| Visitors: | 312927 |
|---|---|
| # of TMPs: | 15327 |
| Server version: | v2.0.0 |
| Database release: | d.2.2 |
| Release date: | 22.07.2024 |
HTP viewer for A0A994J483_HUMAN
A0A994J483_HUMAN
HECT-type E3 ubiquitin transferase
Evidence:
Exists
Reliability:
61.75
# of TM segments:
10
Cross ref(s)::
UniProt: A0A994J483_HUMAN
MKVDRTKLKKTPTEAPADCRALIDKLKVCNDEQLLLELQQIKTWNIGKCE LYHWVDLLDRFDGILADAGQTVENMSWMLVCDRPEREQLKMLLLAVLNFT ALLIEYSFSRHLYSSIEHLTTLLASSDMQVVLAVLNLLYVFSKRSNYITR LGSDKRTPLLTRLQHLAESWGGKENGFGLAECCRDLHMMKYPPSATTLHF EFYADPGAEVKIEKRTTSNTLHYIHIEQLDKISESPSEIMESLTKMYSIP KDKQMLLFTHIRLAHGFSNHRKRLQAVQARLHAISILVYSNALQESANSI LYNGLIEELVDVLQITDKQLMEIKAASLRTLTSIVHLERTPKLSSIIDCT GTASYHGFLPVLVRNCIQAMIDPSMDPYPHQFATALFSFLYHLASYDAGG EALVSCGMMEALLKVIKFLGDEQDQITFVTRAVRVVDLITNLDMAAFQSH SGLSIFIYRLEHEVDLCRKECPFVIKPKIQRPNTTQEGEEMETDMDGVQC IPQRAALLKSMLNFLKKAIQDPAFSDGIRHVMDGSLPTSLKHIISNAEYY GPSLFLLATEVVTVFVFQEPSLLSSLQDNGLTDVMLHALLIKDVPATREV LGSLPNVFSALCLNARGLQSFVQCQPFERLFKVLLSPDYLPAMRRRRSSD PLGDTASNLGSAVDELMRHQPTLKTDATTAIIKLLEEICNLGRDPKYICQ KPSIQKADGTATAPPPRSNHAAEEASSEDEEEEEVQAMQSFNSTQQNETE PNQQVVGTEERIPIPLMDYILNVMKFVESILSNNTTDDHCQEFVNQKGLL PLVTILGLPNLPIDFPTSAACQAVAGVCKSILTLSHEPKVLQEGLLQLDS ILSSLEPLHRPIESPGGSVLLRELACAGNVADATLSAQATPLLHALTAAH AYIMMFVHTCRVGQSEIRSISVNQWGSQLGLSVLSKLSQLYCSLVWESTV LLSLCTPNSLPSGCEFGQADMQKLVPKDEKAGTTQGGKRSDGEQDGAAGS MDASTQGLLEGIGLDGDTLAPMETDEPTASDSKGKSKITPAMAARIKQIK PLLSASSRLGRALAELFGLLVKLCVGSPVRQRRSHHAASTTTAPTPAARS TASALTKLLTKGLSWQPPPYTPTPRFRLTFFICSVGFTSPMLFDERKYPY HLMLQKFLCSGGHNALFETFNWALSMGGKVPVSEGLEHSDLPDGTGEFLD AWLMLVEKMVNPTTVLESPHSLPAKLPGGVQNFPQFSALRFLVVTQKAAF TCIKNLWNRKPLKVYGGRMAESMLAILCHILRGEPVIRERLSKEKEGSRG EEDTGQEEGGSRREPQVNQQQLQQLMDMGFTREHAMEALLNTSTMEQATE YLLTHPPPIMGGVVRDLSMSEEDQMMRAIAMSLGQDIPMDQRAESPEEVA CRKEEEERKAREKQEEEEAKCLEKFQDADPLEQDELHTFTDTMLPGCFHL LDELPDTVYRVCDLIMTAIKRNGADYRDMILKQVVNQVWEAADVLIKAAL PLTTSDTKTVSEWISQMATLPQASNLATRILLLTLLFEELKLPCAWVVES SGILNVLIKLLEVVQPCLQAAKEQKEVQTPKWITPVLLLIDFYEKTAISS KRRAQMTKYLQSNSNNWRWFDDRSGRWCSYSASNNSTIDSAWKSGETSVR FTAGRRRYTVQFTTMVQVNEETGNRRPVMLTLLRVPRLNKNSKNSNGQEL EKTLEESKEMDIKRKENKGNDTPLALESTNTEKETSLEETKIGEILIQGL TEDMVTVLIRACVSMLGVPVDPDTLHATLRLCLRLTRDHKYAMMFAELKS TRMILNLTQSSGFNGFTPLVTLLLRHIIEDPCTLRHTMEKVVRSAATSGA GSTTSGVVSGSLGSREINYILRVLGPAACRNPDIFTEVANCCIRIALPAP RGSGTASDDEFENLRIKGPNAVQLVKTTPLKPSPLPVIPDTIKEVIYDML NALAAYHAPEEDKSDPKPGVMTQEVGQLLQDMGDDVYQQYRSLTRQSSDF DTQSGFSINSQVFAADGASTETSASGTSQGEASTPEESRDGKKDKEGDRA SEEGKQKGKGSKPLMPTSTILRLLAELVRSYVGIATLIANYSYTVGQSEL IKEDCSVLAFVLDHLLPHTQNAEDKDTPALARLFLASLAAAGSGTDAQVA LVNEVKAALGRALAMAESTEKHARLQAVMCIISTIMESCPSTSSFYSSAT AKTQHNGMNNIIRLFLKKGLVNDLARVPHSLDLSSPNMANTVNAALKPLE TLSRIVNQPSSLFGSKSASSKNKSEQDAQGASQDSSSNQQDPGEPGEAEV QEEDHDVTQTEVADGDIMDGEAETDSVVIAGQPEVLSSQEMQVENELEDL IDELLERDGGSGNSTIIVSRSGEDESQEDVLMDEAPSNLSQASTLQANRE DSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEG EEGDEDDDDDGSEMELDEDYPDMNASPLVRFERFDREDDLIIEFDNMFSS ATDIPPSPGNIPTTHPLMVRHADHSSLTLGSGSSTTRLTQGIGRSQRTLR QLTANTGHTIHVHYPGNRQPNPPLILQRLLGPSAAADILQLSSSLPLQSR GRARLLVGNDDVHIIARSDDELLDDFFHDQSTATSQAGTLSSIPTALTRW TEECKVLDAESMHDCVSVVKVSIVNHLEFLRDEELEERREKRRKQLAEEE TKITDKGKEDKENRDQSAQCTASKSNDSTEQNLSDGTPMPDSYPTTPSST DAATSESKETLGTLQSSQQQPTLPTPPALGEVPQELQSPAGEGGSSTQLL MPVEPEELGPTRPSGEAETTQMELSPAPTITSLSPERAEDSDALTAVSSQ LEGSPMDTSSLASCTLEEAVGDTSAAGSSEQPRAGSSTPGDAPPAVAEVQ GRSDGSGESAQPPEDSSPPASSESSSTRDSAVAISGADSRGILEEPLPST SSEEEDPLAGISLPEGVDPSFLAALPDDIRREVLQNQLGIRPPTRTAPST NSSAPAVVGNPGVTEVSPEFLAALPPAIQEEVLAQQRAEQQRRELAQNAS SDTPMDPVTFIQTLPSDLRRSVLEDMEDSVLAVMPPDIAAEAQALRREQE ARQRQLMHERLFGHSSTSALSAILRSPAFTSRLSGNRGVQYTRLAVQRGG TFQMGGSSSHNRPSGSNVDTLLRLRGRLLLDHEALSCLLVLLFVDEPKLN TSRLHRVLRNLCYHAQTRHWVIRSLLSILQRSSESELCIETPKLTTSEEK GKKSSKSCGSSSHENRPLDLLHKMESKSSNQLSWLSVSMDAALGCRTNIF QIQRSGGRKHTEKHASGGSTVHIHPQAAPVVCRHVLDTLIQLAKVFPSHF TQQRTKETNCESDRERGNKACSPCSSQSSSSGICTDFWDLLVKLDNMNVS RKGKNSVKSVPVSAGGEGETSPYSLEASPLGQLMNMLSHPVIRRSSLLTE KLLRLLSLISIALPENKVSEAQANSGSGASSTTTATSTTSTTTTTAASTT PTPPTAPTPVTSAPALVAATAISTIVVAASTTVTTPTTATTTVSISPTTK GSKSPAKVSDGGSSSTDFKMVSSGLTENQLQLSVEVLTSHSCSEEGLEDA ANVLLQLSRGDSGTRDTVLKLLLNGARHLGYTLCKQIGTLLAELREYNLE QQRRAQCETLSPDGLPEEQPQTTKLKGKMQSRFDMAENVVIVASQKRPLG GRELQLPSMSMLTSKTSTQKFFLRVLQVIIQLRDDTRRANKKAKQTGRLG SSGLGSASSIQAAVRQLEAEADAIIQMSESSQSEASVRREESPMDVDQPS PSAQDTQSIASDGTPQGEKEKEERPPELPLLSEQLSLDELWDMLGECLKE LEESHDQHAVLVLQPAVEAFFLVHATERESKPPVRDTQTHRTVLNQILRQ STTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVR RDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISRE MFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDL TFSTEVQEFGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQ LAAFLEGFYEIIPKRLISIFTEQELELLISGLPTIDIDDLKSNTEYHKYQ SNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQK FQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFG LA
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix
Legend:
Inside
Membrane
Outside
Re-entrant loop
Beta barrel inside
Periplasm
Interfacial helix