| Visitors: | 312927 |
|---|---|
| # of TMPs: | 15327 |
| Server version: | v2.0.0 |
| Database release: | d.2.2 |
| Release date: | 22.07.2024 |
HTP viewer for R1AB_CVMJH
R1AB_CVMJH
Replicase polyprotein 1ab
Evidence:
Exists
Reliability:
62
# of TM segments:
22
Cross ref(s)::
UniProt: R1AB_CVMJH
MAKMGKYGLGFKWAPEFPWMLPNASEKLGNPERSEEDGFCPSAAQEPKVK GKTLVNHVRVDCSRLPALECCVQSAIIRDIFVDEDPQKVEASTMMALQFG SAVLVKPSKRLSVQAWAKLGVLPKTPAMGLFKRFCLCNTRECVCDAHVAF QLFTVQPDGVCLGNGRFIGWFVPVTAIPEYAKQWLQPWSILLRKGGNKGS VTSGHFRRAVTMPVYDFNVEDACEEVHLNPRGKYSCKAYALLRGYRGVKP ILFVDQYGCDYTGCLAKGLEDYGDLTLSEMKELSPVWRDSLDNEVVVAWH VDRDPRAVMRLQTLATVRSIEYVGQPIEDMVDGDVVMREPAHLLAPNAIV KRLPRLVETMLYTDSSVTEFCYKTKLCDCGFITQFGYVDCCGDTCGFRGW VPGNMMDGFPCPGCCKSYMPWELEAQSSGVIPEGGVLFTQSTDTVNRESF KLYGHAVVPFGGAAYWSPYPGMWLPVIWSSVKSYSYLTYTGVVGCKAIVQ ETDAICRFLYMDYVQHKCGNLEQRAILGLDDVYHRQLLVNRGDYSLLLEN VDLFVKRRAEFACKFATCGDGLVPLLLDGLVPRSYYLIKSGQAFTSLMVN FSREVVDMCMDMALLFMHDVKVATKYVKKVTGKVAVRFKALGIAVVRKIT EWFDLAVDTAASAAGWLCYQLVNGLFAVANGVITFIQEVPELVKNFVDKF KTFFKVLIDSMSVSILSGLTVVKTASNRVCLAGSKVYEVVQKSLPAYIMP VGCSEATCLVGEIEPAVFEDDVVDVVKAPLTYQGCCKPPSSFEKICIVDK LYMAKCGDQFYPVVVDNDTVGVLDQCWRFPCAGKKVVFNDKPKVKEVPST RKIKIIFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPC KEHGVIGTKVCALLERLVDDYVYLFDEGGEEVIASRMYCSFSAPDEDCVA TDVVYADENQDDDADDPVVLVADTQEEDGVAREQVDSADSEICVAHTGGQ EMTEPDVVGSQTPIASAEETEVGEACDREGIAEVKATVCADALDACPDQV EAFDIEKVEDSILSELQTELNAPADKTYEDVLAFDAIYSETLSAFYAVPS DETHFKVCGFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKA GYDQCFVDKLVKSAPKSIILPQGGYVADFAYFFLSQCSFKVHANWRCLKC GMELKLQGLDAVFFYGDVVSHMCKCGNSMTLLSADIPYTFDFGVRDDKFC AFYTPRKVFRAACAVDVNDCHSMAVVDGKQIDGKVVTKFNGDKFDFMVGH GMTFSMSPFEIAQLYGSCITPNVCFVKGDVIKVLRRVGAEVIVNPANGRM AHGAGVAGAIAKAAGKAFINETADMVKAQGVCQVGGCYESTGGKLCKKVL NIVGPDARGHGNECYSLLERAYQHINKCDNVVTTLISAGIFSVPTDVSLT YLLGVVTKNVILVSNNQDDFDVIEKCQVTSVAGTKALSFQLAKNLCRDVK FVTNACSSLFSESSFVSSYDVLQEVEALRHDIQLDDDARVFVQANMDCLP TDWRLVNKFDSVDGVRTIKYFECPGEVFVSSQGKKFGYVQNGSFKEASVS QIRALLANKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVR CSAIHKGKVFFQYSGLSAADLAAVKDAFGFDEPQLLQYYSMLGMCKWPVV VCGNYFAFKQSNNNCYINVACLMLQHLSLKFPKWQWRRPGNEFRSGKPLR FVSLVLAKGSFKFNEPSDSTDFIRVELREADLSGATCDLEFICKCGVKQE QRKGVDAVMHFGTLDKSGLVKGYNIACTCGDKLVHCTQFNVPFLICSNTP EGKKLPDDVVAANIFTGGSVGHYTHVKCKPKYQLYDACNVSKVSEAKGNF TDCLYLKNLKQTFSSVLTTYYLDDVKCVAYKPDLSQYYCESGKYYTKPII KAQFRTFEKVEGVYTNFKLVGHDIAEKLNAKLGFDCNSPFMEYKITEWPT ATGDVVLASDDLYVSRYSGGCVTFGKPVIWRGHEEASLKSLTYFNRPSVV CENKFNVLPVDVSEPTDRRPVPSAVLVTGAASGADASAISTEPGTAKEQK ACASDSVEDQIVMEAQKKSSVTTVAVKEVKLNGVKKPVKWNCSVVVNDPT SETKVVKSLSIVDVYDMFLTGCRYVVWTANELSRLINSPTVREYVKWGMS KLIIPANLLLLRDEKQEFVAPKVVKAKAIACYGAVKWFLLYCFSWIKFNT DNKVIYTTEVASKLTFKLCCLAFKNALQTFNWSVVSRGFFLVATVFLLWF NFLYANVILSDFYLPNIGPLPMFVGQIVAWVKTTFGVLTICDFYQVTDLG YRSSFCNGSMVCELCFSGFDMLDNYESINVVQHVVDRRVSFDYISLFKLV VELVIGYSLYTVCFYPLFVLVGMQLLTTWLPEFFMLGTMHWSARLFVFVA NMLPAFTLLRFYIVVTAMYKVYCLCRHVMYGCSKPGCLFCYKRNRSVRVK CSTVVGGSLRYYDVMANGGTGFCTKHQWNCLNCNSWKPGNTFITHEAAAD LSKELKRPVNPTDSAYYSVIEVKQVGCSMRLFYERDGQRVYDDVSASLFV DMNGLLHSKVKGVPETHVVVVENEADKAGFLNAAVFYAQSLYRPMLMVEK KLITTANTGLSVSRTMFDLYVYSLLRHLDVDRKSLTSFVNAAHNSLKEGV QLEQVMDTFVGCARRKCAIDSDVETKSITKSVMAAVNAGVEVTDESCNNL VPTYVKSDTIVAADLGVLIQNNAKHVQSNVAKAANVACIWSVDAFNQLSA DLQHRLRKACVKTGLKIKLTYNKQEANVPILTTPFSLKGGAVFSRVLQWL FVANLICFIVLWALMPTYAVHKSDMQLPLYASFKVIDNGVLRDVSVTDAC FANKFNQFDQWYESTFGLVYYRNSKACPVVVAVIDQDIGHTLFNVPTKVL RYGFHVLHFITHAFATDRVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHA DGTPHPYCYTEGVMHNASLYSSLVPHVRYNLASSNGYIRFPEVVSEGIVR VVRTRSMTYCRVGLCEEAEEGICFNFNSSWVLNNPYYRAMPGTFCGRNAF DLIHQVLGGLVQPIDFFALTASSVAGAILAIIVVLAFYYLIKLKRAFGDY TSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYFYTTLYFPSEISVVM HLQWLVMYGAIMPLWFCITYVAVVVSNHALWLFSYCRKIGTDVRSDGTFE EMALTTFMITKESYCKLKNSVSDVAFNRYLSLYNKYRYFSGKMDTATYRE AACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVE PCVVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSS DFCVMSDRMSLTVMSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTV LAAYNGRPQGAFHVVMRSSHTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQ LELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVAWLYAAILN RCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLVLDALASMTGVTVEQVLA AIKRLHSGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVIKGTC CWILASTFLFCSIISAFVKWTMFMYVTTHMLGVTLCALCFVIFAMLLIKH KHLYLTMYIMPVLCTLFYTNYLVVGYKQSFRGLAYAWLSYFVPAVDYTYM DEVLYGVVLLVAMVFVTMRSINHDVFSTMFLVGRLVSLVSMWYFGANLEE EVLLFLTSLFGTYTWTTMLSLATAKVIAKWLAVNVLYFTDIPQIKLVLLS YLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISVQELRYMNANGLRPPR NSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIA SNSKLWQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLAS IEEVSDDYVRDNTVLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQ QIKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKV VSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPPLTSNTLTIIVP DKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDVNSTWPLVIS ANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNCNIPTQCYYNTTGTGK IVYAILSDCDGLKYTKIVKEDGNCVVLELDPPCKFSVQDVKGLKIKYLYF VKGCNTLARGWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTY LDYIQQGGVPVTNCVKMLCDHAGTGMAITIKPEATTNQDSYGGASVCIYC RSRVEHPDVDGLCKLRGKFVQVPLGIKDPVSYVLTHDVCQVCGFWRDGSC SCVGTGSQFQSKDTNFLNRVRGTSVNARLVPCASGLDTDVQLRAFDICNA NRAGIGLYYKVNCFRFQRVDEEGNKLDKFFVVKRTNLEVYNKEKECYELT KDCGVVAEHEFFTFDVEGSRVPHIVRKDLSKFTMLDLCYALRHFDRNDCS TLKEILLTYAECDESYFQKKDWYDFVENPDIINVYKKLGPIFNRALLNTA NFADTLVEAGLVGVLTLDNQDLYGQWYDFGDFVKTVPCCGVAVADSYYSY MMPMLTMCHALDSELFVNGTYREFDLVQYDFTDFKLELFNKYFKHWSMTY HPNTSECEDDRCIIHCANFNILFSMVLPKTCFGPLVRQIFVDGVPFVVSI GYHYKELGVVMNMDVDTHRYRLSLKDLLLYAADPALHVASASALLDLRTC CFSVAAITSGVKFQTVKPGNFNQDFYEFILSKGLLKEGSSVDLKHFFFTQ DGNAAITDYNYYKYNLPTMVDIKQLLFVVEVVNKYFEIYEGGCIPATQVI VNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNL KYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKF YGGWDDMLRRLIKDVDSPVLMGWDYPKCDRAMPNILRIVSSLVLARKHDS CCSHTDRFYRLANECAQVLGEIVMCGGCYYVKPGGTSSGDATTAFANSVF NICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAFVSE YYEFLNKHFSMIILSDDGVVCYNSEFASKGYIANISDFQQVLYYQNNVFM SEAKCWVETDIEKGPHEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFV DDLLKTDSVLLIERFVSLAIDAYPLVYHENPEYQNVFRVYLEYIKKLYND LGNQILDSISVILSTCDGQKFTDETFYKNMYLRSAVMQSVGACVVCSSQT SLRCGSCIRKPLLCCKCAYDHVMSTDHKYVLSVSPYVCNSPGCDVNDVTK LYLGGMSYYCEAHKPQYSFKLVMNGMVFGLYKQSCTGSPYIEDFNKIASC KWTEVDDYVLANECTERLKLFAAETQKATEEAFKQCYASATIREIVSDRE LILSWEIGKVRPPLNKNYVFTGYHFTNNGKTVLGEYVFDKSELTNGVYYR ATTTYKLSVGDVFILTSHAVSSLSAPTLVPQENYTSVRFASAYSVPETFQ NNVPNYQHIGIKRYCTVQGPPGTGKSHLAIGHAVYYCTARVVYTAASHAA VDALCEKAHKFLNINDCARIVPAKLRVDCYDKFNVNDTTRKYVFTTINAL PELVTDIIVVDEVSMLTNYELSVINSRVRAKHYVYIGDPAQLPAPRVLLN KGTLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYNNKLKA KNDNSAMCFKVYYKGQTTHESSSAVNMQQIHLISKLLKANPSWSNAVFIS PYNSQNYVAKRVLGLQTQTADSAQGSAYDFVIYSQTAQTAHSVNVNRFNV AITRAKKGILCVMSSMQLIGVFNFTTLTLDKINNPRLQCTTNLFKDCSKS YVGIPPCAFLLAVDDKYKVSGNLAVCLNVADSAVTYSRLISLMGFKLDLT LDGYCKLFITRDEAIKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGI DFVVEATGMFAERDGYVFKKAAARAPPGEQFKHLVPLMSRGQKWDVVRIR IVQMLSDHLVDLADSVVLVTWAASFELTCLRYFAKVGKEVVCSVCNKRAT CFNSRTGYYGCWRHSYSCDYLYNPLIVDIQQWGYTGSLTSNHDPICSVHK GAHVASSDAIMTRCLAVHDCFCKSVNWNLEYPIISNEVSVNTSCRLLQRV MFRAAMLCNRYDVCYDIGNPKGLACVKGYDFKFYDASPVVKSVKQFVYKY EAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLSKLNLPGCNGGSLY VNKHAFHTNPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPLRS ATCITRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLW NTFTRLQSLENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVF KNNTPFPTNVAVELFAERSIRPHPELKLFRSSNIHVCWNHVLWDYAKDSV FCSSTYKVCKYTDLQCIESLNVLFDGRDNGALEAFKKCRNGVYINTTKIK SLSMIKGPQRADLNGVVVEKVGDSDVEFWFAMRRDGDDVIFSRTGSLEPS HYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRFLSSFSPRSEMEKDFMD LDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRPKKSNLVI QEFVPYDSSIHSYFITDENSGSSESVCTVIDLLLDDFVDIVKSLNLKCVS KVVNVNVDFKDFQFMLWCNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLE SPMERVNLWNYGKPITLPTGCMMNVAKYTQLCQYLSTTTLAVPANMRVLH LGAGSDKGVAPGSAVLRQWLPSGSILVDNDMNPFVSDSVASYYGNCITLP FDCQWDLIISDMYDPLTKNIGEYNVSKDGFFTYLCHLIRDKLALGGSVAI KITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWLNRTRNEI DGKTMHANYLFWRNSTMWNGGAYSLFDMTKFPLKAAGTAVVSLKPDQIND LVLSLIEKGKLLVRDTRKEVFVGDSLVNVK
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix