| Visitors: | 312927 |
|---|---|
| # of TMPs: | 15327 |
| Server version: | v2.0.0 |
| Database release: | d.2.2 |
| Release date: | 22.07.2024 |
HTP viewer for R1A_CVBM
R1A_CVBM
Replicase polyprotein 1a
Evidence:
TOPDOM
Reliability:
78.85
# of TM segments:
8
Cross ref(s)::
UniProt: R1A_CVBM
MSKINKYGLELHWAPEFPWMFEDAEEKLDNPSSSEVDIVCSTTAQKLETG GICPENHVMVDCRRLLKQECCVQSSLIREIVMNTRPYDLEVLLQDALQSR EAVLVTPPLGMSLEACYVRGCNPNGWTMGLFRRRSVCNTGRCAVNKHVAY QLYMIDPAGVCFGAGQFVGWVIPLAFMPVQSRKFIVPWVMYLRKCGEKGA YNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKKAYALIRGYRGVKPL LYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPFDVTVAWHV VRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYADDSIIL RQHNLVDIMSCFYMEADAVVNAFYGVDLKDCGFVMQFGYIDCEQDLCDFK GWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGGF GCKDSFTLYGQTVVYFGGCVYWSPARNIWIPILKSSVKSYDGLVYTGVVG CKAIVKETNLICKALYLDYVQHKCGNLHQRELLGVSDVWHKQLLLNRGVY KPLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQA FCDYAGKICHAVVSKSKELLDVSLDSLGAAIHYLNSKIVDLAQHFSDFGT SFVSKIVHFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYFVKNIPRYA SAVAQAFRSVAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERGL LHSSQLPLDVYDLTMPSQVQKTKQKPIYLKGSGSDFSLADSVVEVVTTSL TPCGYSEPPKVADKICIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPC AGRCVTFKEQPTVNEIASTPKTIKVFYELDKDFNTILNTACGVFEVDDTV DMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQKLEDNSLFLFDEAGE EVLAPKLYCAFTAPEDDDFLEESGVEEDDVEGEETDLTVTSAGEPCVASE QEESSEILEDTLDDGPCVETSDSQVEEDVQMSDFVDLESVIQDYENVCFE FYTTEPEFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWV LYKQQYSQLFVDTLVNKIPANIVVPQGGYVADFAYWFLTLCDWQCVAYWK CIKCDLALKLKGLDAMFFYGDVVSHVCKCGESMVLIDVDVPFTAHFALKD KLFCAFITKRSVYKAACVVDVNDSHSMAVVDGKQIDDHRITSITSDKFDF IIGHGMSFSMTTFEIAQLYGSCITPNVCFVKGDIIKVSKRVKAEVVVNPA NGHMAHGGGVAKAIAVAAGQQFVKETTDMVKSKGVCATGDCYVSTGGKLC KTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISAGIFSVPSD VSLTYLLGTAKKQVVLVSNNQEDFDLISKCQITAVEGTKKLAERLSFNVG RSIVYETDANKLILSNDVAFVSTFNVLQDVLSLRHDIALDDDARTFVQSN VDVVPEGWRVVNKFYQINGVRTVKYFECPGGIDICSQDKVFGYVQQGSFN KATVAQIKALFLDKVDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVN VTKHKCDINYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYNMLVNC SKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFR SGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICDFEIACK CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLIHCVRFDVPFL ICSNTPASVKLPKGVGSANIFKGDKVGHYVHVKCEQSYQLYDASNVKKVT DVTGNLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKY YTQRIIKAQFKTFEKVDGVYTNFKLIGHTVCDILNAKLGFDSSKEFVEYK VTEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLTYF NRPLLVDENKFDVLKVDDVDDGGDISESDAKEPKEINIIKLSGVKKPFKV EDSVIVNDDTSEIKYVKSLSIVDVYDMWLTGCRCVVRTANALSRAVNVPT IRKFIKFGMTLVSIPIDLLNLREIKPVFNVVKAVRNKISACFNFIKWLFV LLFGWIKISADNKVIYTTEVASKLTCKLVALAFKNAFLTFKWSVVARGAC IIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIAQWIKNTFSLVTI CDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQYEADRRAF VDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLH WSVRLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFC YKRNRSLRVKCSTIVGGMIRYYDAMANGGTGFCSKHQWNCIDCDSYKPGN TFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFYDRDGQRT YDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDADKANFLNAAVFYAQS LFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIA TAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGL ELTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIW SVDAFNQLSSDFQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFSLKGG AVFSYFVYVCFVLSLVCFIGLWCLMPTYTVHKSDFQLPVYASYKVLDNGV IRDVSVEDVCFANKFEQFDQWYESTFGLSYYSNSMACPIVVAVVDQDFGS TVFNVPTKVLRYGYHVLHFITHALSADGVQCYTPHSQISYSNFYASGCVL SSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRF PEVLREGLVRIVRTRSMPYCRVGLCEEADEGICFNFNGSWVLNNDYYRSL PGTFCGRDVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYL IKLKRAFGDYTSIVFVNVIVWCVNFMMLFVFQVYPTLSCVYAICYFYATL YFPSEISVIMHLQWLVMYGTIMPLWFCLLYISVVVSNHAFWVFSYCRQLG TSVRSDGTFEEMALTTFMITKDSYCKLKNSLSDVAFNRYLSLYNKYRYYS GKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSGIV KMVNPTSKVEPCIVSVTYGNMTLNGLWLGDKVYCPRHVICSASDMTNPDY TNLLCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFG VVKPGETFTVLAAYNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVVYVIMG DCVKFVYMHQLELSTGCHTGTDFNGDFYGPYKDAQVVQLPVQDYIQSVNF VAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQVKSDLVIDALASM TGVSLETLLAAIKHLKNGFQGRQIMGSCSFEDELTPSDVYQQLAGIKLQS KRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTNMLSITFCALCV ISLTMLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYY VPSVEYTYTDEVIYGMLLLIGMVFVTLRSINQYLFSFIMFVGRVISVVSL WYMGSNLEEEILLMLASLFGTYTWTTALSMAAAKVIAKWVAVNVLYFTDI PQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMPLGVYNYKISVQELRYM NANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLTDVKCANVVLL NCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPA AVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEA CSSGSANQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEA RINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLA ANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLHEISD DCNWPLVIIANRHNEVSATALQNNELMPAKLKTQVVNSGPDQTCNTPTQC YYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVVLELDPPCKFTVQDVK GLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCA FSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSY GGASVCIYCRARVEHPDVDGLCKLRGKFVQVPVGIKDPVSYVLTHDVCQV CGFWRDGSCSCVSTDTTVQSKDTNFLNGFGVRV
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix