTYGTY
ICESEKNAVTILGPMFKTVDLVQTEFSSSQTSEVYMVCKGLKKLIDEPNP
DWSSINESWKNLYAFQSSEQEFARAKKVSTYFTLTGIPSQFIPDPFVNIE
TMLQIFGVPTGVSHAAALKSSDRPADLLTISLFYMAIISYYNINHIRVGP
IPPNPPSDGIAQNVGIAITGISFWLSLMEKDIPLYQQCLAVIQQSFPIRW
EAVSVKGGYKQKWSTRGDGLPKDTRISDSLAPIGNWIRSLELVRNQVRLN
PFNEILFNQLCRTVDNHLKWSNLRRNTGMIEWINRRISKEDRSILMLKSD
LHEENSWRD
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
