| Visitors: | 312927 |
|---|---|
| # of TMPs: | 15327 |
| Server version: | v2.0.0 |
| Database release: | d.2.2 |
| Release date: | 22.07.2024 |
HTP viewer for RYR_DROME
RYR_DROME
Ryanodine receptor
Evidence:
Exists
Reliability:
60.57
# of TM segments:
9
Cross ref(s)::
UniProt: RYR_DROME
MAEAEGGSEQDDVSFLRTEDMVTLSCTATGERVCLAAEGFGNRHCFLENI ADKNVPPDLSQCVFVIEQALSVRALQELVTAAGSETGKGTGSGHRTLLYG NAILLRHHNSDMYLACLSTSSSNDKLSFDVGLQEHSQGEACWWTVHPASK QRSEGEKVRVGDDLILVSVATERYLHTTKENEQSIVNASFHVTHWSVQPY GTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTWGREAGQNIVIYEGGV VMAQARSLWRLELARTKWTGGFINWYHPMRIRHITTGRYLGVNDSNELIL VKKEEASIATTTFCLRQEKDDEKKVLEDKDLEVIGSPIIKYGDTTVIVQH CETSLWLSYKSYETKKKGVGKVEEKQAILHEEGKMDDCLDFSRSQEEESK TARVIRKCSSLFTQFITALETLQSNRRHSIFFQKVNLNEMVMCLEDLINY FSQPEDDMEHEEKQNRFRALRNRQDLFQEEGVLNLILEAIDKINIITSQG FLASFLAGDETGQSWDLISTYLYQLLAAIIKGNHTNCAQFANSNRLNWLF SRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEKHGRD PKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTLLVDHVASIRP NIFVGRVDGSSMYQKWYFEVTMDHIEQTTHMMPHLRIGWANTSGYVPYPG GGKKWGGNGVGDDLYSFGFDGAFLWTGGRKTLVVDALPEEPFIRKGDVIG VAIDLSVPIITFTFNGVKVRGSFRDFNLDGMFFPVMSCSSKLSCRFLFGG DHGRLKFAPPMGFSALVQCLMPQQILSLDPCFYFGNLAKNVLAGPWLIED DTAFVPKPVDTTGVTLPSSVDQIKEKLAENIHEMWALNKIEAGWSWGEHR DDYHRIHPCLTHFEKLPAAEKRYDNQLAVQTLKTIISLGYYITMDKPPAR IRPVRLPNEIFMQGNGYKPAPLDLSAVTLTPKLEELVDQLAENTHNLWAR ERIQQGWTYGLNEDSENHRSPHLVPYAKVDEAIKKANRDTASETVRTLLV YGYVLDPPTGEGTEALLAEAQRLKFAGFRTYRVERNYAVTSGKWYFEFEV LTSGPMRVGWARADCYPGAMLGSEDTSWAFDGHNVTKMHAGSIEHFGVRY EAGDVIGCFIDVKEQTISFSLNGELLMDALGGETTFADVTAEGVGFVPAC TLGVGQKARLIYGQDVDSLKFFTTCGLQEGYEPFCVNMRRPVTHWYTKDQ PIFENTEEMPDCRIDVTRIPGGADTPPHLKISHNTFETMEKANWEFLRLS LPVTCMGEFISEQEKARRWDEIKNRQYRLMREAEIAAQMQVQTQAAHMDH MLKGGFNMNDIKGLTRNFDEHADAEADHMMRGPNRPPRKGSLTRNITFET DMSAALDEMQRSTSVLDMNGLGEEMDDKKKRGRSPFKFFSKKSRDQSREK MGARTLDTSLERRNTVAHGRNVVNQQMTTRAPTLRLNNAEIPPSPVPQGP KQLSGSNLGQQPVETSGDEMFDAECLKLINEYFYGVRIFPGQDPTHVYVG WVTTQYHLHSREFNKNKVRRGSVYIEDDYEMAIERIDRQSCYVVRADELF NEVTQDASGKGASQGMFVGCFVDTATGIIRFTCEGKDTSHRWMMEPDTKL FPAIFVEATSKEILQIELGRTPTTLPLSAAVLPTSDKHINPQSPPRLKVQ CLRPHQWARVPNTALQVHALKLSDVRGWSMLCEDPVSMLALHIPEEDRCI DILELIEMDKLLSFHAHSLTLYAALCYQSNYRAAHALCQHVDQKQLLYAI RSEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEYITPLGAELKELYSD EEMQHSLRSLVTESVRPQLRMTEITPPVIATSSMPSVSSEPIPDIDQLYS PKFPLEVVRQFVMEALKDAVEINQVHNRDPIGWTNENLFLPLIKLTDRLL LVGVLTDEDVQRLLVMIDPETWDQAFEREGKDEHRKGLLTMKMAEGAKLQ MCYLLHHLYDTQLRHRVESIIAFSHDFVGDLQTDQLRRYIEIKQSDLPSA VAAKKTKEFRCPPREQMNQILCFKNLEPDDQDNCTCGLELRGRLGDFHDS LMQKVSLNALQEPDGVEGTAIEEVKTGPITKIYNFINTVKELEEGPKEVE EPEKKTPEEVFRKVLIKTIVSWAEESQIENPKLVREMFSLLLRQYDTVGE LVRALEKTYVINTRARDDVAEMWVGLSQIRALLPVQMSQEEEELMRKRLW KLVNNATFFQHPDLIRILRVHENVMAVMMNTLGRRAQAQSDAPTQSEVAE GAPSKEKDTSHEMVVACCRFLCYFCRTGRQNQKAMFDHFDFLLDNANILL ARPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQSNSE LVEKGYPDLGWDPVEGERYLDFLRYCVWVNGESVEENANLVIRLLIRRPE CLGPALRGEGEGLFRAIVEANRMSERISDRCKMQDEAEGTIAGLNFTHPL PEGEEDEDYIDTGAAILNFYCTLVDLLGRCAPDASVIEQGKNESLRARAI LRSLVPLEDLQGVLSLKFTLSQTAPGEEKPKSDMPSGLLPNNKQSIVLFL ERVYGIEAQDLFYRLLEDAFLPDLRTATILDKSDGSESDMALAMNRYIGN SILPLLIKHSKFYNEAENYASLLDATLHTVYRLSKNRMLTKGQREAVSDF LVALTSQMQPAMLLKLLRKLTVDVSKLSEYTTVALRLLTLHFDRCAKYYG STQGQGSYGASSDEEKRLTMLLFSNIFDSLSNMDYDPELFGKALPCLIAI GCALPPDYSLSKNTDEDYYGRQMGAPDQPQYMPNPIDTNNVHLDNDLNSL VQKFSEHYHDAWASRRLEGGWTYGDIRSDNDRKHPRLKPYNMLSEYERER YRDPVRECLKGLLAIGWTVEHSEVEVALNHRGSTRRQSKPQINEFQNEGS PFNYNPHPVDMSNLTLSREMQNMAERLAENSHDIWAKKKNEELNGCGGVI HPQLVPYDLLTDKEKKKDRERSQEFLKYMQYQGYKLHKPSKGGAVEEGGA TQAAVELRFSYSLLEKLIQYLDRATINMKLLKPSTTFSRRSSFKTATRDI KFFSKVVLPLMEKYFSTHRNYFIAIATATNNIGAASLKEKEMVASIFCKL AALLRNRLSAFGPDVRITVRCLQVLVKGIDARTLTKNCPEFIRTSMLTFF NQTSDDLGNTILNLQDGKYSHLRGTHLKTSTSLGYVNQVVLPVLTAMFDH LAACDYGSDLLLDEIQVASYKILAALYHLGTDGTLTHDRKYLKTEIERHR PALGSCLGAYSSCFPVAFLEPHLNKHNQYSLLNRIADHSLEAQDIMVKME SCMPNLETILAEVDQFVESDKTYNDAPHIIDVILPLLCAYLPFWWSQGPD NVSPTSGNHVTMVTADHMNPLLRNVLKMIKKNIGNDNAPWMTRIAAYTQQ IIINTSEELLKDPFLPLAERVKKRTENMLHKEDSMRGFIKSATDDTSQVE TQLQEDWNLLVRDIYSFYPLLIKYVDLQRNHWLKDNIPEAEELYNHVAEI FNIWSKSQYFLKEEQNFISANEIDNMALIMPTATRRSAISEGAPAVGGKV KKKKKNRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKD RYLKKMPEYDVIEFARNQLTLPDKLDPSDEMSWQHYLYSKLGKTEEPVDE QALEKANVNSNEKGKDKTQETVDRIVAMAKVLFGLHMIDHPQQQSKNVYR SVVSIQRKRAVIACFRQTSLHSLPRHRACNIFARSYYEQWLQEENVGQEV MVEDLTQTFEDSEKSKKEGEETDSKPDPLTQLVTTFCRGAMTERSGALQE DLLYMSYAQIAAKSTGKEEEEGGDEEGGEGGEEGEGTSIHEQEMEKQKLL FHQARLSNRGVAEMVLLHISASKGIPSEMVMTTLNLGIAILRGGNIDIQM GMLNHLKEKKDVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGSEGAA GEKNMHDAEFTCALFRFIQLTCEGHNLEWQNYLRTQAGNTTTVNVVICTV DYLLRLQESIMDFYWHYSSKEIIDPAGKANFFKAIEVASQVFNTLTEVIQ GPCTLNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQVDLLKELLNLQ KDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLAD LIESPSFHEVDMKNEGWVTPKDFREKMEQSKNYTPEEMDFLLACCERNHE GKIDYRAFVEHFHEPSKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSV LNYFEPFLGRIEILGSSKRIERVYFEIKDSNIEQWEKPQIRESKRAFFYS IVTEGGDKEKLEAFVNFCEDAIFEMTHASGLMATDDGGGNVKRDTAYSSY MSEEEEERAARDPIRRTITAVKEGLKFGVHMLSPANIKHQIGVMQTKSIP ELIVGFFKIIFYIFYYTGYAHFCVVRYIFGILLNLMRGPAPEQEEEPVVE EETFGRALPPLPLEEPPGTVQAFGLDINKEENGMYKVVVHESPANSSMEE GGESSPEDGAAASGELVEGEPHQEPISIVDLLGGEAAKKAAQERQEAQKA QEAAMASIEAEAKKSSSAPQETPAVHQIDFSQYTHRAVSFLARNFYNLKY VALVLAFSINFMLLFYKVTSFTEEADSSAEEELILGSGSGGGADITGSGF GGSGDGGSGDGEMEDEIPELVHVDEDFFYMEHVLRIAACLHSLVSLAMLI AYYHLKVPLAIFKREKEIARRLEFEGLFIAEQPEDDDFKSHWDKLVISAK SFPVNYWDKFVKKKVRQKYSETYDFDSISNLLGMEKSTFAAQESEETGIF KYIMNIDWRYQVWKAGVTFTDNAFLYSLWYFSFSVMGNFNNFFFAAHLLD VAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQ EEDEEVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGDPDGDDYEVYRIIF DITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKDNMESNCFICGMGKD FFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQ RSWDFFPVGDCFRKQYEDELSGGGGGG
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix