THAQ_BURTA
Polyketide synthase ThaQ
MRRAMRDGGKPDRIGAAAPLRRAPLTATSGIDMNVQESIFPITPNGFAGH
SMDDLMQRWLLAQLQATGILADGRAHAFDALAGRVQPLYRRWLEESLRLL
RDAGLVRDDAQGWRAAERAPIDARDAQRHWDASRDAWLADRERAVYVVLI
EAVLAQLPAILTGRRRATDVLFPNGSMARVQGVYTGNHVSDHFNRVLVDH
AVRYVAGCAARRADAKLRFIEVGAGTGGTTEGLLAALAPHARHVGEYCFT
DISKAFLNHAQRRFGEGAPFFGARVLDIEQPIDAQGFEPGAYDALVATNV
LHATRDIRTTLRHCKALLKHNGLLFINEMTGSVPYLHLTFGMLEGWWRFT
DDALRVAGCPAVAPQTWDRVLREEGFSSVIFPARDAHGQGQQIVIAQNDA
RRAGSARRDARASNGDAQHGARHEAAHDAQQDASGDTQADAHDSAHDSAH
DSAHDSAHDSAHDSAHAAAALRREGRAYLRARAAELLGMPAGAIDPDEGL
HAYGLDSILASQFAAQLAEAFDGFDGALLFEHKTINALLDHLLAAHADAL
ARLLPPAGGAPARGVGARAQAAQASGEGRAAPPAAPHADARSDTPSSAPS
SAPARPDQPAPSGPPAQPAQPAPRADTPPPAASAGHRGEARASDTRYAPR
APHPDAAAEPVAIIGISGRYPGAYDVPAFWRNLLAGACAITEVPAERWDW
RAHYRADAAEAAREGKSYSKWGGFVDDVGRFDPAFFGMTPQDAQHTDPQE
LLFLEMCWHALQDAGQTPALLPGDVRRRAGVFAAITKHYAFPPTSFASLA
NRVSHALDFGGKSLAIDTMCSSSLVAVNEAWEYLQRDGRLAVVGGVNLYL
DPQQYAHLSRFRFASSGPVCKAFGEGGDGFVPGEGAGAIVLKRLSDAERD
GDPIHAVIRGCAVNHNGRSTSFTASDPARQADVVRDALTRAGVDPRTIGY
VEAAANGHAMGDAIEMTGLGKVFAACDGVSGTRAIGSVKANIGHCEAASG
MSQLTKVVMAMRDGVLAPTLRDGTRNPNIAFERLPFEVQEQAAPWRRLIV
DGSEVPRRAGVTSIGGGGVNAHVVLEEYVAPPRAARPGAGTDDEVLFVLS
ARTREQLGAYAERWAGYLEAHPDCDVDAIAHTVRTAREPMAHRLAVLAHG
RGELAALLRGWAAGGAASGAASGAASDQVFYGDVKQHRVVLSDALVQAAR
REGAASLAKLWVLGNALGAAHGADEPAPRRVGLLPPYPFERRLVWTSAHA
PGTRHASAGEATEAAEAAEAAEAGAAAVAESAEAGAPAAAGDARLQPAPA
SNAEAFYSLSTLNASKDFQEQYLTLCPFPERIPGFSMTRMFIEPQKYPNE
FALMQARQIEMRQVLFGREHFERISRVLDIGCGMGTDVIQLAKRFAHLRT
TGYTITRAQAELGAGRIAREGLQGRAEIRHGDSAKDPFPGKYDLVIGIEV
ICHIQDKHGVFGNIARSLDDDGHVLLMDFVANGRGRISSPEIDIDIGTRQ
DWIDVAAAHGLVVDEVIDVSPQIANFLHDPEHERNIAALPGVAQASFRNF
ANTCVSLEKGWVSYCLLRLSKASRLSEAERRRLNAERFGASVAYPDALKA
MHARGPAPYPRSPDAQPPAARAQAGVDGGVEASAPAGVKADSKAGPKSEV
KSDAAARASRADIAASVAASVAASVEDAFEASLGLRRADLERADDLRALG
IGSIQAVMLAEAINERLDLALPSRFVLEHATFGALVRAVAEAVAGGRGSS
RDAPARELAYLSLLEPGGAMTAELLELPGGARAEILRGGRGPRVVLIPGL
GMAGTVFRDLCRALTRRHEVIVYHYPGLGRSDPVAPIDVDAAAAHLYRTL
DACGGDGAAALLGWSFGGVIAQRAALMRPRAWRALVLVNTLGAYRPLAPQ
FLTPGASRDGEPRGLGGLYQTDLDFVFAGDAPPAALARKDACAALMRDSL
ALDAAQAIDYLDALVRFDATAQLPSLRMPTLVVAGTADHFGDPAHAEQLV
SLIPNARLARIAGAGHAVFLTHGEAFEPAVLAFLDETLRAAEAGGAAESV
ESVEATEAAEAARSPAVARRRATDDAPVGSDA
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
