TTC3_HUMAN
E3 ubiquitin-protein ligase TTC3
MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGV
QYKDYIQSERNLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNS
SVISRLHPCVDANNSRASEINLKKLQHLELMEDIVDLAKKVANDSFLIGG
LLRIGCKIENKILAMEEALNWIKYAGDVTILTKLGSIDNCWPMLSIFFTE
YKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNEEFSKERFDIA
IIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK
GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQI
EDLQGRTANKDPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINH
EMANGGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESE
KFSSSSPLTLPADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMA
LLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAISLLGIG
QPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE
KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAI
CCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTF
NDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPR
PILKQKCSSLEKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKN
EEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAMLLKELLSWKV
LSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE
PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLD
SIEGKQLDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSR
CTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTSNNEII
TSSEDHSNRNSDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWD
MNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPEETRQILEKAG
GLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEY
VRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACE
DVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVL
EDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLPQYTSIYT
PLASLSPEYQLPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQI
ASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGNSNNKCEVIPE
STSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQ
VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQ
DLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHEL
HLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKE
SEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKE
IEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSG
DDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPE
ATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEH
LSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKK
KKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRI
ALGASSCEICHEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRD
LLTEESPSGRGWPSQNQELPSCSSR
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
