UBR1_HUMAN
E3 ubiquitin-protein ligase UBR1
MADEEAGGTERMEISAELPQTPQRLASWWDQQVDFYTAFLHHLAQLVPEI
YFAEMDPDLEKQEESVQMSIFTPLEWYLFGEDPDICLEKLKHSGAFQLCG
RVFKSGETTYSCRDCAIDPTCVLCMDCFQDSVHKNHRYKMHTSTGGGFCD
CGDTEAWKTGPFCVNHEPGRAGTIKENSRCPLNEEVIVQARKIFPSVIKY
VVEMTIWEEEKELPPELQIREKNERYYCVLFNDEHHSYDHVIYSLQRALD
CELAEAQLHTTAIDKEGRRAVKAGAYAACQEAKEDIKSHSENVSQHPLHV
EVLHSEIMAHQKFALRLGSWMNKIMSYSSDFRQIFCQACLREEPDSENPC
LISRLMLWDAKLYKGARKILHELIFSSFFMEMEYKKLFAMEFVKYYKQLQ
KEYISDDHDRSISITALSVQMFTVPTLARHLIEEQNVISVITETLLEVLP
EYLDRNNKFNFQGYSQDKLGRVYAVICDLKYILISKPTIWTERLRMQFLE
GFRSFLKILTCMQGMEEIRRQVGQHIEVDPDWEAAIAIQMQLKNILLMFQ
EWCACDEELLLVAYKECHKAVMRCSTSFISSSKTVVQSCGHSLETKSYRV
SEDLVSIHLPLSRTLAGLHVRLSRLGAVSRLHEFVSFEDFQVEVLVEYPL
RCLVLVAQVVAEMWRRNGLSLISQVFYYQDVKCREEMYDKDIIMLQIGAS
LMDPNKFLLLVLQRYELAEAFNKTISTKDQDLIKQYNTLIEEMLQVLIYI
VGERYVPGVGNVTKEEVTMREIIHLLCIEPMPHSAIAKNLPENENNETGL
ENVINKVATFKKPGVSGHGVYELKDESLKDFNMYFYHYSKTQHSKAEHMQ
KKRRKQENKDEALPPPPPPEFCPAFSKVINLLNCDIMMYILRTVFERAID
TDSNLWTEGMLQMAFHILALGLLEEKQQLQKAPEEEVTFDFYHKASRLGS
SAMNIQMLLEKLKGIPQLEGQKDMITWILQMFDTVKRLREKSCLIVATTS
GSESIKNDEITHDKEKAERKRKAEAARLHRQKIMAQMSALQKNFIETHKL
MYDNTSEMPGKEDSIMEEESTPAVSDYSRIALGPKRGPSVTEKEVLTCIL
CQEEQEVKIENNAMVLSACVQKSTALTQHRGKPIELSGEALDPLFMDPDL
AYGTYTGSCGHVMHAVCWQKYFEAVQLSSQQRIHVDLFDLESGEYLCPLC
KSLCNTVIPIIPLQPQKINSENADALAQLLTLARWIQTVLARISGYNIRH
AKGENPIPIFFNQGMGDSTLEFHSILSFGVESSIKYSNSIKEMVILFATT
IYRIGLKVPPDERDPRVPMLTWSTCAFTIQAIENLLGDEGKPLFGALQNR
QHNGLKALMQFAVAQRITCPQVLIQKHLVRLLSVVLPNIKSEDTPCLLSI
DLFHVLVGAVLAFPSLYWDDPVDLQPSSVSSSYNHLYLFHLITMAHMLQI
LLTVDTGLPLAQVQEDSEEAHSASSFFAEISQYTSGSIGCDIPGWYLWVS
LKNGITPYLRCAALFFHYLLGVTPPEELHTNSAEGEYSALCSYLSLPTNL
FLLFQEYWDTVRPLLQRWCADPALLNCLKQKNTVVRYPRKRNSLIELPDD
YSCLLNQASHFRCPRSADDERKHPVLCLFCGAILCSQNICCQEIVNGEEV
GACIFHALHCGAGVCIFLKIRECRVVLVEGKARGCAYPAPYLDEYGETDP
GLKRGNPLHLSRERYRKLHLVWQQHCIIEEIARSQETNQMLFGFNWQLL
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
