MDR1_TRIIM
ABC multidrug transporter MDR1
MASQPPQPPSGQPDTQYEEYQSEVITETTNRPTPAADVYEITPTNDVMDD
RYEHEHDDYESGAMYETVRTWSPQSRPELVRIASVFSRIDSHPDVAPTTE
DGGQLNRRDTLAGVKIGDPVLDPTKPEFDFYKWARMFTHVMEKEGIKRNR
TGVMFRNLTVLGSGSAVQYQDTFLSPFAAPFRPGELCGKGRNPEKVILHD
FNGAIREGELLMVLGRPGSGCSTFLKAICGELHGLQKKKESIIHYNGVSQ
HTFKKELRGEAVYSAEDEHHFPHLTVGQTLEFAAAARTPSKRVLGLSRKD
FSTHLARVMMSVFGLSHTYNTKVGDDYVRGVSGGERKRVSIAEIALSGAP
ICCWDNSTRGLDSATALEFTKALKIGSQVGGITQCLAIYQASQAIYDIFD
KVIVLYEGRQIFFGPTRIAKQYFEEMGWYCPPRQTTADFLTSVTNPKERI
AKEGYENRVPRTAVEFERYWKQSQNNKLLLANMDRFEAEYPPEEGHLEKL
RETHGQAQAKHTASKSPYRISVPMQVKLCTVRAYQRLWGDKSSTIATNIS
QIMMALIIGSLFFDTPQTTDGFFAKGSVIFFAILLNGLMSITEINGLCKA
TEPIVPNAQRPIVVKHVNFAFYHAYSEALAGIVADIPIKFLLALVFNIII
YFLGGLERSAAKFFIFFLFTFITILTMSAIFRTLAAATKTIPQALALAGV
MILALVIYTGFTLQPSYMHPWFKWILYINPIAYAYEALLVNEVHGNRYRC
ATPIPPYGSGKNFACAVAGAVPGEMSVSGDAWVESSYDYSYAHIWRNLGI
LLGFLAFFYFVYLMVSELNLSSASSAEFLVFRRGHLPKNFQGSKDEEAAA
GGVMHPNDPARLPPTNTNGAAGETAPGGSTVAVIPPQKDIFTWRNVTYDI
TIKGEPRRLLDNISGWVRPGTLTALMGVSGAGKTTLLDALAQRTTMGVIT
GDMLVNGRPLDSSFQRKTGYVQQQDLHLETTTVREALRFSADLRQPKSVS
RKEKYEYVEDVIKMLSMEDFSEAVVGNPGEGLNVEQRKLLTIGVELAAKP
QLLLFLDEPTSGLDSQSSWSIVTFLRKLADNGQAVLSTIHQPSGILFEQF
DRLLFLAKGGRTVYFGDIGKNSETLLNYFETHGAEPCGPSENPAEYMLNI
VGAGPSGKSNIDWPVVWKESEESRHVQQELDRIQSETSKRNEGHGQSAEK
EPGEFAMPFTSQLYCVTTRVFQQYWRTPSYIWGKLLLGLASALFIGFSFF
LQNSSMAGLQNSLFSIFMLTTIFSSLVQQIMPRFVTQRDLFEVRERPSRA
YSWKVFLLANIIVEIPYQILLGIIAWASLFYPTFGAHLSSERQGILLLYC
VQFFIFASTFAQMIIAGLPDAETAGGIATTMFGLMVTFNGVLQKPNALPG
FWRFMWRVSPITYTVGGLAATSLHSREVKCAQNELAIFDPPSGATCAQYL
QKLVEAGAPGKLYNPMSTSQCQYCPLSSGDQFLGGSEIHWSDRWRNFGIG
WAYIVFNIFATVALYYLIRVRKSSGRPNRIISVITYHLSQFGTYCRAFIT
GRKEKCPRKREQIGKIY
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
