| Visitors: | 312927 |
|---|---|
| # of TMPs: | 15327 |
| Server version: | v2.0.0 |
| Database release: | d.2.2 |
| Release date: | 22.07.2024 |
HTP viewer for R1A_BC133
R1A_BC133
Replicase polyprotein 1a
Evidence:
TOPDOM
Reliability:
88.3
# of TM segments:
10
Cross ref(s)::
UniProt: R1A_BC133
MLSKAGVTTQGARGKYRAELYNEKRSDHVACTVPLCDTEDMASKLTPWFE DGETAFNQVSSILKEKGKILFVPMHMQRAMKFLPGPRVYLVERLTGGMLS KHFLVNQLAYKDHVGAAMMRTTLNVKPLGMFFPYDSSLETGEHTFLLRKN GLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQNLLKKLIGGDCIPV DQYMCGKNGKPIADYAKIVAKEGLTTLADIEVDVKSRMDSDRFIVLNKKL YRVVWNVTRRNVPYSKQTAFTVVSVIQCDDKESVPEHTFTIGSQILMVSP LKATNNKNFNLKQRLLHTFYGKEAVQQPGYIYHSAYVDCNACGRGTWCTG NAIQGFACDCGANYSANDVDLQSSGLVPKNALFLANCPCANNGACSHNAA QVYSILDGKACVEVGGKSFTLTFGGVVYAYMGCCDGTMYFVPRAKSCVSR IGDAIFTGCTGTWDKVVETANLFLEKAQHSLNFCQQFALTEVVLAILSGT TSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDYIRDAINIGANGVCNA TINAPFIAFTGLGESFKKVAAIPWKICSNLKSALDYYCSNIMFRVFPYDI PCDVNDFVELLLDCGKLTVATSYFVLRYLDEKFDTVLGTVSNACQTALSS FLNACVAASRATAGFISDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQ QVLDIMSKAMKLLHTNVSWAGTKLSAIIYEGREALLFNSGTYFCLSTKAK TLQDQMNLVLPGDYNKKTLGILDPVPNADTIDVTANSTVVDVVHGQLEPT NEHGPSMIVGNYVLVSDKLFVRTDDEEFYPLCINGKVVSTLFRLKGGMPS KKVTFGDVNTVEVTAYRSVSITYDIHPVLDALLSSSKLATFTVEKDLLVE DFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYVYNQDGDCAWSSN MTFSINPVEDVEEVEEFIEDDYLSDELPIADDEEAWTRAVEEVMPLDDIL VAEIELEEDLPLETALESVEAEVGESISDELCVVETAKAQEPSVESTDST PSTSTVVSENDLSVKPMSRVAETGDVLEVETAVVGGPVSDVTASVVTNDI VSVEQAQQCGVSSLPIQDEASENQVHQVPDLQCTSETKVEIVQPRQDLRP RRLRKSKVDLSKYKHTVINNSVTLVLGDAIQIASLLPKCVLVNAANRHLK HGGGIAGAINKASGGDVQEESDEYISNSGPLHVGDSVLLKGYGLADAILR VVGPDARNNEDAALLKRCYKTFNKHTIVVTPLISSGIFSVDPKVSFEYLL ANVTTTTYVVVNNEDIYNTLATPSKPDGLVYSFEGWRGTVRTAKNYGFTC FICTEYSANVKFLRTKGVDTTKKIQTVDGVSYYLYSARDALTDVIAAANG CPGICAMPFGYVTHGLDLAQSGNYVRQVKVPYVCLLASKEQIPIMNSDVA IQTPETAFINNVTSNGGYHSWHLVSGDLIVKDVCYKKLLHWSGQTICYAD NKFYVVKNDVALPFSDLEACRAYLTSRAAQQVNIEVLVTIDGVNFRTVIL NDATTFRKQLGATFYKGVDISDALPTVKMGGESLFVADNLSESEEVVLKE YYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATIMMI DMLHDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLL HTLLAKAELTVSAKMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQS VFNETCVCGSVKHRQLVEHSTPWLLVSGLNEVKVSTSTDPVYRAFNVFQG VETSVGHYVHVRVKDGLFYKYDSGSLTKTSDMKCKMTSVWYPKVRYTADC NVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKPTIKYSPATILPGSVYS NSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNEDGDVLL SEFNNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPI VLDNKYTVLQDNTSQLIEPNVPVVEDVSITTRKLIEVKCKGLNKPFVKGN FSFVNDPNGVTVVDTLGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVE SGDLQIVANGGSVTRRARVLLGASSLFASFAKITVTATTAACKTAGRSFC KFVVNYGVLQNMFLFLKMLFFLPFNYLWPKKQPTVDVGVSGLRTAGVVTT NIVKQCGTAAYYMLLGKFKRVDWKATLRLFLLLCTTILLLSSIYHLVIFN QVLSSDVMLEDATGILAMYKEVRSYLGIRTLCDGLAVEYRNTSFDVVDFC SNRSVLCQWCLIGQDSLTRYSALQMLQTHITSYVLNIDWIWFALEFFLAY VLYTSSFNVLLLVVTAQYFFAYTSAFVNWRAYNYIVSGLFFLVTHIPLHG LVRVYNFLACLWFLRKFYSHVINGCKDTACLLCYKRNRLTRVEASTIVCG TKRTFYIAANGGTSYCCKHNWNCVECDTAGVGNTFICTEVANDLTTTLRR LIKPTDQSHYYVDSVVVKDAVVELHYNRDGSSCYERYPLCYFTNLEKLKF KEVCKTPTGIPEHNFLIYDTNDRGQENLARSACVYYSQVLCKPMLLVDVN LVTTVGDSREIAIKMLDSFINSFISLFSVSRDKLEKLINTARDCVRRGDD FQTVLKTFTDAARGHAGVESDVETTMVVDALQYAHKNDIQLTTECYNNYV PGYIKPDSINTLDLGCLIDLKAASVNQTSMRNANGACVWNSGDYMKLSDS FKRQIRIACRKCNIPFRLTTSKLRAADNILSVKFSATKIVGGAPSWLLRV RDLTVKGYCILTLFVFTVAVLSWFCLPSYSIATVNFNDDRILTYKVIENG IVRDIAPNDACFANKYGHFSKWFNENHGGVYRNSVDCPITIAVIAGVAGA RVANVPATLAWVGRQIVLFVSRVFANTNVCFTPTNEIPYDTFSDSGCVLS SECTLFRDAEGNLNPFCYDPTVLPGASSYADMKPHVRYDMYDSDMYIKFP EVIFESTLRITKTLATQYCRFGSCEESAAGVCISTNGSWALYNQNYSTRP GIYCGDDYFDIVRRLAVSLFQPVTYFQLSTSLAMGLVLCVFLTAAFYYIN KVKRALADYTQCAVVAVVAALLNSLCLCFIVANPLLVAPYTAMYYYATFY LTGEPAFIMHISWYVMFGTVVPIWMLASYTVGVMLRHLFWVLAYFSKKHV DVFTDGKLNCSFQDAASNIFVIGKDTYVALRNAITQDSFVRYLSLFNKYK YYSGAMDTASYREACAAHLCKALQTYSETGSDILYQPPNCSVTSSVLQSG LVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDP NYDALLISKTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTP AYTFSTVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVG YTENGGVLNFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTDKY CTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVGTQSID MLAHRTGVSVEQMLAAIQSLHAGFQGKTILGQSTLEDEFTPDDVNMQVMG VVMQSGVKRISYGFMHWLMSTLVLAYVSVMQLTKFTMWTYLFETIPTQMT PLLFGFMACVMFTVKHKHTFLSLFLLPVALCLTYANIVYEPQTLVSSTLI AVANWLTPTSVYMRTTHLDFGLYISLSFVLAIIVRRLYRPSMSNLALALC SGVMWFYTYVIGDHSSPITYLMFITTLTSDYTITVFATVNLAKFISGLVF LYAPHLGFILPEVKLVLLIYLCLGYMCTMYFGVFSLLNLKLRVPLGVYDY SVSTQEFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQSKLT DLKCTSVVLLTVLQQLHLESNSKAWSYCVKLHNEILAAVDPTEAFERFVC LFATLMSFSANVDLDALANDLFENSSVLQATLTEFSHLATYAELETAQSS YQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAVARKLERMAEQAMTSM YKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSIV PLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDVTVINNVDNEVVKPT DVVETNESLTWPLVIECSRASSSAVKLQNNEIHPKGLKTMVVTAGIDQVN CSSSAVAYYEPVQGHRMVMGLLSENAHLKWAKVEGKDGFINIELQPPCKF LIAGPKGPEIRYLYFVKNLNNLHRGQLLGHIAATVRLQAGANTEFASNST VLTLVAFAVDPAKAYLDYVGSGGTPLSNYVKMLAPKTGTGVAISVKPEAT ADQETYGGASVCLYCRAHIEHPDVSGVCKYKTRFVQIPAHVRDPVGFLLK NVPCNVCQYWVGYGCNCDALRNNTVPQSKDTNFLNESGVLV
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
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Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix