| Visitors: | 312927 |
|---|---|
| # of TMPs: | 15327 |
| Server version: | v2.0.0 |
| Database release: | d.2.2 |
| Release date: | 22.07.2024 |
HTP viewer for R1A_CVHN5
R1A_CVHN5
Replicase polyprotein 1a
Evidence:
TOPDOM
Reliability:
86.83
# of TM segments:
10
Cross ref(s)::
UniProt: R1A_CVHN5
MIKTSKYGLGFKWAPEFRWLLPDAAEELASPMKSDEGGLCPSTGQAMESV GFVYDNHVKIDCRCILGQEWHVQSNLIRDIFVHEDLHVVEVLTKTAVKSG TAILIKSPLHSLGGFPKGYVMGLFRSYKTKRYVVHHLSMTTSTTNFGEDF FGWIVPFGFMPSYVHKWFQFCRLYIEESDLIISNFKFDDYDFSVEAAYAE VHAEPKGKYSQKAYALLRQYRGIKPVLFVDQYGCDYSGKLADCLQAYGHY SLQDMRQKQSVWLANCDFDIVVAWHVVRDSRFVMRLQTIATICGIKYVAQ PTEDVVDGDVVIREPVHLLSADAIVLKLPSLMKVMTHMDDFSIKSIYNVD LCDCGFVMQYGYVDCFNDNCDFYGWVSGNMMDGFSCPLCCTVYDSSEVKA QSSGVIPENPVLFTNSTDTVNPDSFNLYGYSVTPFGSCIYWSPRPGLWIP IIKSSVKSYDDLVYSGVVGCKSIVKETALITHALYLDYVQCKCGNLEQNH ILGVNNSWCRQLLLNRGDYNMLLKNIDLFVKRRADFACKFAVCGDGFVPF LLDGLIPRSYYLIQSGIFFTSLMSQFSQEVSDMCLKMCILFMDRVSVATF YIEHYVNRLVTQFKLLGTTLVNKMVNWFNTMLDASAPATGWLLYQLLNGF FVVSQANLNFVALIPDYAKILVNKFYTFFKLLLECVTVDVLKDMPVLKTI NGLVCIVGNKFYNVSTGLIPGFVLPCNAQEQQIYFFEGVAESVIVEDDVI ENVKSSLSSYEYCQPPKSVEKICIIDNMYMGKCGDKFFPIVMNDKNICLL DHAWRFPCAGRKVNFNEKPVVMEIPSLMTVKVMFDLDSTFDDILGKVCSE FEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQVRAFLNKLNENVVY LFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDDEDV VTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDV VTGDNDDEDVVTGDNDDEDVVTGDNNDEDVVTGDNNDEESVTGDNDDQIV VTGDDVDDIESIYDFDTYKALLVFNDVYNDALFVSYGSSVETETYFKVNG LWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDY LLTTIPKAIVLPQGGYVADFAYWFLNQFDINAYANWCCLKCGFSFDLNGL DAVFFYGDIVSHVCKCGHNMTLIAADLPCTLHFSLFDDNFCAFCTPKKIF IAACAVDVNVCHSVAVIGDEQIDGKFVTKFSGDKFDFIVGYGMSFSMSSF ELAQLYGLCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKA IAVAAGKKFSKETAAMVKSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQ DGRQSYVLLARAYKHLNNYDCCLSTLISAGIFSVPADVSLTYLLGVVDKQ VILVSNNKEDFDIIQKCQITSVVGTKALAVRLTANVGRVIKFETDAYKLF LSGDDCFVSNSSVIQEVLLLRHDIQLNNDVRDYLLSKMTSLPKDWRLINK FDVINGVKTVKYFECPNSIYICSQGKDFGYVCDGSFYKATVNQVCVLLAK KIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADK ILYQYENLSLADISAVQSSFGFDQQQLLAYYNFLTVCKWSVVVNGPFFSF EQSHNNCYVNVACLMLQHINLKFNKWQWQEAWYEFRAGRPHRLVALVLAK GHFKFDEPSDATDFIRVVLKQADLSGAICELELICDCGIKQESRVGVDAV MHFGTLAKTDLFNGYKIGCNCAGRIVHCTKLNVPFLICSNTPLSKDLPDD VVAANMFMGVGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLTDCLYLKN LTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYTKPIIKAQFKPFA KVDGVYTNFKLVGHDICAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLA SDDLYVKRYFKGCETFGKPVIWFCHDEASLNSLTYFNKPSFKSENRYSVL SVDSVSEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSS IKVVKSLSLVDVWDMYLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI TIPIDLLCLRDDNQTLLVPKIFKARAIEFYGFLKWLFIYVFSLLHFTNDK TIFYTTEIASKFTFNLFCLALKNAFQTFRWSIFIKGFLVVATVFLFWFNF LYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTICDFYSKLGVGFT SHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFDYVSLVKLIVE LVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCS TIVGGVIRYYDITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELS KELKRPVNPTDASHYVVTDIKQVGCMMRLFYDRDGQRVYDDVDASLFVDI NNLLHSKVKVVPNLYVVVVESDADRANFLNAVVFYAQSLYRPILLVDKKL ITTACNGISVTQIMFDVYVDTFMSHFDVDRKSFNNFVNIAHASLREGVQL EKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNLVP TYLKSDNIVAADLGVLIQNGAKHVQGNVAKVANISCIWFIDAFNQLTADL QHKLKKACVKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFF ISLICFILLWALLPTYSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFA NKFFQFDQWYESTFGSVYYHNSMDCPIVVAVMDEDIGSTMFNVPTKVLRY GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYASGCVLSSLCTMFKRGDG TPHPYCYTDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISEGIVRIV RTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDFFDL FYQFFSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTS VVVINVIVWCINFLMLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHL QWIVMYGAIMPFWFCVTYVAMVIANHVLWLFSYCRKIGVNVCSDSTFEET SLTTFMITKDSYCRLKNSVSDVAYNRYLSLYNKYRYYSGKMDTAAYREAA CSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKMVSPTSKIEPC LVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDF TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLA AYNGRPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLE LSTGCHTGTDFNGNFYGPYRDAQVVQLPVKDYVQTVNVIAWLYAAILNNC AWFVQNDVCSIEDFNVWAMTNGFSQVKADLVLDALASMTGVSIETLLAAI KRLYMGFQGRQILGSCTFEDELAPSDVYQQLAGVKLQSKTKRFIKETIYW ILISTFLFSCIISAFVKWTIFMYINTHMIGVTLCVLCFVSFMMLLVKHKH FYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSHFVPAVNFTYVYEV FYGCILCVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVL LFITAFLGTYTWTTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLF IGYILSCYWGFFSLLNSVFRMPMGVYNYKISVQELRYMNANGLRPPRNSF EAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCANVVLLNCLQHLHVASNS KLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFSNPAAVDTKCLASIDE VSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIK QLEKACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSA LQTMLFSMVRKLDNQALNSILDNAVKGCVPLSAIPALAANTLTIIIPDKQ VFDKVVDNVYVTYAGSVWHIQTVQDADGINKQLTDISVDSNWPLVIIANR YNEVANAVMQNNELMPHKLKIQVVNSGSDINCNIPTQCYYNNVSSGRIVY AVLSDVDGLKYTKIMKDDGNCVVLELDPPCKFSIQDVKGLKIKYLYFIKG CNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKTYLDY IQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRAR VEHPDVDGICKLRGKFVQVPLGIKDPILYVLTHDVCQVCGFWRDGSCSCV GSSVAVQSKDLNFLNGLGVLV
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
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Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix