| Visitors: | 312927 |
|---|---|
| # of TMPs: | 15327 |
| Server version: | v2.0.0 |
| Database release: | d.2.2 |
| Release date: | 22.07.2024 |
HTP viewer for R1A_BC279
R1A_BC279
Replicase polyprotein 1a
Evidence:
TOPDOM
Reliability:
89.09
# of TM segments:
8
Cross ref(s)::
UniProt: R1A_BC279
MESLALGVSEKTHVQLSLPVLQVRDVLVRGFGDSVEEALAEAREHLKNGT CGLVELEKGVLPQLEQPYVFIKRSDAQGTNHGYKVVELVAELDGIQYGRS GTTLGVLVPHVGETPVAYRNVLLRKNGNKGAGGHSYGIDLKSYDLGVELG TDPIEDYEQNWNTKHGGGVLRELIRELNGGAFTRYVDNNFCGPDGYPLEC IKDLLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVWFTERSEKSYE RQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLV CEGPTTCGYLPANAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKG GRTKCFGGCVFAYVGCYNKRAYWVPRASANIGASHTGITGDNVETLNEDL MEILNRDRVNINIVGDFHLNEEVAIILASFSASTCAFVDTVKGLDYKTFK DIVESCGNFKVTRGRAKKGAWNIGQEKSILTPLYGFPSQAAGVIRSIFTR ALDTANHSIPDLQRAAITILDGISEQSLRLIDAMVYTSDLLTNSVIVMAY VTGGLVQQITQWLSNMLGTTVDKLKPVFTWVEAKLSAGIEFLRDAWEILK FLVTGVFDIVKGQIQVASDNLKECVKAFLDVLNKALEMCIDQVIIAGAKL RTLNLGEVFIAQSKGLYRQCIRGKEQLQLLMPLRAPKEVTFFEGDSHDTV FTSEEVVLKNGELEALETPVDSFTNGAVIGTPVCVNGLMLLELKDKEQYC ALSPGLLATNNVFSLKGGAPVKGVTFGEDTVLEVQGYKNVKITFELDERV DKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCEEYEDEEEIPEETCEH EYGTEDDYKGLPLEFGASTEIQQVDEEEEEDWLEEAIAAKPEPEPLPEEP VNQFTGYLKLTDNVAIKCVDIVKEAQHAKPTVIVNAANVHLKHGGGVAGA LNKATNGAMQQESDDYIKKNGPLTVGGSCLLSGHNLAKKCMHVVGPNLNA GEDVQLLKAAYANFNSQDVLLAPLLSAGIFGAKPLQSLKMCVETVRTQVY FAVNDQDLYDHVVLGYLDSLKPKVETPTQENLELKEQPAVETLTQENLEL EELPVIEKPVDVKFKARIEEVNTSLEETKFLTSRLLLFADINGKLYQDSQ NMLRGEDMFFLEKDAPYIVGDVISSGDITCVIIPAKKAGGTTEMLAKALK KVPVSEYITTYPGQGCAGYTLEEAKTALRKCKSVFYVLPSKTPNDKEEIL GTVSWNLREMLAHAEETRKLMLICMDVKALMSTIHRRYKGIKVQEGIVDY GVRFFFYTSKEPVASIITKLNLLNEPLVTMPIGYVTHGLNLEEAARCMRS LKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFIETVSLAGMYRDWSYSG QRTELGVEFLKRGDKVVYHTVGSPIQFHLDGEVLLLDKLKSLLSLREVRT IKVFTTVDNTNLHTQIVDMSMTYGQQFGPTYLDGADVTKIKPHAKHEGKT FFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQIGGLTSI KWADNNCYLSSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALILAY SNRTVGELGDVRETMTHLLQHANLESAKRVLNVVCKTCGQKSTTLTGVEA VMYMGTLSYEELKTGVTIPCICGRDATQYLVQQESSFVMMSAPPSEYTLQ QGAFLCANEYTGSYQCGHYTHVTVKETLYRIDGAYLTKMSEYKGPVTDVF YKEISYTTTIKPVSYKLDGVIYTEIQPKLDEYYKKDNAYYTEQPIDLVPT QPLPNASFDNFKLTCSNTKFADDLNQMTGFKKPASRELSVTFFPDLNGDV VAIDYRHYSASFKKGAKLLHKPIIWHINQTTNKTTYKPNTWCLRCLWSTK PVETSNSFEVLEVEDTQGMDNLACESQTPTSEEVVENPTIQKEVIECDVK TIEVVGNVILKPSEEGVKVTQELGHEDLMAAYVEETSITIKKPNELSLAL GLRTLATHGAAAINSVPWSKILAYVKPFLGQAAVTTTNCIKRCVQRVFNN YMPYVITLLFQLCTFTRSTNSRIRASLPTTIAKNSVKSVAKLCLDVCINY VKSPKFSKLFTIAMWLLLLSICLGSLIYVTAAFGVLLSNLGIPSYCDGVR ESYVNSSNVTTMDFCEGSFLCSVCLNGLDSLDSYPALETIQVTISSYKLD LTSLGLAAEWFLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWF IISIVQMAPVSAMVRMYIFFAFCYYVWKSYVHIMDGCTSSTCMMCYKRNR ATRVECTTIVNGMKRSFYVYANGGRGFCKAHNWNCLNCDTFCAGSTFISD EVARDLSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAGQKTYERHP LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQ PILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAH SELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTG DSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKD YMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNAITTKISLKGGKIVS TWFKLMLKATLLCVLAALFCYIIMPVHSLSVHDGYTNEIIGYKAIQDGVT RDIMATDDCFANKHAGFDSWFSQRGGSYRNDKSCPVVAAIITREIGFIVP GLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAA ECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNT YLEGSVRVVTTFDAEYCRHGTCERSEAGVCLSTSGRWVLNNEHYRALPGV FCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKF RRAFGEYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFYLYLTFYFT NDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMF NGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYF SGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFR KMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNY EDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFV RIQPGQTFSVLACYNGSPSGVYQCAMRPNYTIKGSFLNGSCGSVGFNIDY DCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNV LAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLS AQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVT FQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLG IMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL ELADTSLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVWTLMNVITL VYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYP LLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVST QEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKC TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSV LLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQA VANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQAR SEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTA AKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD NSQNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDN ALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVT DTPRGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSAVL SFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMD QESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPATCANDPVGFTLKN TVCTVCGTWKGYGCSCDQLREPMMQSADASTFLNGFAV
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
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Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix